Hexokinase-2-mediated aerobic glycolysis is integral to cerebellar neurogenesis and pathogenesis of medulloblastoma - Wikidata - awgldk - TriplyDB

Hexokinase-2-mediated aerobic glycolysis is integral to cerebellar neurogenesis and pathogenesis of medulloblastoma

Hexokinase-2-mediated aerobic glycolysis is integral to cerebellar neurogenesis and pathogenesis of medulloblastoma

http://www.wikidata.org/entity/Q37196742

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Energy metabolism in neurodevelopment and medulloblastoma Application of metabolomics in drug resistant breast cancer research Broad targeting of angiogenesis for cancer prevention and therapy Novel therapeutic targets of tumor metabolism Adaptations of energy metabolism during cerebellar neurogenesis are co-opted in medulloblastoma Therapeutic targeting of replicative immortality Non-invasive metabolic imaging of brain tumours in the era of precision medicine.Dual proteolytic pathways govern glycolysis and immune competence.Role of aerobic glycolysis in genetically engineered mouse models of cancer.Dengue virus induces and requires glycolysis for optimal replication Metabolic circuits in neural stem cells.The Ketogenic Diet Does Not Affect Growth of Hedgehog Pathway Medulloblastoma in Mice.Biased Allele Expression and Aggression in Hybrid Honeybees may be Influenced by Inappropriate Nuclear-Cytoplasmic Signaling.Sonic Hedgehog Signaling Drives Mitochondrial Fragmentation by Suppressing Mitofusins in Cerebellar Granule Neuron Precursors and Medulloblastoma.Overexpression of ErbB2 renders breast cancer cells susceptible to 3-BrPA through the increased dissociation of hexokinase II from mitochondrial outer membrane.AMPK Is Essential to Balance Glycolysis and Mitochondrial Metabolism to Control T-ALL Cell Stress and Survival.Stem cell metabolism in tissue development and aging The energy sensor AMPK regulates Hedgehog signaling in human cells through a unique Gli1 metabolic checkpoint Metabolic reprogramming during neuronal differentiation from aerobic glycolysis to neuronal oxidative phosphorylation A causal link from ALK to hexokinase II overexpression and hyperactive glycolysis in EML4-ALK-positive lung cancer Lin28 and let-7: ancient milestones on the road from pluripotency to neurogenesis.Metabolic restructuring and cell fate conversion.Medulloblastoma development: tumor biology informs treatment decisions The mitochondrial protein CHCHD2 primes the differentiation potential of human induced pluripotent stem cells to neuroectodermal lineages.ATR maintains chromosomal integrity during postnatal cerebellar neurogenesis and is required for medulloblastoma formation.Hexokinase 2 promotes tumor growth and metastasis by regulating lactate production in pancreatic cancer.Druggable glycolytic requirement for Hedgehog-dependent neuronal and medulloblastoma growth Tumor dynamics in response to antiangiogenic therapy with oral metronomic topotecan and pazopanib in neuroblastoma xenografts.The role of Bergmann glial cells in cerebellar development.Cerebellar granule neuron progenitors are the source of Hk2 in the postnatal cerebellum.Pyruvate Kinase Inhibits Proliferation during Postnatal Cerebellar Neurogenesis and Suppresses Medulloblastoma Formation.LncRNA wires up Hippo and Hedgehog signaling to reprogramme glucose metabolism.TAp73 is a marker of glutamine addiction in medulloblastoma.Distinct metabolic programs induced by TGF-β1 and BMP2 in human articular chondrocytes with osteoarthritis.Oxamate, but Not Selective Targeting of LDH-A, Inhibits Medulloblastoma Cell Glycolysis, Growth and Motility.Aerobic Glycolysis Is Essential for Normal Rod Function and Controls Secondary Cone Death in Retinitis Pigmentosa.

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Hexokinase-2-mediated aerobic glycolysis is integral to cerebellar neurogenesis and pathogenesis of medulloblastoma

http://www.wikidata.org/entity/Q37196742

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article científic

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bilimsel makale

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scientific article published on 23 January 2013

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vetenskaplig artikel

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videnskabelig artikel

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name

Hexokinase-2-mediated aerobic ...... athogenesis of medulloblastoma

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Hexokinase-2-mediated aerobic ...... thogenesis of medulloblastoma.

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Hexokinase-2-mediated aerobic ...... athogenesis of medulloblastoma

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Hexokinase-2-mediated aerobic ...... thogenesis of medulloblastoma.

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Hexokinase-2-mediated aerobic ...... athogenesis of medulloblastoma

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Hexokinase-2-mediated aerobic ...... thogenesis of medulloblastoma.

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Cancer & Metabolism

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Hexokinase-2-mediated aerobic ...... athogenesis of medulloblastoma

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Andrew J Crowther

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Andrey Tikunov

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Hong Yuan

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Idoia Garcia

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James Olson

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Jeffrey Macdonald

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Mohanish Deshmukh

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Ryan Annis

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Timothy R Gershon

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P2860

Catabolic efficiency of aerobic glycolysis: the Warburg effect revisited

Hexokinase II: cancer's double-edged sword acting as both facilitator and gatekeeper of malignancy when bound to mitochondria

Understanding the Warburg effect: the metabolic requirements of cell proliferation

Links between metabolism and cancer

Hexokinase-2 bound to mitochondria: cancer's stygian link to the "Warburg Effect" and a pivotal target for effective therapy

The AMP-activated protein kinase cascade--a unifying system for energy control

Medulloblastoma: developmental mechanisms out of control

Inhibition of early apoptotic events by Akt/PKB is dependent on the first committed step of glycolysis and mitochondrial hexokinase

Control of neuronal precursor proliferation in the cerebellum by Sonic Hedgehog

CIP2A increases self-renewal and is linked to Myc in neural progenitor cells

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10.1186/2049-3002-1-2

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24280485

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medulloblastoma

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3782751

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