ESR1 Mutations in Circulating Plasma Tumor DNA from Metastatic Breast Cancer Patients.
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Circulating Tumor DNA as Biomarkers for Cancer Detection.Analysis of Paired Primary-Metastatic Hormone-Receptor Positive Breast Tumors (HRPBC) Uncovers Potential Novel Drivers of Hormonal ResistanceKinetics, prognostic and predictive values of ESR1 circulating mutations in metastatic breast cancer patients progressing on aromatase inhibitorPrognostic role of PIK3CA mutations of cell-free DNA in early-stage triple negative breast cancer.Sensitive Detection of Mono- and Polyclonal ESR1 Mutations in Primary Tumors, Metastatic Lesions, and Cell-Free DNA of Breast Cancer Patients.Heterogeneity and clinical significance of ESR1 mutations in ER-positive metastatic breast cancer patients receiving fulvestrant.Metastatic Breast Cancer With ESR1 Mutation: Clinical Management Considerations From the Molecular and Precision Medicine (MAP) Tumor Board at Massachusetts General HospitalERα-XPO1 Cross Talk Controls Tamoxifen Sensitivity in Tumors by Altering ERK5 Cellular Localization.Clinical significance of monitoring ESR1 mutations in circulating cell-free DNA in estrogen receptor positive breast cancer patients.Clinical Implications of ESR1 Mutations in Hormone Receptor-Positive Advanced Breast CancerDetection fidelity of AR mutations in plasma derived cell-free DNACorrelation between PIK3CA mutations in cell-free DNA and everolimus efficacy in HR+, HER2- advanced breast cancer: results from BOLERO-2.Adamantyl Antiestrogens with Novel Side Chains Reveal a Spectrum of Activities in Suppressing Estrogen Receptor Mediated Activities in Breast Cancer Cells.Comparison of ESR1 Mutations in Tumor Tissue and Matched Plasma Samples from Metastatic Breast Cancer Patients.Cell-free circulating tumour DNA as a liquid biopsy in breast cancer.Development of a gene panel for next-generation sequencing of clinically relevant mutations in cell-free DNA from cancer patients.Catalog of genetic progression of human cancers: breast cancer.Pathologic diagnosis of breast cancer patients: evolution of the traditional clinical-pathologic paradigm toward "precision" cancer therapy.Estrogen receptors in breast and bone: from virtue of remodeling to vileness of metastasis.Liquid biopsy: unlocking the potentials of cell-free DNA.Platelet RNA signatures for the detection of cancer.Heterogeneous estrogen receptor expression in circulating tumor cells suggests diverse mechanisms of fulvestrant resistance.Highly personalized detection of minimal Ewing sarcoma disease burden from plasma tumor DNA.Detection of ESR1 mutations in circulating cell-free DNA from patients with metastatic breast cancer treated with palbociclib and letrozole.Estrogen receptor mutations and splice variants determined in liquid biopsies from metastatic breast cancer patients.Cell-Free DNA in Oncology: Gearing up for Clinic.Prevalence of ESR1 E380Q mutation in tumor tissue and plasma from Japanese breast cancer patients.Mutational profiles of breast cancer metastases from a rapid autopsy series reveal multiple evolutionary trajectories.Hybrid capture-based genomic profiling of circulating tumor DNA from patients with estrogen receptor-positive metastatic breast cancer.Comprehensive mutation and copy number profiling in archived circulating breast cancer tumor cells documents heterogeneous resistance mechanisms.Structurally Novel Antiestrogens Elicit Differential Responses from Constitutively Active Mutant Estrogen Receptors in Breast Cancer Cells and Tumors.Liquid Biopsy in Clinical Management of Breast, Lung, and Colorectal Cancer.Clinically Observed Estrogen Receptor Alpha Mutations within the Ligand-Binding Domain Confer Distinguishable Phenotypes.New Strategies in Metastatic Hormone Receptor-Positive Breast Cancer: Searching for Biomarkers to Tailor Endocrine and Other Targeted Therapies.Individualized Molecular Analyses Guide Efforts (IMAGE): A Prospective Study of Molecular Profiling of Tissue and Blood in Metastatic Triple-Negative Breast Cancer.High-sensitivity assay for monitoring ESR1 mutations in circulating cell-free DNA of breast cancer patients receiving endocrine therapy.Precision Medicine in Hormone Receptor-Positive Breast Cancer.Biotinylated amplicon sequencing: A method for preserving DNA samples of limited quantityUnraveling the clinicopathological features driving the emergence of mutations in metastatic breast cancer
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ESR1 Mutations in Circulating Plasma Tumor DNA from Metastatic Breast Cancer Patients.
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article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 10 August 2015
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
ESR1 Mutations in Circulating Plasma Tumor DNA from Metastatic Breast Cancer Patients.
@en
ESR1 Mutations in Circulating Plasma Tumor DNA from Metastatic Breast Cancer Patients.
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type
label
ESR1 Mutations in Circulating Plasma Tumor DNA from Metastatic Breast Cancer Patients.
@en
ESR1 Mutations in Circulating Plasma Tumor DNA from Metastatic Breast Cancer Patients.
@nl
prefLabel
ESR1 Mutations in Circulating Plasma Tumor DNA from Metastatic Breast Cancer Patients.
@en
ESR1 Mutations in Circulating Plasma Tumor DNA from Metastatic Breast Cancer Patients.
@nl
P2093
P2860
P50
P1476
ESR1 Mutations in Circulating Plasma Tumor DNA from Metastatic Breast Cancer Patients.
@en
P2093
Anne Schott
Arielle Medford
Arul M Chinnaiyan
Ben Ho Park
Berry Button
Bracha Erlanger
Christina Gersch
Dan Robinson
Daniel F Hayes
Daniel J Zabransky
P2860
P304
P356
10.1158/1078-0432.CCR-15-0943
P407
P577
2015-08-10T00:00:00Z