Fission yeast Scm3 mediates stable assembly of Cnp1/CENP-A into centromeric chromatin.
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Dimerization of the CENP-A assembly factor HJURP is required for centromeric nucleosome depositionThe structure of (CENP-A-H4)(2) reveals physical features that mark centromeresThe Lrs4-Csm1 monopolin complex associates with kinetochores during anaphase and is required for accurate chromosome segregationThe kinetochore interaction network (KIN) of ascomycetesDiversity in requirement of genetic and epigenetic factors for centromere function in fungiShearing of the CENP-A dimerization interface mediates plasticity in the octameric centromeric nucleosome.The cell cycle timing of centromeric chromatin assembly in Drosophila meiosis is distinct from mitosis yet requires CAL1 and CENP-CStructural basis for recognition of centromere histone variant CenH3 by the chaperone Scm3Recognition of the centromere-specific histone Cse4 by the chaperone Scm3Identification of Functionally Conserved Regions in the Structure of the Chaperone/CenH3/H4 ComplexCse4 is part of an octameric nucleosome in budding yeast.Histone H3 localizes to the centromeric DNA in budding yeastMisregulation of Scm3p/HJURP causes chromosome instability in Saccharomyces cerevisiae and human cells.Centromere localization and function of Mis18 requires Yippee-like domain-mediated oligomerizationFission yeast Scm3: A CENP-A receptor required for integrity of subkinetochore chromatinThe histone chaperone sNASP binds a conserved peptide motif within the globular core of histone H3 through its TPR repeatsLicensing of Centromeric Chromatin Assembly through the Mis18α-Mis18β Heterotetramer.Putting CENP-A in its placeHJURP uses distinct CENP-A surfaces to recognize and to stabilize CENP-A/histone H4 for centromere assembly.Centromere identity, function, and epigenetic propagation across cell divisions.HJURP is a CENP-A chromatin assembly factor sufficient to form a functional de novo kinetochore.Down the rabbit hole of centromere assembly and dynamics.Scm3 deposits a (Cse4-H4)2 tetramer onto DNA through a Cse4-H4 dimer intermediate.HJURP binds CENP-A via a highly conserved N-terminal domain and mediates its deposition at centromeresImaging the fate of histone Cse4 reveals de novo replacement in S phase and subsequent stable residence at centromeres.Rad3 decorates critical chromosomal domains with gammaH2A to protect genome integrity during S-Phase in fission yeast.The life and miracles of kinetochores.The centromere: chromatin foundation for the kinetochore machinery.Centromeres: unique chromatin structures that drive chromosome segregation.Identification of noncoding transcripts from within CENP-A chromatin at fission yeast centromeres.Factors that promote H3 chromatin integrity during transcription prevent promiscuous deposition of CENP-A(Cnp1) in fission yeastThe octamer is the major form of CENP-A nucleosomes at human centromeres.The CENP-A nucleosome: a dynamic structure and role at the centromere.Eic1 links Mis18 with the CCAN/Mis6/Ctf19 complex to promote CENP-A assemblyOverlapping regulation of CenH3 localization and histone H3 turnover by CAF-1 and HIR proteins in Saccharomyces cerevisiae.Xenopus HJURP and condensin II are required for CENP-A assembly.DNA topoisomerase III localizes to centromeres and affects centromeric CENP-A levels in fission yeast.Epigenetic centromere propagation and the nature of CENP-a nucleosomes.Scm3 is a centromeric nucleosome assembly factorThe centromere: epigenetic control of chromosome segregation during mitosis
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Fission yeast Scm3 mediates stable assembly of Cnp1/CENP-A into centromeric chromatin.
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article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on February 2009
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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Fission yeast Scm3 mediates stable assembly of Cnp1/CENP-A into centromeric chromatin.
@en
Fission yeast Scm3 mediates stable assembly of Cnp1/CENP-A into centromeric chromatin.
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label
Fission yeast Scm3 mediates stable assembly of Cnp1/CENP-A into centromeric chromatin.
@en
Fission yeast Scm3 mediates stable assembly of Cnp1/CENP-A into centromeric chromatin.
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prefLabel
Fission yeast Scm3 mediates stable assembly of Cnp1/CENP-A into centromeric chromatin.
@en
Fission yeast Scm3 mediates stable assembly of Cnp1/CENP-A into centromeric chromatin.
@nl
P2093
P2860
P1433
P1476
Fission yeast Scm3 mediates stable assembly of Cnp1/CENP-A into centromeric chromatin.
@en
P2093
Jessica S Williams
Mitsuhiro Yanagida
Paul Russell
Takeshi Hayashi
P2860
P304
P356
10.1016/J.MOLCEL.2009.01.017
P577
2009-02-01T00:00:00Z