Elevated insulin secretion from liver X receptor-activated pancreatic beta-cells involves increased de novo lipid synthesis and triacylglyceride turnover
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Cold Exposure Improves the Anti-diabetic Effect of T0901317 in Streptozotocin-Induced Diabetic Mice.Identification of a mammalian glycerol-3-phosphate phosphatase: Role in metabolism and signaling in pancreatic β-cells and hepatocytesNuclear receptors as drug targets for metabolic disease.Liver X receptor agonists augment human islet function through activation of anaplerotic pathways and glycerolipid/free fatty acid cycling.Susceptibility of pancreatic beta cells to fatty acids is regulated by LXR/PPARalpha-dependent stearoyl-coenzyme A desaturase.Coordinated Actions of FXR and LXR in Metabolism: From Pathogenesis to Pharmacological Targets for Type 2 DiabetesRole of fatty acid elongases in determination of de novo synthesized monounsaturated fatty acid speciesPadina arborescens extract protects high glucose-induced apoptosis in pancreatic β cells by reducing oxidative stress.Genome-wide analysis of SREBP1 activity around the clock reveals its combined dependency on nutrient and circadian signalsInhibition of SCD1 impairs palmitate-derived autophagy at the step of autophagosome-lysosome fusion in pancreatic β-cells.Phloroglucinol Protects INS-1 Pancreatic β-cells Against Glucotoxicity-Induced Apoptosis.Mechanisms of β-cell functional adaptation to changes in workloadAberrant activation of liver X receptors impairs pancreatic beta cell function through upregulation of sterol regulatory element-binding protein 1c in mouse islets and rodent cell lines.Modulation of palmitate-induced endoplasmic reticulum stress and apoptosis in pancreatic β-cells by stearoyl-CoA desaturase and Elovl6.
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Elevated insulin secretion from liver X receptor-activated pancreatic beta-cells involves increased de novo lipid synthesis and triacylglyceride turnover
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article científic
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article scientifique
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articolo scientifico
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artigo científico
@pt
bilimsel makale
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scientific article published on 19 February 2009
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Elevated insulin secretion fro ...... and triacylglyceride turnover
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Elevated insulin secretion fro ...... and triacylglyceride turnover.
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Elevated insulin secretion fro ...... and triacylglyceride turnover
@en
Elevated insulin secretion fro ...... and triacylglyceride turnover.
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Elevated insulin secretion fro ...... and triacylglyceride turnover
@en
Elevated insulin secretion fro ...... and triacylglyceride turnover.
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P2093
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P356
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Elevated insulin secretion fro ...... and triacylglyceride turnover
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Christopher D Green
Donald B Jump
L Karl Olson
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P304
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10.1210/EN.2008-1039
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P577
2009-02-19T00:00:00Z