Genetic predisposition to breast cancer: past, present, and future.
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Breast cancer-associated missense mutants of the PALB2 WD40 domain, which directly binds RAD51C, RAD51 and BRCA2, disrupt DNA repairScreening and association testing of common coding variation in steroid hormone receptor co-activator and co-repressor genes in relation to breast cancer risk: the Multiethnic CohortExomic sequencing identifies PALB2 as a pancreatic cancer susceptibility geneCellular response to DNA interstrand crosslinks: the Fanconi anemia pathwayRepair of strand breaks by homologous recombinationRANKL/RANK: from bone loss to the prevention of breast cancerGermline mutations in RAD51D confer susceptibility to ovarian cancerMosaic PPM1D mutations are associated with predisposition to breast and ovarian cancerHsp90-dependent assembly of the DBC2/RhoBTB2-Cullin3 E3-ligase complexRare mutations in XRCC2 increase the risk of breast cancerNovel germline PALB2 truncating mutations in African American breast cancer patientsExpanded roles of the Fanconi anemia pathway in preserving genomic stabilityEstablished and Suspected Risk Factors in Breast Cancer Aetiology.AluY-mediated germline deletion, duplication and somatic stem cell reversion in UBE2T defines a new subtype of Fanconi anemia.Exome sequencing of germline DNA from non-BRCA1/2 familial breast cancer cases selected on the basis of aCGH tumor profiling.Sequencing analysis of SLX4/FANCP gene in Italian familial breast cancer cases.Hereditary breast cancer: ever more pieces to the polygenic puzzle.Genetic mechanisms in Apc-mediated mammary tumorigenesisMutation analysis of the AATF gene in breast cancer families.Case-control analysis of truncating mutations in DNA damage response genes connects TEX15 and FANCD2 with hereditary breast cancer susceptibility.Mutagen sensitivity, tobacco smoking and breast cancer risk: a case-control study.Functional deficiency of NBN, the Nijmegen breakage syndrome protein, in a p.R215W mutant breast cancer cell line.Gene-gene interactions in breast cancer susceptibility.Chk2*1100delC Acts in synergy with the Ron receptor tyrosine kinase to accelerate mammary tumorigenesis in mice.Identification of Novel Susceptibility Genes for Breast Cancer - Genome-Wide Association Studies or Evaluation of Candidate Genes?Breast cancer susceptibility: current knowledge and implications for genetic counsellingFGFR2 and other loci identified in genome-wide association studies are associated with breast cancer in African-American and younger women.Poly (ADP-ribose) polymerase as a novel therapeutic target in cancer.Inactivating Mutations in GT198 in Familial and Early-Onset Breast and Ovarian Cancers.A study on genetic variants of Fibroblast growth factor receptor 2 (FGFR2) and the risk of breast cancer from North IndiaSingle nucleotide polymorphisms in noncoding regions of Rad51C do not change the risk of unselected breast cancer but they modulate the level of oxidative stress and the DNA damage characteristics: a case-control study.Validation of the cell cycle G(2) delay assay in assessing ionizing radiation sensitivity and breast cancer risk.Hereditary breast cancer: clinical, pathological and molecular characteristics.Association of germline variation in CCNE1 and CDK2 with breast cancer risk, progression and survival among Chinese Han womenRAD51C--a new human cancer susceptibility gene for sporadic squamous cell carcinoma of the head and neck (HNSCC).The risk allele of SNP rs3803662 and the mRNA level of its closest genes TOX3 and LOC643714 predict adverse outcome for breast cancer patientsOwnership of uncertainty: healthcare professionals counseling and treating women from hereditary breast and ovarian cancer families who receive an inconclusive BRCA1/2 genetic test resultAssessment of SLX4 Mutations in Hereditary Breast Cancers.Upregulation of Poly (ADP-Ribose) Polymerase-1 (PARP1) in Triple-Negative Breast Cancer and Other Primary Human Tumor Types.Hereditary breast and ovarian cancer: new genes, new treatments, new concepts.
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P2860
Genetic predisposition to breast cancer: past, present, and future.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on January 2008
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
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name
Genetic predisposition to breast cancer: past, present, and future.
@en
Genetic predisposition to breast cancer: past, present, and future.
@nl
type
label
Genetic predisposition to breast cancer: past, present, and future.
@en
Genetic predisposition to breast cancer: past, present, and future.
@nl
prefLabel
Genetic predisposition to breast cancer: past, present, and future.
@en
Genetic predisposition to breast cancer: past, present, and future.
@nl
P1476
Genetic predisposition to breast cancer: past, present, and future.
@en
P304
P356
10.1146/ANNUREV.GENOM.9.081307.164339
P577
2008-01-01T00:00:00Z