Long-term activation of TLR3 by poly(I:C) induces inflammation and impairs lung function in mice
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Toll-like receptor ligands LPS and poly (I:C) exacerbate airway hyperresponsiveness in a model of airway allergy in mice, independently of inflammationLL37 and cationic peptides enhance TLR3 signaling by viral double-stranded RNAsLung pathology in fatal novel human influenza A (H1N1) infection.Systemic administration of TLR3 agonist induces IL-7 expression and IL-7-dependent CXCR3 ligand production in the lung.Innate immune responses and neuroepithelial degeneration and regeneration in the mouse olfactory mucosa induced by intranasal administration of Poly(I:C).TLR3 and TLR7 modulate IgE production in antigen induced pulmonary inflammation via influencing IL-4 expression in immune organs.Assessing pulmonary pathology by detailed examination of respiratory function.Intranasal administration of poly(I:C) and LPS in BALB/c mice induces airway hyperresponsiveness and inflammation via different pathwaysTLR-based immune adjuvants.Toll-like receptor 7 stimulates the expression of Epstein-Barr virus latent membrane protein 1TRIF Deficiency does not Affect Severity of Ovalbumin-induced Airway Inflammation in Mice.Orally administered Lactobacillus rhamnosus modulates the respiratory immune response triggered by the viral pathogen-associated molecular pattern poly(I:C)Innate immune activation by the viral PAMP poly I:C potentiates pulmonary graft-versus-host disease after allogeneic hematopoietic cell transplant.Inhaled dsRNA and rhinovirus evoke neutrophilic exacerbation and lung expression of thymic stromal lymphopoietin in allergic mice with established experimental asthmaDouble-stranded RNA attenuates the barrier function of human pulmonary artery endothelial cells.Nasally administered Lactobacillus rhamnosus strains differentially modulate respiratory antiviral immune responses and induce protection against respiratory syncytial virus infectionSkin fibroblasts from individuals with Chediak-Higashi Syndrome (CHS) exhibit hyposensitive immunogenic response.Synergistic Proinflammatory Responses by IL-17A and Toll-Like Receptor 3 in Human Airway Epithelial Cells.Interleukin-17A and Toll-Like Receptor 3 Ligand Poly(I:C) Synergistically Induced Neutrophil Chemoattractant Production by Bronchial Epithelial Cells.Increased expression of upstream TH2-cytokines in a mouse model of viral-induced asthma exacerbation.New insights into the mechanisms of innate immune receptor signalling in fibrosis.Poly(I:C) Induces Human Lung Endothelial Barrier Dysfunction by Disrupting Tight Junction Expression of Claudin-5.Innate Immune Signaling Induces IL-7 Production, Early Inflammatory Responses, and Sjögren's-Like Dacryoadenitis in C57BL/6 Mice.Double-stranded RNA induces molecular and inflammatory signatures that are directly relevant to COPD.Analysis of global gene expression changes in human bronchial epithelial cells exposed to spores of the allergenic fungus, Alternaria alternataMECHANICAL VENTILATION AUGMENTS POLY(I:C)INDUCED LUNG INJURY VIA A WISP1-INTEGRIN β3 DEPENDENT PATHWAY IN MICEPersistence of LPS-induced lung inflammation in surfactant protein-C-deficient micePenehyclidine hydrochloride: a potential drug for treating COPD by attenuating Toll-like receptors.Modulation of Respiratory TLR3-Anti-Viral Response by Probiotic Microorganisms: Lessons Learned from Lactobacillus rhamnosus CRL1505.Association of Single Nucleotide Polymorphisms in Toll-like Receptor Genes With Asthma Risk: A Systematic Review and Meta-analysis.Inhibition of Toll-Like Receptor Signaling as a Promising Therapy for Inflammatory Diseases: A Journey from Molecular to Nano Therapeutics.BRD4 Couples NF-κB/RelA with Airway Inflammation and the IRF-RIG-I Amplification Loop in Respiratory Syncytial Virus Infection.Mucosal vaccine delivery: Current state and a pediatric perspectiveA respiratory syncytial virus persistent-infected cell line system reveals the involvement of SOCS1 in the innate antiviral response.Inhibitory effects of albuterol and fenoterol on RANTES and IP-10 expression in bronchial epithelial cells.Suppressive effects of procaterol on expression of IP-10/CXCL 10 and RANTES/CCL 5 by bronchial epithelial cells.Bifidobacterium breve and Lactobacillus rhamnosus treatment is as effective as budesonide at reducing inflammation in a murine model for chronic asthmaIntranasal immunization with a single dose of the fusion protein formulated with a combination adjuvant induces long-term protective immunity against respiratory syncytial virus.NF-κB Mediates Mesenchymal Transition, Remodeling, and Pulmonary Fibrosis in Response to Chronic Inflammation by Viral RNA Patterns.Versican Deficiency Significantly Reduces Lung Inflammatory Response Induced by Polyinosine-Polycytidylic Acid Stimulation.
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P2860
Long-term activation of TLR3 by poly(I:C) induces inflammation and impairs lung function in mice
description
article científic
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article scientifique
@fr
articolo scientifico
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artigo científico
@pt
bilimsel makale
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scientific article published on June 2009
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Long-term activation of TLR3 by poly
@nl
Long-term activation of TLR3 b ...... impairs lung function in mice
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type
label
Long-term activation of TLR3 by poly
@nl
Long-term activation of TLR3 b ...... impairs lung function in mice
@en
prefLabel
Long-term activation of TLR3 by poly
@nl
Long-term activation of TLR3 b ...... impairs lung function in mice
@en
P2093
P2860
P356
P1433
P1476
Long-term activation of TLR3 b ...... impairs lung function in mice
@en
P2093
Anuk M Das
Devon D Egenolf
Don E Griswold
Holly A Raymond
Jonathan Seideman
Karen A Smalley
Lani R San Mateo
M Lamine Mbow
Nicole C Stowell
Paul A Marsters
P2860
P2888
P356
10.1186/1465-9921-10-43
P577
2009-06-01T00:00:00Z
P5875
P6179
1011120188