Hexavalent chromium is carcinogenic to F344/N rats and B6C3F1 mice after chronic oral exposure.
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Hexavalent chromium exposure and control in welding tasksAssessment of Cr(VI)-induced cytotoxicity and genotoxicity using high content analysisAssessment of the mode of action underlying development of rodent small intestinal tumors following oral exposure to hexavalent chromium and relevance to humansBasic mechanics of DNA methylation and the unique landscape of the DNA methylome in metal-induced carcinogenesisApplication of the U.S. EPA mode of action Framework for purposes of guiding future research: a case study involving the oral carcinogenicity of hexavalent chromiumCoQ10 Deficiency May Indicate Mitochondrial Dysfunction in Cr(VI) Toxicity.An evaluation of the protective role of vitamin C in reactive oxygen species-induced hepatotoxicity due to hexavalent chromium in vitro and in vivo.Chromium and genomic stabilityExposure to hexavalent chromium resulted in significantly higher tissue chromium burden compared with trivalent chromium following similar oral doses to male F344/N rats and female B6C3F1 mice.Spatiotemporal trends in oral cancer mortality and potential risks associated with heavy metal content in Taiwan soil.Evaluating the Impact of the U.S. National Toxicology Program: A Case Study on Hexavalent ChromiumSynchrotron-based imaging of chromium and γ-H2AX immunostaining in the duodenum following repeated exposure to Cr(VI) in drinking water.A chronic oral reference dose for hexavalent chromium-induced intestinal cancer.Hexavalent chromium in house dust--a comparison between an area with historic contamination from chromate production and background locations.Oral ingestion of hexavalent chromium through drinking water and cancer mortality in an industrial area of Greece--an ecological study.Investigation of the mode of action underlying the tumorigenic response induced in B6C3F1 mice exposed orally to hexavalent chromium.Comparison of the effects of hexavalent chromium in the alimentary canal of F344 rats and B6C3F1 mice following exposure in drinking water: implications for carcinogenic modes of action.Oral Chromium Exposure and Toxicity.Literature review of the role of hydroxyl radicals in chemically-induced mutagenicity and carcinogenicity for the risk assessment of a disinfection system utilizing photolysis of hydrogen peroxideAdsorptive Removal of Toxic Chromium from Waste-Water Using Wheat Straw and Eupatorium adenophorum.Reevaluation and Classification of Duodenal Lesions in B6C3F1 Mice and F344 Rats from 4 Studies of Hexavalent Chromium in Drinking Water.14-Day Toxicity Studies of Tetravalent and Pentavalent Vanadium Compounds in Harlan Sprague Dawley Rats and B6C3F1/N Mice via Drinking Water Exposure.Transcriptomic responses in the oral cavity of F344 rats and B6C3F1 mice following exposure to Cr(VI): Implications for risk assessment.Blood nickel and chromium levels in association with smoking and occupational exposure among head and neck cancer patients in Tunisia.A critical exploration of blood and environmental chromium concentration among oral cancer patients in an oral cancer prevalent area of Taiwan.Assessment of the mutagenic potential of Cr(VI) in the oral mucosa of Big Blue® transgenic F344 rats.Cr(VI) speciation in foods by HPLC-ICP-MS: investigation of Cr(VI)/food interactions by size exclusion and Cr(VI) determination and stability by ion-exchange on-line separations.Carcinogenicity of chromium and chemoprevention: a brief updateMitochondrial Biogenesis in Response to Chromium (VI) Toxicity in Human Liver Cells.Validation and application of a method for the determination of total chromium in rat tissues by inductively coupled plasma mass spectrometry.Elevated tissue Cr levels, increased plasma oxidative markers, and global hypomethylation of blood DNA in male Sprague-Dawley rats exposed to potassium dichromate in drinking water.Cr(VI) induces lipid peroxidation, protein oxidation and alters the activities of antioxidant enzymes in human erythrocytes.Effects of chronic chromium(vi) exposure on blood element homeostasis: an epidemiological study.Comparative studies of tri- and hexavalent chromium cytotoxicity and their effects on oxidative state of Saccharomyces cerevisiae cells.Assessment of immunotoxicity in female Fischer 344/N and Sprague Dawley rats and female B6C3F1 mice exposed to hexavalent chromium via the drinking water.Comparison of Toxicity and Recovery in the Duodenum of B6C3F1 Mice Following Treatment with Intestinal Carcinogens Captan, Folpet, and Hexavalent Chromium.A robust method for assessing chemically induced mutagenic effects in the oral cavity of transgenic Big Blue® rats.A Multidisciplinary Assessment of River Surface Water Quality in Areas Heavily Influenced by Human Activities.Scientific Opinion on the risks to public health related to the presence of chromium in food and drinking waterUpregulation of histone-lysine methyltransferases plays a causal role in hexavalent chromium-induced cancer stem cell-like property and cell transformation.
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Hexavalent chromium is carcinogenic to F344/N rats and B6C3F1 mice after chronic oral exposure.
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 31 December 2008
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Hexavalent chromium is carcino ...... e after chronic oral exposure.
@en
Hexavalent chromium is carcino ...... e after chronic oral exposure.
@nl
type
label
Hexavalent chromium is carcino ...... e after chronic oral exposure.
@en
Hexavalent chromium is carcino ...... e after chronic oral exposure.
@nl
prefLabel
Hexavalent chromium is carcino ...... e after chronic oral exposure.
@en
Hexavalent chromium is carcino ...... e after chronic oral exposure.
@nl
P2093
P2860
P356
P1476
Hexavalent chromium is carcino ...... e after chronic oral exposure.
@en
P2093
Bradley J Collins
David E Malarkey
Grace E Kissling
Gregory S Travlos
Kamal M Abdo
Kristine L Witt
Matthew D Stout
Michelle J Hooth
Ronald A Herbert
Ronald L Melnick
P2860
P304
P356
10.1289/EHP.0800208
P577
2008-12-31T00:00:00Z