Contributions of the individual hydrophobic clefts of the Escherichia coli beta sliding clamp to clamp loading, DNA replication and clamp recycling
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A Genetic Selection for dinB Mutants Reveals an Interaction between DNA Polymerase IV and the Replicative Polymerase That Is Required for Translesion SynthesisPolymerase exchange on single DNA molecules reveals processivity clamp control of translesion synthesis.Coordinating DNA polymerase traffic during high and low fidelity synthesis.A single hydrophobic cleft in the Escherichia coli processivity clamp is sufficient to support cell viability and DNA damage-induced mutagenesis in vivoEscherichia coli DNA polymerase IV (Pol IV), but not Pol II, dynamically switches with a stalled Pol III* replicaseIdentification of β Clamp-DNA Interaction Regions That Impair the Ability of E. coli to Tolerate Specific Classes of DNA Damage.The β2 clamp in the Mycobacterium tuberculosis DNA polymerase III αβ2ε replicase promotes polymerization and reduces exonuclease activity.Exchange between Escherichia coli polymerases II and III on a processivity clamp.A direct proofreader-clamp interaction stabilizes the Pol III replicase in the polymerization mode.A model for DNA polymerase switching involving a single cleft and the rim of the sliding clampArchitecture of the Pol III-clamp-exonuclease complex reveals key roles of the exonuclease subunit in processive DNA synthesis and repair.Mutations in the Bacillus subtilis beta clamp that separate its roles in DNA replication from mismatch repair.The Roles of UmuD in Regulating Mutagenesis.Escherichia coli processivity clamp β from DNA polymerase III is dynamic in solution.
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Contributions of the individual hydrophobic clefts of the Escherichia coli beta sliding clamp to clamp loading, DNA replication and clamp recycling
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article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 11 March 2009
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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Contributions of the individua ...... eplication and clamp recycling
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Contributions of the individua ...... plication and clamp recycling.
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Contributions of the individua ...... eplication and clamp recycling
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Contributions of the individua ...... plication and clamp recycling.
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prefLabel
Contributions of the individua ...... eplication and clamp recycling
@en
Contributions of the individua ...... plication and clamp recycling.
@nl
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Contributions of the individua ...... eplication and clamp recycling
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Jill M Duzen
Mark D Sutton
Sarah K Scouten Ponticelli
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10.1093/NAR/GKP128
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2009-03-11T00:00:00Z