pH sensing by FAK-His58 regulates focal adhesion remodeling
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FAK in cancer: mechanistic findings and clinical applicationsElectrochemical regulation of budding yeast polarityProlactin Signaling Stimulates Invasion via Na(+)/H(+) Exchanger NHE1 in T47D Human Breast Cancer CellsTalin regulates moesin-NHE-1 recruitment to invadopodia and promotes mammary tumor metastasis.Increased H⁺ efflux is sufficient to induce dysplasia and necessary for viability with oncogene expression.Acidic pH and divalent cation sensing by PhoQ are dispensable for systemic salmonellae virulence.Phospholipid binding to the FAK catalytic domain impacts function.pHocal adhesion kinase regulation is on a FERM foundation.Increased intracellular pH is necessary for adult epithelial and embryonic stem cell differentiation.Inhibition of endothelial FAK activity prevents tumor metastasis by enhancing barrier function.Talin-bound NPLY motif recruits integrin-signaling adapters to regulate cell spreading and mechanosensing.A Histidine Cluster in the Cytoplasmic Domain of the Na-H Exchanger NHE1 Confers pH-sensitive Phospholipid Binding and Regulates Transporter Activity.Effects and mechanism of flavonoids from Astragalus complanatus on breast cancer growth.Cancer cell behaviors mediated by dysregulated pH dynamics at a glance.Focal adhesion kinase signaling in unexpected places.Prominent features of the amino acid mutation landscape in cancer.A Histidine pH sensor regulates activation of the Ras-specific guanine nucleotide exchange factor RasGRP1.Cancer-associated arginine-to-histidine mutations confer a gain in pH sensing to mutant proteins.Methods for Imaging Intracellular pH of the Follicle Stem Cell Lineage in Live Drosophila Ovarian Tissue.Influence of acidic pH on keratinocyte function and re-epithelialisation of human in vitro wounds.Targeting Focal Adhesion Kinase Using Inhibitors of Protein-Protein Interactions
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P2860
pH sensing by FAK-His58 regulates focal adhesion remodeling
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
@pt
bilimsel makale
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scientific article published on September 2013
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
pH sensing by FAK-His58 regulates focal adhesion remodeling
@en
pH sensing by FAK-His58 regulates focal adhesion remodeling.
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type
label
pH sensing by FAK-His58 regulates focal adhesion remodeling
@en
pH sensing by FAK-His58 regulates focal adhesion remodeling.
@nl
prefLabel
pH sensing by FAK-His58 regulates focal adhesion remodeling
@en
pH sensing by FAK-His58 regulates focal adhesion remodeling.
@nl
P2093
P2860
P356
P1476
pH sensing by FAK-His58 regulates focal adhesion remodeling
@en
P2093
Bradley A Webb
Chang-Hoon Choi
Diane L Barber
Michael S Chimenti
P2860
P304
P356
10.1083/JCB.201302131
P407
P577
2013-09-01T00:00:00Z