LDL receptor-related protein 1: unique tissue-specific functions revealed by selective gene knockout studies - Wikidata - awgldk - TriplyDB

LDL receptor-related protein 1: unique tissue-specific functions revealed by selective gene knockout studies

LDL receptor-related protein 1: unique tissue-specific functions revealed by selective gene knockout studies

http://www.wikidata.org/entity/Q37216064

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LRP-1: a checkpoint for the extracellular matrix proteolysis CD91 interacts with mannan-binding lectin (MBL) through the MBL-associated serine protease-binding site Low density lipoprotein receptor-related protein-1 (LRP1) regulates thrombospondin-2 (TSP2) enhancement of Notch3 signaling Secreted heat shock protein 90alpha induces colorectal cancer cell invasion through CD91/LRP-1 and NF-kappaB-mediated integrin alphaV expression Genetics of migraine in the age of genome-wide association studies Uptake of ANG1005, a novel paclitaxel derivative, through the blood-brain barrier into brain and experimental brain metastases of breast cancer Microglia Ontology and Signaling The Apoe(-/-) mouse model: a suitable model to study cardiovascular and respiratory diseases in the context of cigarette smoke exposure and harm reduction Keratinocyte-Secreted Heat Shock Protein-90alpha: Leading Wound Reepithelialization and Closure Overnutrition Determines LPS Regulation of Mycotoxin Induced Neurotoxicity in Neurodegenerative Diseases The Matricellular Receptor LRP1 Forms an Interface for Signaling and Endocytosis in Modulation of the Extracellular Tumor Environment Impaired vascular-mediated clearance of brain amyloid beta in Alzheimer's disease: the role, regulation and restoration of LRP1 Insulin in the brain: there and back again The low-density lipoprotein receptor-related protein 1 and amyloid-β clearance in Alzheimer's disease Ribosome-inactivating proteins: from plant defense to tumor attack Apolipoprotein E and apolipoprotein E receptors: normal biology and roles in Alzheimer disease Extracellular Hsp90 (eHsp90) as the actual target in clinical trials: intentionally or unintentionally The protective role of prosaposin and its receptors in the nervous system Neuroinflammation: a common pathway in CNS diseases as mediated at the blood-brain barrier Endothelial LRP1 transports amyloid-β(1-42) across the blood-brain barrier Presumed LRP1-targeting transport peptide delivers β-secretase inhibitor to neurons in vitro with limited efficiency Evidence for chemoreceptors with bimodular ligand-binding regions harboring two signal-binding sites LDL receptor and its family members serve as the cellular receptors for vesicular stomatitis virus Taking aim at the extracellular matrix: CCN proteins as emerging therapeutic targets A novel extracellular Hsp90 mediated co-receptor function for LRP1 regulates EphA2 dependent glioblastoma cell invasion LRP1 regulates architecture of the vascular wall by controlling PDGFRbeta-dependent phosphatidylinositol 3-kinase activation Inflammatory mediators promote production of shed LRP1/CD91, which regulates cell signaling and cytokine expression by macrophages A Role for Low Density Lipoprotein Receptor-Related Protein 1 in the Cellular Uptake of Tissue Plasminogen Activator in the Lungs Whole exome sequencing identifies LRP1 as a pathogenic gene in autosomal recessive keratosis pilaris atrophicans Genome-wide association analysis identifies susceptibility loci for migraine without aura.LRP1 expression in microglia is protective during CNS autoimmunity.Generation of a Potent Low Density Lipoprotein Receptor-related Protein 1 (LRP1) Antagonist by Engineering a Stable Form of the Receptor-associated Protein (RAP) D3 Domain Identification of the low density lipoprotein (LDL) receptor-related protein-1 interactome in central nervous system myelin suggests a role in the clearance of necrotic cell debris.Genome-wide association study reveals three susceptibility loci for common migraine in the general population.The tissue-type plasminogen activator-plasminogen activator inhibitor 1 complex promotes neurovascular injury in brain trauma: evidence from mice and humans Conjugation of a brain-penetrant peptide with neurotensin provides antinociceptive properties Internalization by multiple endocytic pathways and lysosomal processing impact maspin-based therapeutics.HIV-1 Tat-induced changes in synaptically-driven network activity adapt during prolonged exposure.The LDL receptor-related protein 1 (LRP1) regulates the PDGF signaling pathway by binding the protein phosphatase SHP-2 and modulating SHP-2- mediated PDGF signaling events.LRP1 receptor controls adipogenesis and is up-regulated in human and mouse obese adipose tissue.

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LDL receptor-related protein 1: unique tissue-specific functions revealed by selective gene knockout studies

http://www.wikidata.org/entity/Q37216064

description

article científic

@ca

article scientifique

@fr

articolo scientifico

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artigo científico

@pt

bilimsel makale

@tr

scientific article published on July 2008

@en

vedecký článok

@sk

vetenskaplig artikel

@sv

videnskabelig artikel

@da

vědecký článek

@cs

name

LDL receptor-related protein 1 ...... elective gene knockout studies

@en

LDL receptor-related protein 1 ...... lective gene knockout studies.

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type

label

LDL receptor-related protein 1 ...... elective gene knockout studies

@en

LDL receptor-related protein 1 ...... lective gene knockout studies.

@nl

prefLabel

LDL receptor-related protein 1 ...... elective gene knockout studies

@en

LDL receptor-related protein 1 ...... lective gene knockout studies.

@nl

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PHYSREV.00033.2007

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Physiological Reviews

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LDL receptor-related protein 1 ...... elective gene knockout studies

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Anna P Lillis

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Dudley K Strickland

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Joanne E Murphy-Ullrich

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Lauren B Van Duyn

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P2860

LRP1 functions as an atheroprotective integrator of TGFbeta and PDFG signals in the vascular wall: implications for Marfan syndrome

A novel protease-docking function of integrin at invadopodia

Insulin-degrading enzyme regulates extracellular levels of amyloid beta-protein by degradation

Isolation and characterization of a high molecular weight glycoprotein from human blood platelets

Beta-secretase cleavage of Alzheimer's amyloid precursor protein by the transmembrane aspartic protease BACE

Interactions of the low density lipoprotein receptor gene family with cytosolic adaptor and scaffold proteins suggest diverse biological functions in cellular communication and signal transduction

Interaction of CED-6/GULP, an adapter protein involved in engulfment of apoptotic cells with CED-1 and CD91/low density lipoprotein receptor-related protein (LRP)

Surface location and high affinity for calcium of a 500-kd liver membrane protein closely related to the LDL-receptor suggest a physiological role as lipoprotein receptor

Interaction of alpha9beta1 integrin with thrombospondin-1 promotes angiogenesis

In vitro interaction of a polypeptide homologous to human Ro/SS-A antigen (calreticulin) with a highly conserved amino acid sequence in the cytoplasmic domain of integrin alpha subunits

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887-918

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scholarly article

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10.1152/PHYSREV.00033.2007

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3

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88

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2008-07-01T00:00:00Z

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5226439

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18626063

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2744109

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