Cytochrome P-450. Multiplicity of isoforms, substrates, and catalytic and regulatory mechanisms.
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Toxic hepatitis in occupational exposure to solventsThe lithocholic acid 6 beta-hydroxylase cytochrome P-450, CYP 3A10, is an active catalyst of steroid-hormone 6 beta-hydroxylationChloramphenicol is a potent inhibitor of cytochrome P450 isoforms CYP2C19 and CYP3A4 in human liver microsomesCancer Activation and Polymorphisms of Human Cytochrome P450 1B1Structure of a cytochrome P450-redox partner electron-transfer complexHuman NADPH-P450 oxidoreductase modulates the level of cytochrome P450 CYP2D6 holoprotein via haem oxygenase-dependent and -independent pathwaysToluene and ethylbenzene oxidation by purified naphthalene dioxygenase from Pseudomonas sp. strain NCIB 9816-4Toxicology, structure-function relationship, and human and environmental health impacts of polychlorinated biphenyls: progress and problemsMoonlighting cytochrome P450 monooxygenases.Neurobehavioral abnormalities in a brain-specific NADPH-cytochrome P450 reductase knockout mouse modelSterol 14alpha-demethylase activity in Streptomyces coelicolor A3(2) is associated with an unusual member of the CYP51 gene family.The maize Dwarf3 gene encodes a cytochrome P450-mediated early step in Gibberellin biosynthesis.Comprehensive characterization of cytochrome P450 isozyme selectivity across chemical libraries.Explaining the atypical reaction profiles of heme enzymes with a novel mechanistic hypothesis and kinetic treatmentCross-linking of human cytochrome P450 2B6 to NADPH-cytochrome P450 reductase: Identification of a potential site of interaction.Gene co-expression network analysis identifies porcine genes associated with variation in metabolizing fenbendazole and flunixin meglumine in the liver.The nuclear orphan receptor CAR-retinoid X receptor heterodimer activates the phenobarbital-responsive enhancer module of the CYP2B gene.A quantitative high-throughput 96-well plate fluorescence assay for mechanism-based inactivators of cytochromes P450 exemplified using CYP2B6.CYP2E1 enhances ethanol-induced lipid accumulation but impairs autophagy in HepG2 E47 cellsInactivation of ethanol-inducible cytochrome P450 and other microsomal P450 isozymes by trans-4-hydroxy-2-nonenal, a major product of membrane lipid peroxidation.Effects of frying oil and Houttuynia cordata thunb on xenobiotic-metabolizing enzyme system of rodents.Genomic and transcriptomic analyses of the medicinal fungus Antrodia cinnamomea for its metabolite biosynthesis and sexual development.Suppression of cytochrome p450 reductase enhances long-term hematopoietic stem cell repopulation efficiency in mice.Molecular mechanisms of the microsomal mixed function oxidases and biological and pathological implicationsIdentification of cytochrome P450 oxidoreductase gene variants that are significantly associated with the interindividual variations in warfarin maintenance dose.Enzyme reactivation by hydrogen peroxide in heme-based tryptophan dioxygenaseavnA, a gene encoding a cytochrome P-450 monooxygenase, is involved in the conversion of averantin to averufin in aflatoxin biosynthesis in Aspergillus parasiticus.Cytochrome P450 1B1 and Primary Congenital GlaucomaIdentification and functional characterization of the CYP51 gene from the yeast Xanthophyllomyces dendrorhous that is involved in ergosterol biosynthesisMolecular Characterization and Functional Analysis of Cytochrome b5 Reductase (CBR) Encoding Genes from the Carotenogenic Yeast Xanthophyllomyces dendrorhousIdentification of structural alerts for liver and kidney toxicity using repeated dose toxicity dataHeme coordination of NO in NO synthase.Phenobarbital induction of cytochrome P-450 gene expression.Effect of active site and surface mutations on the reduction potential of yeast cytochrome c peroxidase and spectroscopic properties of the oxidized and reduced enzyme.Expression of truncated forms of liver microsomal P450 cytochromes 2B4 and 2E1 in Escherichia coli: influence of NH2-terminal region on localization in cytosol and membranes.CYP2E1 and oxidative liver injury by alcohol.Mechanism of chloroform-induced renal toxicity: non-involvement of hepatic cytochrome P450-dependent metabolismMolecular cloning of an allene oxide synthase: a cytochrome P450 specialized for the metabolism of fatty acid hydroperoxides.A nuclear factor (NF2d9) that binds to the male-specific P450 (Cyp 2d-9) gene in mouse liver.A STAT factor mediates the sexually dimorphic regulation of hepatic cytochrome P450 3A10/lithocholic acid 6 beta-hydroxylase gene expression by growth hormone.
P2860
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P2860
Cytochrome P-450. Multiplicity of isoforms, substrates, and catalytic and regulatory mechanisms.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on July 1991
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Cytochrome P-450. Multiplicity ...... tic and regulatory mechanisms.
@en
Cytochrome P-450. Multiplicity ...... tic and regulatory mechanisms.
@nl
type
label
Cytochrome P-450. Multiplicity ...... tic and regulatory mechanisms.
@en
Cytochrome P-450. Multiplicity ...... tic and regulatory mechanisms.
@nl
prefLabel
Cytochrome P-450. Multiplicity ...... tic and regulatory mechanisms.
@en
Cytochrome P-450. Multiplicity ...... tic and regulatory mechanisms.
@nl
P1476
Cytochrome P-450. Multiplicity ...... ytic and regulatory mechanisms
@en
P2093
P304
13469-13472
P407
P577
1991-07-01T00:00:00Z