Ionizing radiation stimulates unidentified tyrosine-specific protein kinases in human B-lymphocyte precursors, triggering apoptosis and clonogenic cell death
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Membrane-associated CD19-LYN complex is an endogenous p53-independent and Bc1-2-independent regulator of apoptosis in human B-lineage lymphoma cellsHuman immunodeficiency virus 1 envelope-initiated G2-phase programmed cell deathIonizing radiation acts on cellular membranes to generate ceramide and initiate apoptosisCross-linking the murine heat-stable antigen induces apoptosis in B cell precursors and suppresses the anti-CD40-induced proliferation of mature resting B lymphocytesPhysical and functional interactions between Lyn and p34cdc2 kinases in irradiated human B-cell precursors.Induction of apoptosis and tyrosine phosphorylation of cellular proteins in T cells and non-T cells by stimulation with concanavalin A.Ultraviolet radiation rapidly induces tyrosine phosphorylation and calcium signaling in lymphocytes.Hierarchical and cybernetic nature of biologic systems and their relevance to homeostatic adaptation to low-level exposures to oxidative stress-inducing agents.Membrane-derived second messenger regulates x-ray-mediated tumor necrosis factor alpha gene induction.Activation of the pp90rsk and mitogen-activated serine/threonine protein kinases by ionizing radiation.Tyrosine phosphorylation is a mandatory proximal step in radiation-induced activation of the protein kinase C signaling pathway in human B-lymphocyte precursors.Thiol agents and Bcl-2 identify an alphavirus-induced apoptotic pathway that requires activation of the transcription factor NF-kappa B.Interleukin 7-dependent B lymphocyte precursor cells are ultrasensitive to apoptosis.scid cells are deficient in Ku and replication protein A phosphorylation by the DNA-dependent protein kinase.Tyrphostins reduce chemotherapy-induced intestinal injury in mice: assessment by a biochemical assay.Cellular immune defect caused by postsurgical radiation therapy in patients with head and neck cancer.Kinase cascades regulating entry into apoptosis.The ionizing radiation-induced replication protein A phosphorylation response differs between ataxia telangiectasia and normal human cells.cAMP-induced apoptosis in granulosa cells is associated with up-regulation of P53 and bax and down-regulation of clusterin.Selective phosphotyrosine phosphatase inhibition and increased ceramide formation is associated with B-cell death by apoptosis.Endogenous production of tumour necrosis factor is required for manganese superoxide dismutase expression by irradiation in the human monocytic cell line THP-1.Role of hydroxyl radicals in radiation-induced activation of lyn tyrosine kinase in human B-cell precursors.Exposure of B-lineage lymphoid cells to low energy electromagnetic fields stimulates Lyn kinase.In vivo radiosensitizing effects of recombinant interleukin 6 on radiation resistant BCL-1 B-lineage leukemia cells in a murine syngeneic bone marrow transplant model system.Lineage-specific induction of B cell apoptosis and altered signal transduction by the phosphotyrosine phosphatase inhibitor bis(maltolato)oxovanadium(IV).Radiation studies on B cell differentiation marker CD24/SCLC Cluster-4 antigen expressing and non-expressing lung cancer cell lines and mouse fibroblasts.Purification of a 24-kD protease from apoptotic tumor cells that activates DNA fragmentation.Phorbol esters can protect mouse pre-T cell lines from radiation-induced rapid interphase apoptosis.FK506 augments activation-induced programmed cell death of T lymphocytes in vivo.Defect in Radiation Signal Transduction in Ataxia-telangiectasia.Nitroxides tempol and tempo induce divergent signal transduction pathways in MDA-MB 231 breast cancer cells.Electromagnetic field-induced stimulation of Bruton's tyrosine kinase.Rapid patterning in 2-D cultures of Dictyostelium cells and its relationship to zonal differentiation.Dependence of thymocyte apoptosis on protein kinase C and phospholipase A2A p53-independent Pathway for Activation of WAF1/CIP1 Expression Following Oxidative Stress
P2860
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P2860
Ionizing radiation stimulates unidentified tyrosine-specific protein kinases in human B-lymphocyte precursors, triggering apoptosis and clonogenic cell death
description
article científic
@ca
article scientifique
@fr
articolo scientifico
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artigo científico
@pt
bilimsel makale
@tr
scientific article published on October 1992
@en
vedecký článok
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vetenskaplig artikel
@sv
videnskabelig artikel
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vědecký článek
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name
Ionizing radiation stimulates ...... osis and clonogenic cell death
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Ionizing radiation stimulates ...... sis and clonogenic cell death.
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type
label
Ionizing radiation stimulates ...... osis and clonogenic cell death
@en
Ionizing radiation stimulates ...... sis and clonogenic cell death.
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prefLabel
Ionizing radiation stimulates ...... osis and clonogenic cell death
@en
Ionizing radiation stimulates ...... sis and clonogenic cell death.
@nl
P2093
P2860
P356
P1476
Ionizing radiation stimulates ...... osis and clonogenic cell death
@en
P2093
G L Schieven
J A Ledbetter
J Kirihara
L Tuel-Ahlgren
P2860
P304
P356
10.1073/PNAS.89.19.9005
P407
P577
1992-10-01T00:00:00Z