Chlamydia trachomatis native major outer membrane protein induces partial protection in nonhuman primates: implication for a trachoma transmission-blocking vaccine.
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Will the SAFE strategy be sufficient to eliminate trachoma by 2020? Puzzlements and possible solutionsChlamydial polymorphic membrane proteins: regulation, function and potential vaccine candidatesStudy of the prevalence and association of ocular chlamydial conjunctivitis in women with genital infection by Chlamydia trachomatis, Mycoplasma genitalium and Candida albicans attending outpatient clinicIncreased immunoaccessibility of MOMP epitopes in a vaccine formulated with amphipols may account for the very robust protection elicited against a vaginal challenge with Chlamydia muridarum.Immunization with the attenuated plasmidless Chlamydia trachomatis L2(25667R) strain provides partial protection in a murine model of female genitourinary tract infectionAdaptive evolution of the Chlamydia trachomatis dominant antigen reveals distinct evolutionary scenarios for B- and T-cell epitopes: worldwide survey.Chlamydia muridarum T-cell antigens formulated with the adjuvant DDA/TDB induce immunity against infection that correlates with a high frequency of gamma interferon (IFN-gamma)/tumor necrosis factor alpha and IFN-gamma/interleukin-17 double-positiveWhole genome identification of C. trachomatis immunodominant antigens after genital tract infections and effect of antibiotic treatment of pigtailed macaques.Chlamydia trachomatis control requires a vaccine.Evaluation of a multisubunit recombinant polymorphic membrane protein and major outer membrane protein T cell vaccine against Chlamydia muridarum genital infection in three strains of mice.CD4+ T cells and antibody are required for optimal major outer membrane protein vaccine-induced immunity to Chlamydia muridarum genital infection.Enhancement of the protective efficacy of a Chlamydia trachomatis recombinant vaccine by combining systemic and mucosal routes for immunization.Identification of immunodominant antigens by probing a whole Chlamydia trachomatis open reading frame proteome microarray using sera from immunized mice.Vaccination against Chlamydia genital infection utilizing the murine C. muridarum model.Antibody signature of spontaneous clearance of Chlamydia trachomatis ocular infection and partial resistance against re-challenge in a nonhuman primate trachoma model.Immunogenicity of a vaccine formulated with the Chlamydia trachomatis serovar F, native major outer membrane protein in a nonhuman primate modelVaccination of koalas with a recombinant Chlamydia pecorum major outer membrane protein induces antibodies of different specificity compared to those following a natural live infectionAmphipols stabilize the Chlamydia major outer membrane protein and enhance its protective ability as a vaccineSystemic effector and regulatory immune responses to chlamydial antigens in trachomatous trichiasis.Induction of protection against vaginal shedding and infertility by a recombinant Chlamydia vaccine.A TLR2 agonist is a more effective adjuvant for a Chlamydia major outer membrane protein vaccine than ligands to other TLR and NOD receptors.A live-attenuated chlamydial vaccine protects against trachoma in nonhuman primates.A re-evaluation of the role of B cells in protective immunity to Chlamydia infectionAssociation of tubal factor infertility with elevated antibodies to Chlamydia trachomatis caseinolytic protease P.Intramuscular Immunisation with Chlamydial Proteins Induces Chlamydia trachomatis Specific Ocular Antibodies.Chlamydia muridarum T cell antigens and adjuvants that induce protective immunity in miceImmunization with dendritic cells pulsed ex vivo with recombinant chlamydial protease-like activity factor induces protective immunity against genital chlamydiamuridarum challengeAntibody and Cytokine Responses of Koalas (Phascolarctos cinereus) Vaccinated with Recombinant Chlamydial Major Outer Membrane Protein (MOMP) with Two Different AdjuvantsResolution of Chlamydia trachomatis Infection Is Associated with a Distinct T Cell Response Profile.Toll-like receptor 2-dependent activity of native major outer membrane protein proteosomes of Chlamydia trachomatisA multi-subunit Chlamydia vaccine inducing neutralizing antibodies and strong IFN-γ⁺ CMI responses protects against a genital infection in minipigsVaccination with major outer membrane protein proteosomes elicits protection in mice against a Chlamydia respiratory challenge.Assessment of the role in protection and pathogenesis of the Chlamydia muridarum V-type ATP synthase subunit A (AtpA) (TC0582).The non-human primate model of tuberculosis.Towards a safe and effective chlamydial vaccine: lessons from the eyeTowards a Chlamydia trachomatis vaccine: how close are we?Cell-free production of a functional oligomeric form of a chlamydia major outer membrane protein (MOMP) for vaccine development.Comparison of the nine polymorphic membrane proteins of Chlamydia trachomatis for their ability to induce protective immune responses in mice against a C. muridarum challenge.Demonstration of Persistent Infections and Genome Stability by Whole-Genome Sequencing of Repeat-Positive, Same-Serovar Chlamydia trachomatis Collected From the Female Genital Tract.Update on Chlamydia trachomatis Vaccinology.
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Chlamydia trachomatis native major outer membrane protein induces partial protection in nonhuman primates: implication for a trachoma transmission-blocking vaccine.
description
article científic
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article scientifique
@fr
articolo scientifico
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artigo científico
@pt
bilimsel makale
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scientific article published on June 2009
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Chlamydia trachomatis native m ...... transmission-blocking vaccine.
@en
Chlamydia trachomatis native m ...... transmission-blocking vaccine.
@nl
type
label
Chlamydia trachomatis native m ...... transmission-blocking vaccine.
@en
Chlamydia trachomatis native m ...... transmission-blocking vaccine.
@nl
prefLabel
Chlamydia trachomatis native m ...... transmission-blocking vaccine.
@en
Chlamydia trachomatis native m ...... transmission-blocking vaccine.
@nl
P2093
P2860
P356
P1476
Chlamydia trachomatis native m ...... transmission-blocking vaccine.
@en
P2093
Deborah D Crane
Ellena M Peterson
Harlan D Caldwell
John H Carlson
Laszlo Kari
Luis M de la Maza
Morgan M Goheen
Nathalie Reveneau
Sukumar Pal
William M Whitmire
P2860
P304
P356
10.4049/JIMMUNOL.0804375
P407
P577
2009-06-01T00:00:00Z