A simplified PBPK modeling approach for prediction of pharmacokinetics of four primarily renally excreted and CYP3A metabolized compounds during pregnancy
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Physiologically Based Pharmacokinetic (PBPK) Modeling and Simulation Approaches: A Systematic Review of Published Models, Applications, and Model VerificationDevelopment of a Whole-Body Physiologically Based Pharmacokinetic Approach to Assess the Pharmacokinetics of Drugs in Elderly IndividualsDevelopment of Physiologically Based Pharmacokinetic/Pharmacodynamic Model for Indomethacin Disposition in PregnancyPhysiologically-based pharmacokinetic modeling of renally excreted antiretroviral drugs in pregnant women.Maternal use of drug substrates of placental transporters and the effect of transporter-mediated drug interactions on the risk of congenital anomalies.Population Pharmacokinetics of Rifampin in Pregnant Women with Tuberculosis and HIV Coinfection in Soweto, South Africa.The Promises of Quantitative Proteomics in Precision MedicinePhysiologically based pharmacokinetic models of small molecules and therapeutic antibodies: a mini-review on fundamental concepts and applications.Physiologically Based Pharmacokinetic Modelling and Prediction of Metformin Pharmacokinetics in Renal/Hepatic-Impaired Young Adults and Elderly Populations.Application of physiologically based pharmacokinetic modeling to predict drug disposition in pregnant populations.Physiologically Based Pharmacokinetic Modeling of Renally Cleared Drugs in Pregnant Women.Development of a Physiologically Based Pharmacokinetic Modelling Approach to Predict the Pharmacokinetics of Vancomycin in Critically Ill Septic Patients.Drug Dosing in Pregnant Women: Challenges and Opportunities in Using Physiologically Based Pharmacokinetic Modeling and Simulations.Inclusion of pregnant and breastfeeding women in research - efforts and initiatives.A Physiologically Based Pharmacokinetic Model for Pregnant Women to Predict the Pharmacokinetics of Drugs Metabolized Via Several Enzymatic Pathways.A Physiologically-Based Pharmacokinetic Model to Predict Human Fetal Exposure for a Drug Metabolized by Several CYP450 Pathways.Physiologically Based Pharmacokinetic Prediction of Linezolid and Emtricitabine in Neonates and Infants.
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P2860
A simplified PBPK modeling approach for prediction of pharmacokinetics of four primarily renally excreted and CYP3A metabolized compounds during pregnancy
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
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scientific article published on 09 July 2013
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
A simplified PBPK modeling app ...... zed compounds during pregnancy
@en
A simplified PBPK modeling app ...... ed compounds during pregnancy.
@nl
type
label
A simplified PBPK modeling app ...... zed compounds during pregnancy
@en
A simplified PBPK modeling app ...... ed compounds during pregnancy.
@nl
prefLabel
A simplified PBPK modeling app ...... zed compounds during pregnancy
@en
A simplified PBPK modeling app ...... ed compounds during pregnancy.
@nl
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P2860
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A simplified PBPK modeling app ...... zed compounds during pregnancy
@en
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Binfeng Xia
Charvi Nanavati
Tycho Heimbach
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P2888
P304
P356
10.1208/S12248-013-9505-3
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P577
2013-07-09T00:00:00Z
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P6179
1000937478