Sapacitabine, the prodrug of CNDAC, is a nucleoside analog with a unique action mechanism of inducing DNA strand breaks
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Mechanism-Based Drug Combinations with the DNA Strand-Breaking Nucleoside Analog CNDAC.DNA polymerase θ specializes in incorporating synthetic expanded-size (xDNA) nucleotidesNovel drugs for older patients with acute myeloid leukemia.TDP1 is critical for the repair of DNA breaks induced by sapacitabine, a nucleoside also targeting ATM- and BRCA-deficient tumors.Genetics educational needs in China: physicians' experience and knowledge of genetic testing.Targeting BRCA1/2 deficient ovarian cancer with CNDAC-based drug combinations.
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Sapacitabine, the prodrug of CNDAC, is a nucleoside analog with a unique action mechanism of inducing DNA strand breaks
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article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 26 June 2012
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Sapacitabine, the prodrug of C ...... of inducing DNA strand breaks
@en
Sapacitabine, the prodrug of C ...... of inducing DNA strand breaks.
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type
label
Sapacitabine, the prodrug of C ...... of inducing DNA strand breaks
@en
Sapacitabine, the prodrug of C ...... of inducing DNA strand breaks.
@nl
prefLabel
Sapacitabine, the prodrug of C ...... of inducing DNA strand breaks
@en
Sapacitabine, the prodrug of C ...... of inducing DNA strand breaks.
@nl
P2093
P2860
P356
P1476
Sapacitabine, the prodrug of C ...... of inducing DNA strand breaks
@en
P2093
Billie Nowak
William Plunkett
Xiao-Jun Liu
Ya-Qing Wang
P2860
P304
P356
10.5732/CJC.012.10077
P577
2012-06-26T00:00:00Z