Highlights at the gate of tryptophan catabolism: a review on the mechanisms of activation and regulation of indoleamine 2,3-dioxygenase (IDO), a novel target in cancer disease.
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Kynurenines in CNS disease: regulation by inflammatory cytokinesResearch progress of indoleamine 2,3-dioxygenase inhibitorsThe role of placental tryptophan catabolismImmunomodulatory effects of bone marrow-derived mesenchymal stem cells on pro-inflammatory cytokine-stimulated human corneal epithelial cells.Identification of a variable number of tandem repeats polymorphism and characterization of LEF-1 response elements in the promoter of the IDO1 geneThe mechanism of formation of N-formylkynurenine by heme dioxygenases.Inhibitors of indoleamine 2,3-dioxygenase: a review of novel patented lead compounds.Expression of tryptophan 2,3-dioxygenase and production of kynurenine pathway metabolites in triple transgenic mice and human Alzheimer's disease brainMolecular alterations in glioblastoma: potential targets for immunotherapy.Indoleamine 2,3 Dioxygenase (IDO) Expression and Activity in Relapsing-Remitting Multiple Sclerosis.Ligand migration in human indoleamine-2,3 dioxygenase.Glutamine and leucine provide enhanced protective immunity against mucosal infection with herpes simplex virus type 1.Determination of l-tryptophan and l-kynurenine in Human Serum by using LC-MS after Derivatization with (R)-DBD-PyNCS.Indoleamine 2,3-dioxygenase inhibitors: a patent review (2008 - 2012).Indoleamine 2,3-dioxygenase 2 (IDO2) and the kynurenine pathway: characteristics and potential roles in health and disease.Binding properties of different categories of IDO1 inhibitors: a microscale thermophoresis study.The Janus-faced nature of IDO1 in infectious diseases: challenges and therapeutic opportunities.Identifying factors contributing to slow growth in pigs.Docking Studies and Molecular Dynamic Simulations Reveal Different Features of IDO1 Structure.The mechanism of substrate inhibition in human indoleamine 2,3-dioxygenaseP53 prevent tumor invasion and metastasis by down-regulating IDO in lung cancer.N (1)-Fluoroalkyltryptophan Analogues: Synthesis and in vitro Study as Potential Substrates for Indoleamine 2,3-Dioxygenase.Objective measurement and clinical significance of IDO1 protein in hormone receptor-positive breast cancer.Enantiomeric Separation of Monosubstituted Tryptophan Derivatives and Metabolites by HPLC with a Cinchona Alkaloid-Based Zwitterionic Chiral Stationary Phase and Its Application to the Evaluation of the Optical Purity of Synthesized 6-Chloro-l-TryptMetabolite target analysis of human urine combined with pattern recognition techniques for the study of symptomatic gout.Vitamin B6 prevents cognitive impairment in experimental pneumococcal meningitis.A Multifaceted Role of Tryptophan Metabolism and Indoleamine 2,3-Dioxygenase Activity in Aspergillus fumigatus-Host Interactions.Regulating the balance between the kynurenine and serotonin pathways of tryptophan metabolism.Discovery of Novel Indoleamine 2,3-Dioxygenase 1 (IDO1) and Histone Deacetylase (HDAC) Dual Inhibitors.Benzofuranquinones as inhibitors of indoleamine 2,3-dioxygenase (IDO). Synthesis and biological evaluation.Inflammatory cytokines and cellular metabolites as synovial fluid biomarkers of posttraumatic ankle arthritis.
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P2860
Highlights at the gate of tryptophan catabolism: a review on the mechanisms of activation and regulation of indoleamine 2,3-dioxygenase (IDO), a novel target in cancer disease.
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article científic
@ca
article scientifique
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articolo scientifico
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artigo científico
@pt
bilimsel makale
@tr
scientific article published on 09 July 2008
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
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vědecký článek
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name
Highlights at the gate of tryp ...... ovel target in cancer disease.
@en
Highlights at the gate of tryp ...... ovel target in cancer disease.
@nl
type
label
Highlights at the gate of tryp ...... ovel target in cancer disease.
@en
Highlights at the gate of tryp ...... ovel target in cancer disease.
@nl
prefLabel
Highlights at the gate of tryp ...... ovel target in cancer disease.
@en
Highlights at the gate of tryp ...... ovel target in cancer disease.
@nl
P2093
P1433
P1476
Highlights at the gate of tryp ...... ovel target in cancer disease.
@en
P2093
Antonio Macchiarulo
Emidio Camaioni
Roberto Nuti
Roberto Pellicciari
P2860
P2888
P304
P356
10.1007/S00726-008-0137-3
P577
2008-07-09T00:00:00Z