HERV-K(HML-2), the Best Preserved Family of HERVs: Endogenization, Expression, and Implications in Health and Disease.
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Expression of evolutionarily novel genes in tumorsHistorical review of the causes of cancerInside the Envelope: Endogenous Retrovirus-K Env as a Biomarker and Therapeutic TargetEndogenous retroviral promoter exaptation in human cancerTemplated Sequence Insertion Polymorphisms in the Human GenomeAre human endogenous retroviruses triggers of autoimmune diseases? Unveiling associations of three diseases and viral lociIdentification and spontaneous immune targeting of an endogenous retrovirus K envelope protein in the Indian rhesus macaque model of human diseaseU6 snRNA Pseudogenes: Markers of Retrotransposition Dynamics in MammalsThe effect of life history on retroviral genome invasionsImpacts of endogenous retroviruses on tumorigenesis, immunity, stem cells, and research safetyMining for viral fragments in methylation enriched sequencing data.Friends-Enemies: Endogenous Retroviruses Are Major Transcriptional Regulators of Human DNAA human endogenous retrovirus-derived gene that can contribute to oncogenesis by activating the ERK pathway and inducing migration and invasionElevated HERV-K mRNA expression in PBMC is associated with a prostate cancer diagnosis particularly in older men and smokersDistinct isoform of FABP7 revealed by screening for retroelement-activated genes in diffuse large B-cell lymphoma.Intrinsic retroviral reactivation in human preimplantation embryos and pluripotent cells.HERV-K(HML-2), a seemingly silent subtenant - but still waters run deep.The HERV-K human endogenous retrovirus envelope protein antagonizes Tetherin antiviral activityTranscriptional activity of human endogenous retroviruses in human peripheral blood mononuclear cells.HERV-K(HML-2) rec and np9 transcripts not restricted to disease but present in many normal human tissues.Differential expression of HERV-K (HML-2) proviruses in cells and virions of the teratocarcinoma cell line Tera-1.Genome-wide amplification of proviral sequences reveals new polymorphic HERV-K(HML-2) proviruses in humans and chimpanzees that are absent from genome assemblies.Human endogenous retroviruses sustain complex and cooperative regulation of gene-containing loci and unannotated megabase-sized regions.Human Endogenous Retrovirus Type K (HERV-K) Particles Package and Transmit HERV-K-Related SequencesChimeric antigen receptor T cells targeting HERV-K inhibit breast cancer and its metastasis through downregulation of RasNew bioinformatic tool for quick identification of functionally relevant endogenous retroviral inserts in human genome.Discovery of unfixed endogenous retrovirus insertions in diverse human populations.Age-related reduction of antibody response against the human endogenous retrovirus K envelope in womenLessons Learned from Mouse Mammary Tumor Virus in Animal Models.Trans-activation, post-transcriptional maturation, and induction of antibodies to HERV-K (HML-2) envelope transmembrane protein in HIV-1 infection.Human Endogenous Retroviruses-K (HML-2) Expression Is Correlated with Prognosis and Progress of Hepatocellular Carcinoma.HERV-K activation is strictly required to sustain CD133+ melanoma cells with stemness features.Viruses as potential pathogenic agents in systemic lupus erythematosus.Down-regulation of human endogenous retrovirus type K (HERV-K) viral env RNA in pancreatic cancer cells decreases cell proliferation and tumor growth.Utility of next-generation RNA-sequencing in identifying chimeric transcription involving human endogenous retroviruses.Determination of Sequences Required for Human Endogenous Retrovirus K Transduction and Its Recognition by Foreign Retroviral Virions.The WTX Tumor Suppressor Interacts with the Transcriptional Corepressor TRIM28.ERVK polyprotein processing and reverse transcriptase expression in human cell line models of neurological disease.The impact of transposable elements on mammalian development.Making a virtue of necessity: the pleiotropic role of human endogenous retroviruses in cancer.
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HERV-K(HML-2), the Best Preserved Family of HERVs: Endogenization, Expression, and Implications in Health and Disease.
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 20 September 2013
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
HERV-K(HML-2), the Best Preser ...... cations in Health and Disease.
@en
HERV-K(HML-2), the Best Preser ...... cations in Health and Disease.
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type
label
HERV-K(HML-2), the Best Preser ...... cations in Health and Disease.
@en
HERV-K(HML-2), the Best Preser ...... cations in Health and Disease.
@nl
prefLabel
HERV-K(HML-2), the Best Preser ...... cations in Health and Disease.
@en
HERV-K(HML-2), the Best Preser ...... cations in Health and Disease.
@nl
P2093
P2860
P356
P1476
HERV-K(HML-2), the Best Preser ...... cations in Health and Disease.
@en
P2093
Kirsten Hanke
Norbert Bannert
Oliver Hohn
P2860
P356
10.3389/FONC.2013.00246
P577
2013-09-20T00:00:00Z