Involvement of all-trans-retinal in acute light-induced retinopathy of mice. - Wikidata - awgldk - TriplyDB

Involvement of all-trans-retinal in acute light-induced retinopathy of mice.

Involvement of all-trans-retinal in acute light-induced retinopathy of mice.

http://www.wikidata.org/entity/Q37200892

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Pathogenesis of Zika Virus-Associated Embryopathy The Photobiology of Lutein and Zeaxanthin in the Eye Vitamin A Transport Mechanism of the Multitransmembrane Cell-Surface Receptor STRA6 Signal transducer and activator of transcription 3 (STAT3) signaling in retinal pigment epithelium cells Chemistry of the retinoid (visual) cycle Retinol dehydrogenase 13 protects the mouse retina from acute light damage Visual Cycle Modulation as an Approach toward Preservation of Retinal Integrity Phloroglucinol protects retinal pigment epithelium and photoreceptor against all-trans-retinal-induced toxicity and inhibits A2E formation Chemistry and biology of the initial steps in vision: the Friedenwald lecture.PBN (Phenyl-N-Tert-Butylnitrone)-Derivatives Are Effective in Slowing the Visual Cycle and Rhodopsin Regeneration and in Protecting the Retina from Light-Induced Damage Phospholipid meets all-trans-retinal: the making of RPE bisretinoids NinaB is essential for Drosophila vision but induces retinal degeneration in opsin-deficient photoreceptors.Phagocytosis of retinal rod and cone photoreceptors.Neuroprotective effect of bilberry extract in a murine model of photo-stressed retina Fundus autofluorescence and the bisretinoids of retina.All-trans-retinal induces Bax activation via DNA damage to mediate retinal cell apoptosis.Rational Tuning of Visual Cycle Modulator Pharmacodynamics Constituents of bile, bilirubin and TUDCA, protect against oxidative stress-induced retinal degeneration Fatty acid transport protein 1 regulates retinoid metabolism and photoreceptor development in mouse retina.Retinoids for treatment of retinal diseases Palmitoylation stabilizes unliganded rod opsin.Vitamin A dimers trigger the protracted death of retinal pigment epithelium cells Comparison of A2E cytotoxicity and phototoxicity with all-trans-retinal in human retinal pigment epithelial cells Expression of novel opsins and intrinsic light responses in the mammalian retinal ganglion cell line RGC-5. Presence of OPN5 in the rat retina The ATP-binding cassette transporter ABCA4: structural and functional properties and role in retinal disease.Retinal degeneration in animal models with a defective visual cycle.Fatty acid transport protein 4 (FATP4) prevents light-induced degeneration of cone and rod photoreceptors by inhibiting RPE65 isomerase.C20-D3-vitamin A slows lipofuscin accumulation and electrophysiological retinal degeneration in a mouse model of Stargardt disease.Noninvasive multiphoton fluorescence microscopy resolves retinol and retinal condensation products in mouse eyes.Transcriptional profile analysis of RPGRORF15 frameshift mutation identifies novel genes associated with retinal degeneration.Toll-like receptor 3 is required for development of retinopathy caused by impaired all-trans-retinal clearance in mice.Rod outer segment retinol formation is independent of Abca4, arrestin, rhodopsin kinase, and rhodopsin palmitylation Conformational selection and equilibrium governs the ability of retinals to bind opsin.Expansion of first-in-class drug candidates that sequester toxic all-trans-retinal and prevent light-induced retinal degeneration.Key enzymes of the retinoid (visual) cycle in vertebrate retina Prolonged prevention of retinal degeneration with retinylamine loaded nanoparticles.Posttranslational modifications of the photoreceptor-specific ABC transporter ABCA4 Membrane receptors and transporters involved in the function and transport of vitamin A and its derivatives.Protein misfolding and the pathogenesis of ABCA4-associated retinal degenerations.The susceptibility of the retina to photochemical damage from visible light.

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Involvement of all-trans-retinal in acute light-induced retinopathy of mice.

http://www.wikidata.org/entity/Q37200892

description

article científic

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article scientifique

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articolo scientifico

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artigo científico

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bilimsel makale

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scientific article published on 20 March 2009

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vedecký článok

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vetenskaplig artikel

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vědecký článek

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name

Involvement of all-trans-retinal in acute light-induced retinopathy of mice.

@en

Involvement of all-trans-retinal in acute light-induced retinopathy of mice.

@nl

type

label

Involvement of all-trans-retinal in acute light-induced retinopathy of mice.

@en

Involvement of all-trans-retinal in acute light-induced retinopathy of mice.

@nl

prefLabel

Involvement of all-trans-retinal in acute light-induced retinopathy of mice.

@en

Involvement of all-trans-retinal in acute light-induced retinopathy of mice.

@nl

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Journal of Biological Chemistry

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Involvement of all-trans-retinal in acute light-induced retinopathy of mice.

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Akiko Maeda

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Amar Desai

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Charles L Hoppel

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Marcin Golczak

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Shigemi Matsuyama

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Steven Chou

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Tadao Maeda

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P2860

Identification and characterization of all-trans-retinol dehydrogenase from photoreceptor outer segments, the visual cycle enzyme that reduces all-trans-retinal to all-trans-retinol

X-linked IAP is a direct inhibitor of cell-death proteases

A photoreceptor cell-specific ATP-binding transporter gene (ABCR) is mutated in recessive Stargardt macular dystrophy

Role of photoreceptor-specific retinol dehydrogenase in the retinoid cycle in vivo.

Opsin activation of transduction in the rods of dark-reared Rpe65 knockout mice

Retinopathy in mice induced by disrupted all-trans-retinal clearance

Pharmacological and rAAV gene therapy rescue of visual functions in a blind mouse model of Leber congenital amaurosis.

Insights into the function of Rim protein in photoreceptors and etiology of Stargardt's disease from the phenotype in abcr knockout mice

Mutation of the Stargardt disease gene (ABCR) in age-related macular degeneration

A critical role of CaBP4 in the cone synapse.

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15173-15183

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scholarly article

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10.1074/JBC.M900322200

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22

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284

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Krzysztof Palczewski

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2009-03-20T00:00:00Z

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19304658

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2685698

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