Differing roles for members of the phospholipase A2 superfamily in experimental autoimmune encephalomyelitis.
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Role of prostaglandins in neuroinflammatory and neurodegenerative diseasesPhospholipase A2 enzymes: physical structure, biological function, disease implication, chemical inhibition, and therapeutic interventionCysteinyl Leukotrienes and Their Receptors: Emerging Therapeutic Targets in Central Nervous System DisordersInsertion of the Ca²⁺-independent phospholipase A₂ into a phospholipid bilayer via coarse-grained and atomistic molecular dynamics simulationsCharacterization of FKGK18 as inhibitor of group VIA Ca2+-independent phospholipase A2 (iPLA2β): candidate drug for preventing beta-cell apoptosis and diabetesGroup V Secretory Phospholipase A2 Is Involved in Tubular Integrity and Sodium Handling in the KidneyDysregulation of lysophosphatidic acids in multiple sclerosis and autoimmune encephalomyelitis.Potent and selective fluoroketone inhibitors of group VIA calcium-independent phospholipase A2.Cerebrospinal fluid secretory Ca2+-dependent phospholipase A2 activity: a biomarker of blood-cerebrospinal fluid barrier permeability.Purification and characterization of a cytosolic Ca(2+)-independent phospholipase A(2) from bovine brain.Role of cytosolic phospholipase A2 in oxidative and inflammatory signaling pathways in different cell types in the central nervous systemImaging decreased brain docosahexaenoic acid metabolism and signaling in iPLA(2)β (VIA)-deficient mice.Inhibition of Ca2+-independent phospholipase A2β (iPLA2β) ameliorates islet infiltration and incidence of diabetes in NOD mice.Time-dependent changes in the brain arachidonic acid cascade during cuprizone-induced demyelination and remyelination.Inhibition of 5-lipoxygenase activity in mice during cuprizone-induced demyelination attenuates neuroinflammation, motor dysfunction and axonal damageCombination therapy of an inhibitor of group VIA phospholipase A2 with paclitaxel is highly effective in blocking ovarian cancer developmentPhospholipase A2 superfamily members play divergent roles after spinal cord injury.Calcium-independent phospholipases A2 and their roles in biological processes and diseases.Profile of Circulatory Metabolites in a Relapsing-remitting Animal Model of Multiple Sclerosis using Global Metabolomics.Liberating Chiral Lipid Mediators, Inflammatory Enzymes, and LIPID MAPS from Biological Grease.New potent and selective polyfluoroalkyl ketone inhibitors of GVIA calcium-independent phospholipase A2.Molecular and immunogenic features of myelin lipids: incitants or modulators of multiple sclerosis?Phospholipases A2 and inflammatory responses in the central nervous system.Phospholipase A2 inhibitors as potential therapeutic agents for the treatment of inflammatory diseases.Protective effect of cytosolic phospholipase A2 inhibition against inflammation and degeneration by promoting regulatory T cells in rats with experimental autoimmune encephalomyelitis.Role of phospholipase A2s and lipid mediators in secondary damage after spinal cord injury.Role of cytosolic calcium-dependent phospholipase A2 in Alzheimer's disease pathogenesis.Phospholipase A2 inhibitors for the treatment of inflammatory diseases: a patent review (2010--present).Analyses of Calcium-Independent Phospholipase A2beta (iPLA2β) in Biological Systems.Cysteinyl Leukotrienes as Potential Pharmacological Targets for Cerebral Diseases.Fluoroketone inhibition of Ca(2+)-independent phospholipase A2 through binding pocket association defined by hydrogen/deuterium exchange and molecular dynamics.2-Oxoamides based on dipeptides as selective calcium-independent phospholipase A2 inhibitors.Mechanisms of lysophosphatidylcholine-induced demyelination: A primary lipid disrupting myelinopathy.The structure of iPLA2β reveals dimeric active sites and suggests mechanisms of regulation and localization.
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Differing roles for members of the phospholipase A2 superfamily in experimental autoimmune encephalomyelitis.
description
article científic
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article scientifique
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articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 13 February 2009
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
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name
Differing roles for members of ...... autoimmune encephalomyelitis.
@en
Differing roles for members of ...... autoimmune encephalomyelitis.
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type
label
Differing roles for members of ...... autoimmune encephalomyelitis.
@en
Differing roles for members of ...... autoimmune encephalomyelitis.
@nl
prefLabel
Differing roles for members of ...... autoimmune encephalomyelitis.
@en
Differing roles for members of ...... autoimmune encephalomyelitis.
@nl
P2093
P2860
P50
P356
P1433
P1476
Differing roles for members of ...... l autoimmune encephalomyelitis
@en
P2093
Athena Kalyvas
Constantinos Baskakis
Daren Stephens
George Kokotos
Samuel David
V Wee Yong
Violetta Constantinou-Kokotou
P2860
P304
P356
10.1093/BRAIN/AWP002
P407
P577
2009-02-13T00:00:00Z