Putative antirecombinase Srs2 DNA helicase promotes noncrossover homologous recombination avoiding loss of heterozygosity.
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Srs2 promotes Mus81-Mms4-mediated resolution of recombination intermediates.Srs2 promotes synthesis-dependent strand annealing by disrupting DNA polymerase δ-extending D-loopsGenome maintenance in Saccharomyces cerevisiae: the role of SUMO and SUMO-targeted ubiquitin ligases.Mechanism of DNA damage tolerance.Srs2 and Mus81-Mms4 Prevent Accumulation of Toxic Inter-Homolog Recombination Intermediates.Pro-recombination Role of Srs2 Protein Requires SUMO (Small Ubiquitin-like Modifier) but Is Independent of PCNA (Proliferating Cell Nuclear Antigen) Interaction.Regulation of recombination and genomic maintenance.Multifunctional roles of Saccharomyces cerevisiae Srs2 protein in replication, recombination and repair.Rad51 and RecA juxtapose dsDNA ends ready for DNA ligase-catalyzed end-joining under recombinase-suppressive conditions.DNA Damage Tolerance Pathway Choice Through Uls1 Modulation of Srs2 SUMOylation in Saccharomyces cerevisiae.Tight Regulation of Srs2 Helicase Activity Is Crucial for Proper Functioning of DNA Repair Mechanisms.Flap endonuclease overexpression drives genome instability and DNA damage hypersensitivity in a PCNA-dependent manner.Nonfilament-forming RecA dimer catalyzes homologous joint formationThe Main Role of Srs2 in DNA Repair Depends on Its Helicase Activity, Rather than on Its Interactions with PCNA or Rad51
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P2860
Putative antirecombinase Srs2 DNA helicase promotes noncrossover homologous recombination avoiding loss of heterozygosity.
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article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 16 September 2013
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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Putative antirecombinase Srs2 ...... oiding loss of heterozygosity.
@en
Putative antirecombinase Srs2 ...... oiding loss of heterozygosity.
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type
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Putative antirecombinase Srs2 ...... oiding loss of heterozygosity.
@en
Putative antirecombinase Srs2 ...... oiding loss of heterozygosity.
@nl
prefLabel
Putative antirecombinase Srs2 ...... oiding loss of heterozygosity.
@en
Putative antirecombinase Srs2 ...... oiding loss of heterozygosity.
@nl
P2093
P2860
P356
P1476
Putative antirecombinase Srs2 ...... oiding loss of heterozygosity.
@en
P2093
Kohji Kusano
Takehiko Shibata
Tohru Miura
P2860
P304
16067-16072
P356
10.1073/PNAS.1303111110
P407
P577
2013-09-16T00:00:00Z