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mSYD1A, a mammalian synapse-defective-1 protein, regulates synaptogenic signaling and vesicle dockingSuperresolution imaging of chemical synapses in the brain.To build a synapse: signaling pathways in neuromuscular junction assemblySynCAM 1 adhesion dynamically regulates synapse number and impacts plasticity and learning.The proteasome controls presynaptic differentiation through modulation of an on-site pool of polyubiquitinated conjugatesN-Glycosylation at the SynCAM (Synaptic Cell Adhesion Molecule) Immunoglobulin Interface Modulates Synaptic AdhesionA Cdc20-APC ubiquitin signaling pathway regulates presynaptic differentiationDifferential expression of liprin-α family proteins in the brain suggests functional diversificationRPM-1 uses both ubiquitin ligase and phosphatase-based mechanisms to regulate DLK-1 during neuronal developmentAPP Is a Context-Sensitive Regulator of the Hippocampal Presynaptic Active ZoneBassoon and Piccolo maintain synapse integrity by regulating protein ubiquitination and degradationMolecular in situ topology of Aczonin/Piccolo and associated proteins at the mammalian neurotransmitter release siteActivity-dependent adaptations in inhibitory axonsVisual deprivation increases accumulation of dense core vesicles in developing optic tectal synapses in Xenopus laevisSynCAM 1 participates in axo-dendritic contact assembly and shapes neuronal growth cones.Acute knockdown of AMPA receptors reveals a trans-synaptic signal for presynaptic maturation.An Arf-like small G protein, ARL-8, promotes the axonal transport of presynaptic cargoes by suppressing vesicle aggregationThe Bruchpilot cytomatrix determines the size of the readily releasable pool of synaptic vesicles.Local caspase activation interacts with Slit-Robo signaling to restrict axonal arborization.The DLK-1 kinase promotes mRNA stability and local translation in C. elegans synapses and axon regenerationA modifier screen in the Drosophila eye reveals that aPKC interacts with Glued during central synapse formationMotor neuron synapse and axon defects in a C. elegans alpha-tubulin mutant.Functions of axon guidance molecules in synapse formation.A Syd-1 homologue regulates pre- and postsynaptic maturation in Drosophila.Drosophila Syd-1, liprin-α, and protein phosphatase 2A B' subunit Wrd function in a linear pathway to prevent ectopic accumulation of synaptic materials in distal axons.Neuroligin-deficient mutants of C. elegans have sensory processing deficits and are hypersensitive to oxidative stress and mercury toxicity.The presynaptic dense projection of the Caenorhabditis elegans cholinergic neuromuscular junction localizes synaptic vesicles at the active zone through SYD-2/liprin and UNC-10/RIM-dependent interactionsDifferential regulation of polarized synaptic vesicle trafficking and synapse stability in neural circuit rewiring in Caenorhabditis elegansA ubiquitin E2 variant protein acts in axon termination and synaptogenesis in Caenorhabditis elegansSystematic analyses of rpm-1 suppressors reveal roles for ESS-2 in mRNA splicing in Caenorhabditis elegans.Developmental up-regulation of vesicular glutamate transporter-1 promotes neocortical presynaptic terminal development.2mit, an intronic gene of Drosophila melanogaster timeless2, is involved in behavioral plasticity.Orchestrating the synaptic network by tyrosine phosphorylation signallingLateral assembly of the immunoglobulin protein SynCAM 1 controls its adhesive function and instructs synapse formation.Advances in imaging ultrastructure yield new insights into presynaptic biologyDistinct sets of FGF receptors sculpt excitatory and inhibitory synaptogenesis.Facilitation of neocortical presynaptic terminal development by NMDA receptor activation.Afadin, a Ras/Rap effector that controls cadherin function, promotes spine and excitatory synapse density in the hippocampusNetrin instructs synaptic vesicle clustering through Rac GTPase, MIG-10, and the actin cytoskeleton.Presynaptic active zones in invertebrates and vertebrates.
P2860
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P2860
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on January 2008
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Molecular mechanisms of presynaptic differentiation.
@en
Molecular mechanisms of presynaptic differentiation.
@nl
type
label
Molecular mechanisms of presynaptic differentiation.
@en
Molecular mechanisms of presynaptic differentiation.
@nl
prefLabel
Molecular mechanisms of presynaptic differentiation.
@en
Molecular mechanisms of presynaptic differentiation.
@nl
P1476
Molecular mechanisms of presynaptic differentiation.
@en
P2093
Craig C Garner
P304
P356
10.1146/ANNUREV.CELLBIO.23.090506.123417
P50
P577
2008-01-01T00:00:00Z