Direct effects, compensation, and recovery in female fathead minnows exposed to a model aromatase inhibitor
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Dietary exposure of 17-alpha ethinylestradiol modulates physiological endpoints and gene signaling pathways in female largemouth bass (Micropterus salmoides).Triclosan impairs swimming behavior and alters expression of excitation-contraction coupling proteins in fathead minnow (Pimephales promelas).Leveraging existing data for prioritization of the ecological risks of human and veterinary pharmaceuticals to aquatic organisms.Fathead minnow steroidogenesis: in silico analyses reveals tradeoffs between nominal target efficacy and robustness to cross-talk.Use of gene expression, biochemical and metabolite profiles to enhance exposure and effects assessment of the model androgen 17β-trenbolone in fish.Mice lacking Mrp1 have reduced testicular steroid hormone levels and alterations in steroid biosynthetic enzymesFutureTox II: in vitro data and in silico models for predictive toxicologyAffinity and matrix effects in measuring fish plasma vitellogenin using immunosorbent assays: considerations for aquatic toxicologists.Human and ecological risk assessment of a crop protection chemical: a case study with the azole fungicide epoxiconazole.Omics for aquatic ecotoxicology: control of extraneous variability to enhance the analysis of environmental effects.A review of the effects of azole compounds in fish and their possible involvement in masculinization of wild fish populations.Challenges in assigning endocrine-specific modes of action: Recommendations for researchers and regulators.Temporal changes in biological responses and uncertainty in assessing risks of endocrine-disrupting chemicals: insights from intensive time-course studies with fish.Predicting chemical impacts on vertebrate endocrine systems.Quantitative Adverse Outcome Pathways and Their Application to Predictive Toxicology.Rapid effects of the aromatase inhibitor fadrozole on steroid production and gene expression in the ovary of female fathead minnows (Pimephales promelas).Prioritization of Contaminants of Emerging Concern in Wastewater Treatment Plant Discharges Using Chemical:Gene Interactions in Caged Fish.Editor's Highlight: Computational Modeling of Plasma Vitellogenin Alterations in Response to Aromatase Inhibition in Fathead Minnows.Adverse outcome pathways: a concise introduction for toxicologists.Temporal evaluation of effects of a model 3β-hydroxysteroid dehydrogenase inhibitor on endocrine function in the fathead minnow.
P2860
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P2860
Direct effects, compensation, and recovery in female fathead minnows exposed to a model aromatase inhibitor
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 12 December 2008
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
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vědecký článek
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name
Direct effects, compensation, ...... to a model aromatase inhibitor
@en
Direct effects, compensation, ...... o a model aromatase inhibitor.
@nl
type
label
Direct effects, compensation, ...... to a model aromatase inhibitor
@en
Direct effects, compensation, ...... o a model aromatase inhibitor.
@nl
prefLabel
Direct effects, compensation, ...... to a model aromatase inhibitor
@en
Direct effects, compensation, ...... o a model aromatase inhibitor.
@nl
P2093
P2860
P356
P1476
Direct effects, compensation, ...... to a model aromatase inhibitor
@en
P2093
Dalma Martinović
Daniel L Villeneuve
David Bencic
Elizabeth A Makynen
Elizabeth J Durhan
Gerald T Ankley
Jenna E Cavallin
Kathleen M Jensen
Michael D Kahl
Nathaniel D Mueller
P2860
P304
P356
10.1289/EHP.11891
P577
2008-12-12T00:00:00Z