Signaling through fibroblast growth factor receptor 2b plays a key role in the development of the exocrine pancreas.
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Receptor specificity of the fibroblast growth factor family. The complete mammalian FGF familyFibroblast Growth Factor Signaling in Metabolic RegulationGeneration of β cells from human pluripotent stem cells: are we there yet?Recent developments in β-cell differentiation of pluripotent stem cells induced by small and large moleculesFunctional roles of fibroblast growth factor receptors (FGFRs) signaling in human cancersDirected pancreatic acinar differentiation of mouse embryonic stem cells via embryonic signalling molecules and exocrine transcription factorsWnt/beta-catenin signaling is required for development of the exocrine pancreasEffects of mutations in the insulin-like growth factor signaling system on embryonic pancreas development and beta-cell compensation to insulin resistanceHuman pancreatic precursor cells secrete FGF2 to stimulate clustering into hormone-expressing islet-like cell aggregatesINS(GFP/w) human embryonic stem cells facilitate isolation of in vitro derived insulin-producing cellsRetinoic acid promotes the generation of pancreatic endocrine progenitor cells and their further differentiation into beta-cellsOxygen tension regulates pancreatic beta-cell differentiation through hypoxia-inducible factor 1alpha.Role of nutrients and mTOR signaling in the regulation of pancreatic progenitors development.Differentiation of mouse embryonic stem cells into endoderm without embryoid body formationTherapeutic effect of nanogel-based delivery of soluble FGFR2 with S252W mutation on craniosynostosis.Role for FGFR2IIIb-mediated signals in controlling pancreatic endocrine progenitor cell proliferation.Proliferative signaling initiated in ACTH receptors.Generation of glucose-responsive functional islets with a three-dimensional structure from mouse fetal pancreatic cells and iPS cells in vitroA system for ex vivo culturing of embryonic pancreasHistorical perspective: beginnings of the beta-cell: current perspectives in beta-cell developmentDevelopment and diseases of the pancreas.Obestatin enhances in vitro generation of pancreatic islets through regulation of developmental pathways.Alternative sources of beta cells for cell therapy of diabetes.New insights into endocrine pancreatic development: the role of environmental factors.Insulin-like growth factor and fibroblast growth factor expression profiles in growth-restricted fetal sheep pancreas.Fibroblast growth factor receptor-1 signaling in pancreatic islet beta-cells is modulated by the extracellular matrix.Analysis of mPygo2 mutant mice suggests a requirement for mesenchymal Wnt signaling in pancreatic growth and differentiation.Development of the human pancreas from foregut to endocrine commitment.On the origin of the beta cell.Presenilins, Notch dose control the fate of pancreatic endocrine progenitors during a narrow developmental window.The hexosamine biosynthesis pathway is essential for pancreatic beta cell development.Pancreas cell fate.Impaired pancreatic growth, beta cell mass, and beta cell function in E2F1 (-/- )miceExocrine ontogenies: on the development of pancreatic acinar, ductal and centroacinar cellsUnderstanding pancreas development for β-cell repair and replacement therapies.Identification of embryonic pancreatic genes using Xenopus DNA microarrays.Conditional control of the differentiation competence of pancreatic endocrine and ductal cells by Fgf10.Maintenance of mouse, rat, and pig pancreatic islet functions by coculture with human islet-derived fibroblasts.Effect of epiregulin on pancreatic beta cell growth and insulin secretion.Associations of FGF-3 and FGF-10 with signaling networks regulating tooth morphogenesis.
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Signaling through fibroblast growth factor receptor 2b plays a key role in the development of the exocrine pancreas.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on May 1999
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Signaling through fibroblast g ...... ment of the exocrine pancreas.
@en
Signaling through fibroblast g ...... ment of the exocrine pancreas.
@nl
type
label
Signaling through fibroblast g ...... ment of the exocrine pancreas.
@en
Signaling through fibroblast g ...... ment of the exocrine pancreas.
@nl
prefLabel
Signaling through fibroblast g ...... ment of the exocrine pancreas.
@en
Signaling through fibroblast g ...... ment of the exocrine pancreas.
@nl
P2093
P2860
P356
P1476
Signaling through fibroblast g ...... pment of the exocrine pancreas
@en
P2093
P2860
P304
P356
10.1073/PNAS.96.11.6267
P407
P577
1999-05-01T00:00:00Z