PDX1 in ducts is not required for postnatal formation of β-cells but is necessary for their subsequent maturation. - Wikidata - awgldk - TriplyDB

PDX1 in ducts is not required for postnatal formation of β-cells but is necessary for their subsequent maturation.

PDX1 in ducts is not required for postnatal formation of β-cells but is necessary for their subsequent maturation.

http://www.wikidata.org/entity/Q37193305

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Human β-cell regeneration: progress, hurdles, and controversy.TCF2 attenuates FFA-induced damage in islet β-cells by regulating production of insulin and ROS.Vitamin A deficiency causes hyperglycemia and loss of pancreatic β-cell mass.Reprogramming Mouse Cells With a Pancreatic Duct Phenotype to Insulin-Producing β-Like Cells Pdx1 regulates pancreas tubulogenesis and E-cadherin expression.Dynamic development of the pancreas from birth to adulthood.V-Maf Musculoaponeurotic Fibrosarcoma Oncogene Homolog A Synthetic Modified mRNA Drives Reprogramming of Human Pancreatic Duct-Derived Cells Into Insulin-Secreting Cells An increase in immature β-cells lacking Glut2 precedes the expansion of β-cell mass in the pregnant mouse.Heterogeneity of SOX9 and HNF1β in Pancreatic Ducts Is Dynamic.

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PDX1 in ducts is not required for postnatal formation of β-cells but is necessary for their subsequent maturation.

http://www.wikidata.org/entity/Q37193305

description

article científic

@ca

article scientifique

@fr

articolo scientifico

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artigo científico

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bilimsel makale

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scientific article published on 17 June 2013

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vedecký článok

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vetenskaplig artikel

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videnskabelig artikel

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vědecký článek

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name

PDX1 in ducts is not required ...... r their subsequent maturation.

@en

PDX1 in ducts is not required ...... r their subsequent maturation.

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type

label

PDX1 in ducts is not required ...... r their subsequent maturation.

@en

PDX1 in ducts is not required ...... r their subsequent maturation.

@nl

prefLabel

PDX1 in ducts is not required ...... r their subsequent maturation.

@en

PDX1 in ducts is not required ...... r their subsequent maturation.

@nl

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PDX1 in ducts is not required ...... r their subsequent maturation.

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Akari Inada

http://www.w3.org/2001/XMLSchema#string

Arun Sharma

http://www.w3.org/2001/XMLSchema#string

Christopher V E Wright

http://www.w3.org/2001/XMLSchema#string

Cristina Aguayo-Mazzucato

http://www.w3.org/2001/XMLSchema#string

Gordon C Weir

http://www.w3.org/2001/XMLSchema#string

Jennifer Hollister-Lock

http://www.w3.org/2001/XMLSchema#string

Lili Guo

http://www.w3.org/2001/XMLSchema#string

Susan Bonner-Weir

http://www.w3.org/2001/XMLSchema#string

Yoshio Fujitani

http://www.w3.org/2001/XMLSchema#string

P2860

pdx-1 function is specifically required in embryonic beta cells to generate appropriate numbers of endocrine cell types and maintain glucose homeostasis

Exendin-4 stimulates both beta-cell replication and neogenesis, resulting in increased beta-cell mass and improved glucose tolerance in diabetic rats

The homeodomain protein PDX1 is required at mid-pancreatic development for the formation of the exocrine pancreas

Pancreatic beta cells require NeuroD to achieve and maintain functional maturity

PDX-1 is required for pancreatic outgrowth and differentiation of the rostral duodenum

Insulin-promoter-factor 1 is required for pancreas development in mice

Restructuring of pancreatic islets and insulin secretion in a postnatal critical window.

Rat neonatal beta cells lack the specialised metabolic phenotype of mature beta cells.

Beta cell mass and growth after syngeneic islet cell transplantation in normal and streptozocin diabetic C57BL/6 mice.

Pancreatic beta cells synthesize neuropeptide Y and can rapidly release peptide co-transmitters

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3459-3468

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scholarly article

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10.2337/DB12-1833

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2013-06-17T00:00:00Z

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