Noninvasive detection of lentiviral-mediated choline kinase targeting in a human breast cancer xenograft - Wikidata - awgldk - TriplyDB

Noninvasive detection of lentiviral-mediated choline kinase targeting in a human breast cancer xenograft

Noninvasive detection of lentiviral-mediated choline kinase targeting in a human breast cancer xenograft

http://www.wikidata.org/entity/Q37204053

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Differential role of human choline kinase alpha and beta enzymes in lipid metabolism: implications in cancer onset and treatment Choline metabolism-based molecular diagnosis of cancer: an update Human Choline Kinase-α Promotes Hepatitis C Virus RNA Replication through Modulation of Membranous Viral Replication Complex Formation Key Players in Choline Metabolic Reprograming in Triple-Negative Breast Cancer Choline kinase and its function Highly specific antibodies for co-detection of human choline kinase α1 and α2 isoforms Functional interactions between Choline kinase α, epidermal growth factor receptor and c-Src in breast cancer cell proliferation Silencing of the glycerophosphocholine phosphodiesterase GDPD5 alters the phospholipid metabolite profile in a breast cancer model in vivo as monitored by (31) P MRS.Effect of Pantethine on Ovarian Tumor Progression and Choline Metabolism.In vivo imaging of RNA interference.Activation of phosphatidylcholine cycle enzymes in human epithelial ovarian cancer cells.PSMA-targeted theranostic nanoplex for prostate cancer therapy.Molecular Effects of Doxorubicin on Choline Metabolism in Breast Cancer.Magnetic resonance spectroscopy in metabolic and molecular imaging and diagnosis of cancer Applications of molecular MRI and optical imaging in cancer.Glycerophosphodiester phosphodiesterase domain containing 5 (GDPD5) expression correlates with malignant choline phospholipid metabolite profiles in human breast cancer Image-guided breast tumor therapy using a small interfering RNA nanodrug Hypoxia regulates CD44 and its variant isoforms through HIF-1α in triple negative breast cancer.The FGF-1-specific single-chain antibody scFv1C9 effectively inhibits breast cancer tumour growth and metastasis.Choline metabolism in malignant transformation.Metabolic tumor imaging using magnetic resonance spectroscopy.Global metabolic profile identifies choline kinase alpha as a key regulator of glutathione-dependent antioxidant cell defense in ovarian carcinoma Choline kinase alpha-Putting the ChoK-hold on tumor metabolism.Characterization of choline kinase in human endothelial cells.The novel choline kinase inhibitor ICL-CCIC-0019 reprograms cellular metabolism and inhibits cancer cell growth.Choline kinase-alpha by regulating cell aggressiveness and drug sensitivity is a potential druggable target for ovarian cancer.Overexpression of CHKA contributes to tumor progression and metastasis and predicts poor prognosis in colorectal carcinoma.Dovitinib synergizes with oxaliplatin in suppressing cell proliferation and inducing apoptosis in colorectal cancer cells regardless of RAS-RAF mutation status.MR evaluation of response to targeted treatment in cancer cells.MRS and MRSI guidance in molecular medicine: targeting and monitoring of choline and glucose metabolism in cancer.Targeting choline phospholipid metabolism: GDPD5 and GDPD6 silencing decrease breast cancer cell proliferation, migration, and invasion.Choline kinase-α protein and phosphatidylcholine but not phosphocholine are required for breast cancer cell survival.Metabolic imaging of pancreatic ductal adenocarcinoma detects altered choline metabolism.New more polar symmetrical bipyridinic compounds: new strategy for the inhibition of choline kinase α1.The Tumor Microenvironment Modulates Choline and Lipid Metabolism.Targeting Phospholipid Metabolism in Cancer.Metabolic signatures imaged in cancer-induced cachexia.In vivo pH imaging with (99m)Tc-pHLIP Magnetic Resonance Spectroscopy Studies of Mouse Models of Cancer.Choline Kinase Alpha Inhibition by EB-3D Triggers Cellular Senescence, Reduces Tumor Growth and Metastatic Dissemination in Breast Cancer

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Noninvasive detection of lentiviral-mediated choline kinase targeting in a human breast cancer xenograft

http://www.wikidata.org/entity/Q37204053

description

article científic

@ca

article scientifique

@fr

articolo scientifico

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artigo científico

@pt

bilimsel makale

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scientific article published on 31 March 2009

@en

vedecký článok

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vetenskaplig artikel

@sv

videnskabelig artikel

@da

vědecký článek

@cs

name

Noninvasive detection of lenti ...... human breast cancer xenograft

@en

Noninvasive detection of lenti ...... human breast cancer xenograft.

@nl

type

label

Noninvasive detection of lenti ...... human breast cancer xenograft

@en

Noninvasive detection of lenti ...... human breast cancer xenograft.

@nl

prefLabel

Noninvasive detection of lenti ...... human breast cancer xenograft

@en

Noninvasive detection of lenti ...... human breast cancer xenograft.

@nl

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0008-5472.CAN-08-4120

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Cancer Research

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Noninvasive detection of lenti ...... human breast cancer xenograft

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Balaji Krishnamachary

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Flonne Wildes

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Kristine Glunde

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Noriko Mori

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Tomoyo Takagi

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Venu Raman

http://www.w3.org/2001/XMLSchema#string

Zaver M Bhujwalla

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P2860

Gene therapy in clinical medicine

Choline kinase down-regulation increases the effect of 5-fluorouracil in breast cancer cells

In vivo gene delivery and stable transduction of nondividing cells by a lentiviral vector

Real-time changes in 1H and 31P NMR spectra of malignant human mammary epithelial cells during treatment with the anti-inflammatory agent indomethacin.

Lentiviral vectors: excellent tools for experimental gene transfer and promising candidates for gene therapy.

Increased choline kinase activity in human breast carcinomas: clinical evidence for a potential novel antitumor strategy.

Choline phospholipid metabolism: a target in cancer cells?

Delivery of viral vectors to tumor cells: extracellular transport, systemic distribution, and strategies for improvement.

Gene therapy for transplantation with viral vectors--how much of the promise has been realised?

Efficient transfer, integration, and sustained long-term expression of the transgene in adult rat brains injected with a lentiviral vector.

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3464-3471

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10.1158/0008-5472.CAN-08-4120

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8

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19336572

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