Turning tumor-promoting copper into an anti-cancer weapon via high-throughput chemistry
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Downregulation of oncogenic RAS and c-Myc expression in MOLT-4 leukaemia cells by a salicylaldehyde semicarbazone copper(II) complexSite-specific radical formation in DNA induced by Cu(II)-H₂O₂ oxidizing system, using ESR, immuno-spin trapping, LC-MS, and MS/MSDetection and imaging of the free radical DNA in cells--site-specific radical formation induced by Fenton chemistry and its repair in cellular DNA as seen by electron spin resonance, immuno-spin trapping and confocal microscopy.Cancer cell-selective killing polymer/copper combination.Potential usage of proteasome inhibitor bortezomib (Velcade, PS-341) in the treatment of metastatic melanoma: basic and clinical aspectsCopper (II) complexes of bidentate ligands exhibit potent anti-cancer activity regardless of platinum sensitivity status.Selective formation of discrete versus polymeric copper organophosphates: DNA cleavage and cytotoxic activity.Disulfiram combined with copper inhibits metastasis and epithelial-mesenchymal transition in hepatocellular carcinoma through the NF-κB and TGF-β pathways.
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Q28821489-62D0F9C0-1576-4085-BA22-CECF7FE42B6EQ34999488-C47FACAB-99FF-47E4-9064-A2C09AA31A74Q36061874-AB7781AA-1A3B-4FF0-B710-344A2B8300EEQ36372931-80A82405-98A4-4744-AA81-BC564BE268DEQ37948056-AFD2A0EB-A351-40C1-80A5-E091330FF44FQ38667138-5CCF9AF4-1599-4AE1-8538-EE4E3C9CD8C0Q42693147-EBD947EB-901B-4FCD-8044-7DA359E13937Q47096948-EE78EB65-74F4-4917-81E4-DCD154A06EC4
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Turning tumor-promoting copper into an anti-cancer weapon via high-throughput chemistry
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article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on January 2010
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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Turning tumor-promoting copper into an anti-cancer weapon via high-throughput chemistry
@en
Turning tumor-promoting copper into an anti-cancer weapon via high-throughput chemistry.
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type
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Turning tumor-promoting copper into an anti-cancer weapon via high-throughput chemistry
@en
Turning tumor-promoting copper into an anti-cancer weapon via high-throughput chemistry.
@nl
prefLabel
Turning tumor-promoting copper into an anti-cancer weapon via high-throughput chemistry
@en
Turning tumor-promoting copper into an anti-cancer weapon via high-throughput chemistry.
@nl
P2093
P2860
P1476
Turning tumor-promoting copper into an anti-cancer weapon via high-throughput chemistry
@en
P2093
P2860
P304
P356
10.2174/092986710791859315
P577
2010-01-01T00:00:00Z