PDL-1 blockade impedes T cell expansion and protective immunity primed by attenuated Listeria monocytogenes.
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Herpesvirus exploitation of host immune inhibitory pathwaysImmunoregulation in Fungal DiseasesB7-H1 (programmed cell death ligand 1) is required for the development of multifunctional Th1 cells and immunity to primary, but not secondary, Salmonella infectionAnti-PD-1 antibody significantly increases therapeutic efficacy of Listeria monocytogenes (Lm)-LLO immunotherapy.Role of PD-1 in regulating acute infections.Programmed death-1 (PD-1)-deficient mice are extraordinarily sensitive to tuberculosis.Blocking of PDL-1 interaction enhances primary and secondary CD8 T cell response to herpes simplex virus-1 infection.T cell and APC dynamics in situ control the outcome of vaccinationLupus-prone mice fail to raise antigen-specific T cell responses to intracellular infectionPerinatal Listeria monocytogenes susceptibility despite preconceptual priming and maintenance of pathogen-specific CD8(+) T cells during pregnancy.Increased level of myeloid-derived suppressor cells, programmed death receptor ligand 1/programmed death receptor 1, and soluble CD25 in Sokal high risk chronic myeloid leukemiaA potential new pathway for PD-L1 costimulation of the CD8-T cell response to Listeria monocytogenes infectionAlteration of the thymic T cell repertoire by rotavirus infection is associated with delayed type 1 diabetes development in non-obese diabetic mice.Foxp3(+) regulatory T cell expansion required for sustaining pregnancy compromises host defense against prenatal bacterial pathogensFoxp3+ regulatory T cells impede the priming of protective CD8+ T cells.Programmed death ligand 1 is over-expressed by neutrophils in the blood of patients with active tuberculosisB7-h1 expressed by activated CD8 T cells is essential for their survival.The CTLA-4 and PD-1/PD-L1 inhibitory pathways independently regulate host resistance to Plasmodium-induced acute immune pathology.Virus-specific CD8+ T cells upregulate programmed death-1 expression during acute friend retrovirus infection but are highly cytotoxic and control virus replicationInnate IFN-γ is essential for programmed death ligand-1-mediated T cell stimulation following Listeria monocytogenes infection.Costimulatory and Coinhibitory Receptor Pathways in Infectious DiseaseThe diversity of costimulatory and inhibitory receptor pathways and the regulation of antiviral T cell responses.Local blockade of epithelial PDL-1 in the airways enhances T cell function and viral clearance during influenza virus infection.Programmed death 1 regulates development of central memory CD8 T cells after acute viral infection.B7-H1 antibodies lose antitumor activity due to activation of p38 MAPK that leads to apoptosis of tumor-reactive CD8(+) T cellsPD-L1 limits the mucosal CD8+ T cell response to Chlamydia trachomatis.Inhibitory receptors on lymphocytes: insights from infectionsGD2-specific CAR T Cells Undergo Potent Activation and Deletion Following Antigen Encounter but can be Protected From Activation-induced Cell Death by PD-1 Blockade.MDA5 Is Critical to Host Defense during Infection with Murine Coronavirus.The Spectrum of Serious Infections Among Patients Receiving Immune Checkpoint Blockade for the Treatment of Melanoma.Expression of PD-1/LAG-3 and cytokine production by CD4(+) T cells during infection with Plasmodium parasites.Functional Expression of Programmed Death-Ligand 1 (B7-H1) by Immune Cells and Tumor Cells.Anti-PD-1 Antibody Treatment Promotes Clearance of Persistent Cryptococcal Lung Infection in Mice.The diverse functions of the PD1 inhibitory pathway.Characterization of regulatory dendritic cells differentiated from the bone marrow of UV-irradiated mice.PD-L1 serves as a double agent in separating GVL from GVHD.Cytotoxic T-lymphocyte antigen 4 blockade augments the T-cell response primed by attenuated Listeria monocytogenes resulting in more rapid clearance of virulent bacterial challenge
P2860
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P2860
PDL-1 blockade impedes T cell expansion and protective immunity primed by attenuated Listeria monocytogenes.
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
@pt
bilimsel makale
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scientific article published on June 2008
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
PDL-1 blockade impedes T cell ...... nuated Listeria monocytogenes.
@en
PDL-1 blockade impedes T cell ...... nuated Listeria monocytogenes.
@nl
type
label
PDL-1 blockade impedes T cell ...... nuated Listeria monocytogenes.
@en
PDL-1 blockade impedes T cell ...... nuated Listeria monocytogenes.
@nl
prefLabel
PDL-1 blockade impedes T cell ...... nuated Listeria monocytogenes.
@en
PDL-1 blockade impedes T cell ...... nuated Listeria monocytogenes.
@nl
P2093
P2860
P1476
PDL-1 blockade impedes T cell ...... nuated Listeria monocytogenes.
@en
P2093
James M Ertelt
Jared H Rowe
Sing Sing Way
Tanner M Johanns
P2860
P304
P356
10.4049/JIMMUNOL.180.11.7553
P407
P577
2008-06-01T00:00:00Z