Combined sensitization of mice to extracts of dust mite, ragweed, and Aspergillus species breaks through tolerance and establishes chronic features of asthma.
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Understanding asthma using animal modelsNeutralisation of interleukin-13 in mice prevents airway pathology caused by chronic exposure to house dust mite.Establishment of extracellular signal-regulated kinase 1/2 bistability and sustained activation through Sprouty 2 and its relevance for epithelial function.IL-33 and thymic stromal lymphopoietin mediate immune pathology in response to chronic airborne allergen exposureAnti-Asthma Simplified Herbal Medicine Intervention-induced long-lasting tolerance to allergen exposure in an asthma model is interferon-γ, but not transforming growth factor-β dependentAlveolar macrophages play a key role in cockroach-induced allergic inflammation via TNF-α pathway.Mitogen-activated protein kinase signalling and ERK1/2 bistability in asthma.Development of a novel severe triple allergen asthma model in mice which is resistant to dexamethasone and partially resistant to TLR7 and TLR9 agonist treatment.Mucosal exposure to cockroach extract induces allergic sensitization and allergic airway inflammation.The role of low-level lactate production in airway inflammation in asthmaPersistence of asthma requires multiple feedback circuits involving type 2 innate lymphoid cells and IL-33.ERK1 is important for Th2 differentiation and development of experimental asthma.Monitoring inflammation and airway remodeling by fluorescence molecular tomography in a chronic asthma model.The transcription factor PU.1 promotes alternative macrophage polarization and asthmatic airway inflammationFoxO1 regulates allergic asthmatic inflammation through regulating polarization of the macrophage inflammatory phenotype.Autotaxin production of lysophosphatidic acid mediates allergic asthmatic inflammation.Lyn mitigates mouse airway remodeling by downregulating the TGF-β3 isoform in house dust mite models.Fungal proteases and their pathophysiological effects.Aspergillus in chronic lung disease: Modeling what goes on in the airways.The effects of pregnancy on the exacerbation and development of maternal allergic respiratory disease.Dietary galacto-oligosaccharides prevent airway eosinophilia and hyperresponsiveness in a murine house dust mite-induced asthma model.Animal models of asthma.Experimental asthma persists in IL-33 receptor knockout mice because of the emergence of thymic stromal lymphopoietin-driven IL-9+ and IL-13+ type 2 innate lymphoid cell subpopulations.Relaxant effect of superimposed length oscillation on sensitized airway smooth muscle.Innate and adaptive immune responses to fungi in the airway
P2860
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P2860
Combined sensitization of mice to extracts of dust mite, ragweed, and Aspergillus species breaks through tolerance and establishes chronic features of asthma.
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on April 2009
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Combined sensitization of mice ...... es chronic features of asthma.
@en
Combined sensitization of mice ...... es chronic features of asthma.
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type
label
Combined sensitization of mice ...... es chronic features of asthma.
@en
Combined sensitization of mice ...... es chronic features of asthma.
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prefLabel
Combined sensitization of mice ...... es chronic features of asthma.
@en
Combined sensitization of mice ...... es chronic features of asthma.
@nl
P2093
P2860
P1476
Combined sensitization of mice ...... es chronic features of asthma.
@en
P2093
M Zunayet Karim
Magdalena M Gorska
Nicholas Goplen
Qiaoling Liang
Rafeul Alam
Sadee Rozario
P2860
P304
925-32.e11
P356
10.1016/J.JACI.2009.02.009
P407
P577
2009-04-01T00:00:00Z