Expanding dialogues: from natural autoinducers to non-natural analogues that modulate quorum sensing in Gram-negative bacteria
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Exploiting Quorum Sensing Interfering Strategies in Gram-Negative Bacteria for the Enhancement of Environmental ApplicationsDirect and Propagated Effects of Small Molecules on Protein-Protein Interaction NetworksAlternative strategies for proof-of-principle studies of antibacterial agentsQuorum quenching revisited--from signal decays to signalling confusionBiologically inspired strategies for combating bacterial biofilmsA Strategy for Antagonizing Quorum SensingSmall molecule control of bacterial biofilmsNew and unexpected insights into the modulation of LuxR-type quorum sensing by cyclic dipeptides.A method for selecting cis-acting regulatory sequences that respond to small molecule effectorsEvaluation of a focused library of N-aryl L-homoserine lactones reveals a new set of potent quorum sensing modulatorsEfficient synthesis and evaluation of quorum-sensing modulators using small molecule macroarraysEfficient construction of diketopiperazine macroarrays through a cyclative-cleavage strategy and their evaluation as luminescence inhibitors in the bacterial symbiont Vibrio fischeriSmall molecule macroarray construction via palladium-mediated carbon-carbon bond-forming reactions: highly efficient synthesis and screening of stilbene arrays.Streptococcus sp. in neonatal endotracheal tube biofilms is associated with ventilator-associated pneumonia and enhanced biofilm formation of Pseudomonas aeruginosa PAO1.Potent and selective synthetic modulators of a quorum sensing repressor in Pseudomonas aeruginosa identified from second-generation libraries of N-acylated L-homoserine lactones.Thiolactone modulators of quorum sensing revealed through library design and screening.Design, synthesis, and biological evaluation of abiotic, non-lactone modulators of LuxR-type quorum sensing.Broad spectrum pro-quorum-sensing molecules as inhibitors of virulence in vibrios.Inhibition of the production of the Pseudomonas aeruginosa virulence factor pyocyanin in wild-type cells by quorum sensing autoinducer-mimics.Mutational analysis of the quorum-sensing receptor LasR reveals interactions that govern activation and inhibition by nonlactone ligands.Expedient construction of small molecule macroarrays via sequential palladium- and copper-mediated reactions and their ex situ biological testing.Synthesis and biological evaluation of triazole-containing N-acyl homoserine lactones as quorum sensing modulatorsN-acylated alanine methyl esters (NAMEs) from Roseovarius tolerans, structural analogs of quorum-sensing autoinducers, N-acylhomoserine lactones.Quorum sensing in bacterial species that use degenerate autoinducers can be tuned by using structurally identical non-native ligands.Synthesis and biological evaluation of novel N-α-haloacylated homoserine lactones as quorum sensing modulatorsAttenuation of virulence in pathogenic bacteria using synthetic quorum-sensing modulators under native conditions on plant hostsQuorum sensing activity of Citrobacter amalonaticus L8A, a bacterium isolated from dental plaqueHighly Effective Inhibition of Biofilm Formation by the First Metagenome-Derived AI-2 Quenching EnzymeBactericidal, quorum quenching and anti-biofilm nanofactories: a new niche for nanotechnologists.Interkingdom Responses to Bacterial Quorum Sensing Signals Regulate Frequency and Rate of Nodulation in Legume-Rhizobia Symbiosis.Surface-mediated release of a synthetic small-molecule modulator of bacterial quorum sensing: gradual release enhances activity.Attenuating Staphylococcus aureus virulence gene regulation: a medicinal chemistry perspective.Exploiting quorum sensing to confuse bacterial pathogens.AutA and AutR, Two Novel Global Transcriptional Regulators, Facilitate Avian Pathogenic Escherichia coli Infection.Defining the mode of action of tetramic acid antibacterials derived from Pseudomonas aeruginosa quorum sensing signals.Highly Potent, Chemically Stable Quorum Sensing Agonists for Vibrio Cholerae.Intercellular communication in bacteria.Non-native N-aroyl L-homoserine lactones are potent modulators of the quorum sensing receptor RpaR in Rhodopseudomonas palustrisProductive steps toward an antimicrobial targeting virulence.Active efflux influences the potency of quorum sensing inhibitors in Pseudomonas aeruginosa.
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Expanding dialogues: from natural autoinducers to non-natural analogues that modulate quorum sensing in Gram-negative bacteria
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 02 June 2008
@en
vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Expanding dialogues: from natu ...... sing in Gram-negative bacteria
@en
Expanding dialogues: from natu ...... ing in Gram-negative bacteria.
@nl
type
label
Expanding dialogues: from natu ...... sing in Gram-negative bacteria
@en
Expanding dialogues: from natu ...... ing in Gram-negative bacteria.
@nl
prefLabel
Expanding dialogues: from natu ...... sing in Gram-negative bacteria
@en
Expanding dialogues: from natu ...... ing in Gram-negative bacteria.
@nl
P2093
P2860
P356
P1476
Expanding dialogues: from natu ...... sing in Gram-negative bacteria
@en
P2093
Grant D Geske
Helen E Blackwell
Jennifer C O'Neill
P2860
P304
P356
10.1039/B703021P
P577
2008-06-02T00:00:00Z