Role of endoplasmic reticulum Ca2+ signaling in the pathogenesis of Alzheimer disease
about
Biophysical and functional characterization of hippocalcin mutants responsible for human dystonia.Reduced synaptic STIM2 expression and impaired store-operated calcium entry cause destabilization of mature spines in mutant presenilin mice.Altered Ca2+ homeostasis induces Calpain-Cathepsin axis activation in sporadic Creutzfeldt-Jakob diseaseAberrant calcium signaling by transglutaminase-mediated posttranslational modification of inositol 1,4,5-trisphosphate receptorsAmyloid-beta: a crucial factor in Alzheimer's disease.The Ca(2+) channel inhibitor 2-APB reverses β-amyloid-induced LTP deficit in hippocampus by blocking BAX and caspase-3 hyperactivationStim and Orai proteins in neuronal Ca(2+) signaling and excitabilitySTIM2 protects hippocampal mushroom spines from amyloid synaptotoxicity.Neuronal Store-Operated Calcium Entry and Mushroom Spine Loss in Amyloid Precursor Protein Knock-In Mouse Model of Alzheimer's Disease.Calstabin 2: An important regulator for learning and memory in mice.Dysregulation of Nutrient Sensing and CLEARance in Presenilin Deficiency.Store-Operated Calcium Channel Complex in Postsynaptic Spines: A New Therapeutic Target for Alzheimer's Disease Treatment.Network-wide dysregulation of calcium homeostasis in Alzheimer's disease.Sense and specificity in neuronal calcium signalling.Dantrolene, a treatment for Alzheimer disease?Post-translational remodeling of ryanodine receptor induces calcium leak leading to Alzheimer's disease-like pathologies and cognitive deficits.Twenty Years of Presenilins--Important Proteins in Health and Disease.Dysregulation of neuronal calcium homeostasis in Alzheimer's disease - A therapeutic opportunity?Emerging pathways driving early synaptic pathology in Alzheimer's disease.Basis for a neuronal version of Grover's quantum algorithm.Endoplasmic Reticulum Malfunction in the Nervous System.Abnormal dendritic calcium activity and synaptic depotentiation occur early in a mouse model of Alzheimer's disease.Knockdown of amyloid precursor protein increases calcium levels in the endoplasmic reticulum.Stim2-Eb3 Association and Morphology of Dendritic Spines in Hippocampal Neurons.Calcium Dysregulation in Alzheimer's Disease: A Target for New Drug Development.Interactions of Mitochondria/Metabolism and Calcium Regulation in Alzheimer's Disease: A Calcinist Point of View.Intracellular Ca2+ stores control in vivo neuronal hyperactivity in a mouse model of Alzheimer's disease.What can computational modeling offer for studying the Ca dysregulation in Alzheimer's disease: current research and future directionsA mathematical model for the effects of amyloid beta on intracellular calcium
P2860
Q30274630-E5EEA89C-A90D-4DE8-8ABD-3A9F29F598ACQ33554241-8E6CFB9D-CEFD-4731-B2B1-B4768C458EA7Q33612558-E45CAFFE-93B8-4A95-9D82-7C9B7A184ACFQ34281322-DED43893-96A2-4B47-8F90-711998B601C6Q34451907-88060060-6AC5-4356-BD85-46636D4830ABQ35484349-EA51DE27-CFA2-4DCA-87E0-02BF4D10561FQ35535117-53443083-E566-41C0-ACC1-99E2C9A3BEEAQ35954470-DB7D5D06-B1CE-4422-B5D7-12931D94F863Q36106832-FB7F1E8D-5F4F-42AE-89CF-1C383B284DDAQ36592065-D62F80D7-DD55-4352-A3D0-09238A9A96E2Q36690758-DE5819FC-C7EC-4A08-AEF3-D6741E7CB31DQ37445085-0BB00EAF-9678-46A0-8AE7-DBAA88059A70Q38189691-DC73E653-C67E-4407-8C87-E6B3482CEC9BQ38275175-FA2E4549-18B1-4CE7-A868-58176D1C9C6EQ38304771-D9D8A70D-E15A-42B8-871F-9E47630A6ECAQ38718079-825E31CC-9899-48E7-B024-5332E47980EDQ38938820-D320D9C3-3C4A-473B-9EEC-F001F84F703DQ38958106-A3B60FF1-00BF-4B1E-8B73-7CF3235FAF6DQ38962140-8941AAB0-47F2-4A95-97CD-1A541A590009Q39821415-44D55DA6-BB8E-40A6-9E58-D413D0F79EF2Q42290598-DFC0AC2A-1E59-4DE0-BE6B-FC994BA89DE3Q45927957-017AA03D-D7EE-4BBE-A9E0-43D1F2CE4FE7Q47109064-EF1D2C94-0F05-48BB-968B-A3B5C4ED59D4Q47109482-85744671-539D-4E92-AFA6-C5A4770665A9Q47928995-466D4DCB-DB3B-4D76-9245-5AF4DF87FF56Q48259154-F830A004-138A-48CD-949D-8F7426C6C55AQ49873932-CF5D56D5-E06D-4C86-8329-0BBDE214C95AQ57178734-FC8BF4DE-BDC6-4D0D-A1D3-BC0BBDECC271Q58722978-B0E066AA-8276-412E-B91C-A6DAB5044D55
P2860
Role of endoplasmic reticulum Ca2+ signaling in the pathogenesis of Alzheimer disease
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 18 September 2013
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Role of endoplasmic reticulum Ca2+ signaling in the pathogenesis of Alzheimer disease
@en
Role of endoplasmic reticulum Ca2+ signaling in the pathogenesis of Alzheimer disease.
@nl
type
label
Role of endoplasmic reticulum Ca2+ signaling in the pathogenesis of Alzheimer disease
@en
Role of endoplasmic reticulum Ca2+ signaling in the pathogenesis of Alzheimer disease.
@nl
prefLabel
Role of endoplasmic reticulum Ca2+ signaling in the pathogenesis of Alzheimer disease
@en
Role of endoplasmic reticulum Ca2+ signaling in the pathogenesis of Alzheimer disease.
@nl
P2860
P921
P356
P1476
Role of endoplasmic reticulum Ca2+ signaling in the pathogenesis of Alzheimer disease
@en
P2093
Elena Popugaeva
Ilya Bezprozvanny
P2860
P356
10.3389/FNMOL.2013.00029
P577
2013-09-18T00:00:00Z