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Mitochondrial dysfunction and tissue injury by alcohol, high fat, nonalcoholic substances and pathological conditions through post-translational protein modificationsFunctional roles of protein nitration in acute and chronic liver diseasesSystematic study of mitochondrial toxicity of environmental chemicals using quantitative high throughput screening.High-throughput respirometric assay identifies predictive toxicophore of mitochondrial injury.Mitochondrial pharmacology: electron transport chain bypass as strategies to treat mitochondrial dysfunction.Mn bioavailability by polarized Caco-2 cells: comparison between Mn gluconate and Mn oxyprolinate.Xenobiotics that affect oxidative phosphorylation alter differentiation of human adipose-derived stem cells at concentrations that are found in human blood.OXPHOS mutations and neurodegenerationRole of CYP2E1 in mitochondrial dysfunction and hepatic tissue injury in alcoholic and non-alcoholic diseases.Increased nitroxidative stress promotes mitochondrial dysfunction in alcoholic and nonalcoholic fatty liver disease.Predictive toxicology approaches for small molecule oncology drugs.Cardiotoxicity associated with targeting kinase pathways in cancer.Quantitative glucose and ATP sensing in mammalian cells.Mitochondria as a pharmacological target: magnum overview.The Promise of New Technologies to Reduce, Refine, or Replace Animal Use while Reducing Risks of Drug Induced Liver Injury in Pharmaceutical Development.Cardiomyocytes are Protected from Antiretroviral Nucleoside Analog-Induced Mitochondrial Toxicity by Overexpression of PGC-1α.Cisplatin Toxicity in Dorsal Root Ganglion Neurons Is Relieved by Meclizine via Diminution of Mitochondrial Compromise and Improved Clearance of DNA Damage.Fluorescence-Based Microplate Assays for In Vitro Assessment of Mitochondrial Toxicity, Metabolic Perturbation, and Cellular Oxygenation.High-content screening for compounds that affect mtDNA-encoded protein levels in eukaryotic cells.Janice Drew's work on diet and cancer.Cisplatin as an anti-tumor drug: cellular mechanisms of activity, drug resistance and induced side effectsThe antiestrogen 4-hydroxytamoxifen protects against isotretinoin-induced permeability transition and bioenergetic dysfunction of liver mitochondria: comparison with tamoxifen.Mitochondrial and liver oxidative stress alterations induced by N-butyl-N-(4-hydroxybutyl)nitrosamine: relevance for hepatotoxicity.Clinical effects of chemical exposures on mitochondrial function.Unraveling Environmental Effects on Mitochondria.Mitochondrial pharmacology: its future is now.Dissociation of the vacuolar and macroautophagic cytopathology from the cytotoxicity induced by the lipophilic local anesthetic bupivacaine.Effects of mid-respiratory chain inhibition on mitochondrial function in vitro and in vivo.
P2860
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P2860
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 22 May 2008
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Mitochondrial off targets of drug therapy.
@en
Mitochondrial off targets of drug therapy.
@nl
type
label
Mitochondrial off targets of drug therapy.
@en
Mitochondrial off targets of drug therapy.
@nl
prefLabel
Mitochondrial off targets of drug therapy.
@en
Mitochondrial off targets of drug therapy.
@nl
P1476
Mitochondrial off targets of drug therapy.
@en
P2093
Kendall B Wallace
P304
P356
10.1016/J.TIPS.2008.04.001
P577
2008-05-22T00:00:00Z