Bufalin suppresses hepatocellular carcinoma invasion and metastasis by targeting HIF-1α via the PI3K/AKT/mTOR pathway.
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Selective Pro-Apoptotic Activity of Novel 3,3'-(Aryl/Alkyl-Methylene)Bis(2-Hydroxynaphthalene-1,4-Dione) Derivatives on Human Cancer Cells via the Induction Reactive Oxygen SpeciesEmploying an orthotopic model to study the role of epithelial-mesenchymal transition in bladder cancer metastasisSpermidine/spermine N1-acetyltransferase regulates cell growth and metastasis via AKT/β-catenin signaling pathways in hepatocellular and colorectal carcinoma cells.Hypoxia inducible factors in hepatocellular carcinomaDifferential pattern of HIF-1α expression in HNSCC cancer stem cells after carbon ion or photon irradiation: one molecular explanation of the oxygen effect.Bufalin reverses ABCB1-mediated drug resistance in colorectal cancer.Tetrahydrocurcumin induces mesenchymal-epithelial transition and suppresses angiogenesis by targeting HIF-1α and autophagy in human osteosarcoma.Novel augmentation by bufalin of protein kinase C-induced cyclooxygenase-2 and IL-8 production in human breast cancer cells.Actinidia callosa var. callosa suppresses metastatic potential of human hepatoma cell SK-Hep1 by inhibiting matrix metalloproteinase-2 through PI3K/Akt and MAPK signaling pathways.Aurora-A Regulates Progression and Metastasis of Colorectal Cancer by Promoting Slug Activity.Oridonin inhibits migration, invasion, adhesion and TGF-β1-induced epithelial-mesenchymal transition of melanoma cells by inhibiting the activity of PI3K/Akt/GSK-3β signaling pathway.MiR-646 inhibited cell proliferation and EMT-induced metastasis by targeting FOXK1 in gastric cancer.Cardiac glycoside bufalin blocks cancer cell growth by inhibition of Aurora A and Aurora B activation via PI3K-Akt pathway.Synergistic anticancer effects of bufalin and sorafenib by regulating apoptosis associated proteins.Bufalin induces DNA damage response under hypoxic condition in myeloma cells.Bufalin suppresses hepatocarcinogenesis by targeting β-catenin/TCF signaling via cell cycle-related kinase.Bufalin Suppresses Migration and Invasion of Hepatocellular Carcinoma Cells Elicited by Poly (I:C) Therapy.HIF1α-dependent glycolysis promotes macrophage functional activities in protecting against bacterial and fungal infection.WWOX controls hepatic HIF1α to suppress hepatocyte proliferation and neoplasia.Molecular mechanisms underlying the antimetastatic activity of bufalin.Bufalin inhibits gastric cancer invasion and metastasis by down-regulating Wnt/ASCL2 expression.Long non-coding RNA UBE2CP3 enhances HCC cell secretion of VEGFA and promotes angiogenesis by activating ERK1/2/HIF-1α/VEGFA signalling in hepatocellular carcinoma.Telocinobufagin and Marinobufagin Produce Different Effects in LLC-PK1 Cells: A Case of Functional Selectivity of BufadienolidesThe Chinese Medicine, Jiedu Recipe, Inhibits the Epithelial Mesenchymal Transition of Hepatocellular Carcinoma via the Regulation of Smad2/3 Dependent and Independent Pathways
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Bufalin suppresses hepatocellular carcinoma invasion and metastasis by targeting HIF-1α via the PI3K/AKT/mTOR pathway.
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article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 06 March 2016
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Bufalin suppresses hepatocellu ...... via the PI3K/AKT/mTOR pathway.
@en
Bufalin suppresses hepatocellu ...... via the PI3K/AKT/mTOR pathway.
@nl
type
label
Bufalin suppresses hepatocellu ...... via the PI3K/AKT/mTOR pathway.
@en
Bufalin suppresses hepatocellu ...... via the PI3K/AKT/mTOR pathway.
@nl
prefLabel
Bufalin suppresses hepatocellu ...... via the PI3K/AKT/mTOR pathway.
@en
Bufalin suppresses hepatocellu ...... via the PI3K/AKT/mTOR pathway.
@nl
P2093
P2860
P356
P1433
P1476
Bufalin suppresses hepatocellu ...... via the PI3K/AKT/mTOR pathway.
@en
P2093
Chenyue Zhang
Feng Jiang
Haiyong Wang
Huiying Chi
Xiaoyan Zhu
Zhiqiang Meng
Zhouyu Ning
P2860
P304
20193-20208
P356
10.18632/ONCOTARGET.7935
P407
P577
2016-03-06T00:00:00Z