15-Hydroxyprostaglandin dehydrogenase inactivation as a mechanism of resistance to celecoxib chemoprevention of colon tumors. - Wikidata - awgldk - TriplyDB

15-Hydroxyprostaglandin dehydrogenase inactivation as a mechanism of resistance to celecoxib chemoprevention of colon tumors.

15-Hydroxyprostaglandin dehydrogenase inactivation as a mechanism of resistance to celecoxib chemoprevention of colon tumors.

http://www.wikidata.org/entity/Q37224133

about

Seminal Fluid-Mediated Inflammation in Physiology and Pathology of the Female Reproductive Tract Multiple drug resistance-associated protein 4 (MRP4), prostaglandin transporter (PGT), and 15-hydroxyprostaglandin dehydrogenase (15-PGDH) as determinants of PGE2 levels in cancer Regulation of immune responses by prostaglandin E2 Targeting inflammation: multiple innovative ways to reduce prostaglandin E₂ Chemoprevention of metastasis Prostaglandin E2-induced colonic secretion in patients with and without colorectal neoplasia Aspirin and the risk of colorectal cancer in relation to the expression of 15-hydroxyprostaglandin dehydrogenase (HPGD)Loss of 15-hydroxyprostaglandin dehydrogenase expression contributes to bladder cancer progression Hypoxia activates the cyclooxygenase-2-prostaglandin E synthase axis PTGER2 overexpression in colorectal cancer is associated with microsatellite instability, independent of CpG island methylator phenotype.Synthetic triterpenoid induces 15-PGDH expression and suppresses inflammation-driven colon carcinogenesis.Eicosanoids and cancer Inactivating mutation in the prostaglandin transporter gene, SLCO2A1, associated with familial digital clubbing, colon neoplasia, and NSAID resistance.Metabolic phenotyping reveals a lipid mediator response to ionizing radiation Primary prevention of colorectal cancer.Mammalian target of rapamycin complex 1 and cyclooxygenase 2 pathways cooperatively exacerbate endometrial cancer.Sulindac reversal of 15-PGDH-mediated resistance to colon tumor chemoprevention with NSAIDs.Genetic variability in key genes in prostaglandin E2 pathway (COX-2, HPGD, ABCC4 and SLCO2A1) and their involvement in colorectal cancer development.The role of COX-2 in intestinal inflammation and colorectal cancer A nonhormonal model for emergency contraception: prostaglandin synthesis inhibitor effects on luteal function and lifespan, a pilot study.Celecoxib pathways: pharmacokinetics and pharmacodynamics.Dual inhibition of vascular endothelial growth factor receptor and epidermal growth factor receptor is an effective chemopreventive strategy in the mouse 4-NQO model of oral carcinogenesis Shh and p50/Bcl3 signaling crosstalk drives pathogenesis of BCCs in Gorlin syndrome.Genetic variation in 15-hydroxyprostaglandin dehydrogenase and colon cancer susceptibility.Improving VEGF-targeted therapies through inhibition of COX-2/PGE2 signaling 15-hydroxyprostaglandin dehydrogenase-derived 15-keto-prostaglandin E2 inhibits cholangiocarcinoma cell growth through interaction with peroxisome proliferator-activated receptor-γ, SMAD2/3, and TAP63 proteins.The Crosstalk of PTGS2 and EGF Signaling Pathways in Colorectal Cancer Colonic 15-PGDH levels are stable across distance and time and are not perturbed by aspirin intervention.A study of prostaglandin pathway genes and interactions with current nonsteroidal anti-inflammatory drug use in colorectal adenoma.Inhibition of 15-hydroxyprostaglandin dehydrogenase by Helicobacter pylori in human gastric carcinogenesis 15-PGDH inhibits hepatocellular carcinoma growth through 15-keto-PGE2/PPARγ-mediated activation of p21WAF1/Cip1.ASPirin Intervention for the REDuction of colorectal cancer risk (ASPIRED): a study protocol for a randomized controlled trial.Influence of Genetic Polymorphisms in Prostaglandin E2 Pathway (COX-2/HPGD/SLCO2A1/ABCC4) on the Risk for Colorectal Adenoma Development and Recurrence after Polypectomy.Prostaglandin catabolic enzymes as tumor suppressors.Multifaceted roles of PGE2 in inflammation and cancer.Three-dimensional culture system identifies a new mode of cetuximab resistance and disease-relevant genes in colorectal cancer.Aspirin and colorectal cancer: the promise of precision chemoprevention.Celecoxib enhances the efficacy of 15-hydroxyprostaglandin dehydrogenase gene therapy in treating murine breast cancer.Colonic Saturated Fatty Acid Concentrations and Expression of COX-1, but not Diet, Predict Prostaglandin E2 in Normal Human Colon Tissue.15-hydroxyprostaglandin dehydrogenase is downregulated and exhibits tumor suppressor activity in gastric cancer.

P2860

Q26742070-E959CFC8-5AF7-4191-8E3D-F212F73D6F1D Q26828414-40DCFB97-8509-4B87-A568-7BDF6C184CD1 Q26849305-8602A818-1E68-4E33-BE15-6CEC30F706F2 Q27008521-9046D7FB-A143-4097-BCB1-E0280895A64D Q28395816-E4B6CFA2-CC72-4071-B30A-3E29A6B86EEA Q33526510-4D5DC9CC-C441-4348-A6B9-A7695BCF2B71 Q33648694-F5D84632-F87D-48A5-BABB-F0D17C509ADC Q33703804-3ACA9FAF-4B03-49F0-80E1-D58F6BD9027B Q33705258-9ABDFF96-F405-495D-A075-B25B76E602EB Q33723499-1CB469F4-24C4-4B61-81F0-8FB2013A218E Q33872540-E7E8F55A-C4E7-4AB8-B87C-EDABC78FD93E Q33966203-812468B6-BABD-481F-8157-6E7D05A00261 Q34017114-A1572F10-E3A9-437D-82CC-32F10F43660A Q34141817-2A56106B-390A-460C-81C3-BA9EFA4EC1F5 Q34165145-91B5BF4E-30EC-49E7-9409-7C1E8D6AB738 Q34299944-C6219B35-FDFF-4269-8E4F-4555AE27F3BD Q35065261-18DEA97B-2B78-4C40-9FE1-63ECF3C2B57E Q35138248-F07067A6-D5C0-4CD7-BE55-7FEC07627E2E Q35234704-AB5D8106-D4B1-4149-A4DA-9A0FDC8A08CE Q35673884-247B4AFD-2549-43CF-AA02-C74408341FCB Q35830941-123426C5-86C2-4FBA-B03F-8F4F398842C2 Q36129640-17CC4EC5-A11D-4E18-8F01-6C7C63DC22CD Q36546794-1665F78D-B642-4C75-9B8E-BBACC57F5B6B Q36867174-B856C693-2CE5-45DC-A925-2B8487CF72A0 Q36997760-CAD6E074-67E5-4DBE-8B6A-F816D67BF304 Q37000533-8D21E0D3-7BD8-49E5-9A8A-47A8674DBE6D Q37148157-8C0918A8-19C5-4F9A-AC13-0114B2932EEB Q37161435-86CD7CE2-D74D-49C1-90E9-FDBD2B4513AF Q37213095-62BBE672-5C8F-4EFA-85F5-2D33BA8AF382 Q37228439-7195A116-3871-44B6-9E36-23CC77EF3AF8 Q37549404-6EA69C4A-4184-4488-8156-BE78A3D07558 Q37618698-19AFD275-7A56-4B0D-9CD1-20EE619D5F61 Q37620344-1EA480AA-BADC-4528-831D-91E9A130DE72 Q37948688-DCD1DEAD-4A4B-4ECF-81EB-302B70E87F2A Q38045226-569F4D6F-9579-4478-B4CB-BE3780D92DF8 Q38711454-3427B0FE-3787-4EAD-9EBB-1EB06CC24AE0 Q38730064-5C83FB91-7E8B-4F4F-B25B-5F22E55119F4 Q39198882-07DC9B3A-67E3-4982-9F0F-7D59F35BAC59 Q39467213-5FAE7663-2A3F-4C26-AD14-50964BDFF585 Q39563381-9212D365-3B9E-436D-AE4C-737B740407CA

P2860

15-Hydroxyprostaglandin dehydrogenase inactivation as a mechanism of resistance to celecoxib chemoprevention of colon tumors.

http://www.wikidata.org/entity/Q37224133

description

article científic

@ca

article scientifique

@fr

articolo scientifico

@it

artigo científico

@pt

bilimsel makale

@tr

scientific article published on 22 May 2009

@en

vedecký článok

@sk

vetenskaplig artikel

@sv

videnskabelig artikel

@da

vědecký článek

@cs

name

15-Hydroxyprostaglandin dehydr ...... emoprevention of colon tumors.

@en

15-Hydroxyprostaglandin dehydr ...... emoprevention of colon tumors.

@nl

type

label

15-Hydroxyprostaglandin dehydr ...... emoprevention of colon tumors.

@en

15-Hydroxyprostaglandin dehydr ...... emoprevention of colon tumors.

@nl

prefLabel

15-Hydroxyprostaglandin dehydr ...... emoprevention of colon tumors.

@en

15-Hydroxyprostaglandin dehydr ...... emoprevention of colon tumors.

@nl

P1433

Q37224133-22CDC2E8-30D1-42E6-9359-AF9980A2E2EC

P1476

Q37224133-3859EB1E-BE7B-4B87-8B3D-47A2A6941BAF

P2093

Q37224133-023BDD7B-1105-4832-9201-7F1B4ADCDA24

Q37224133-0C2315D5-EEA3-4775-A13E-3CE2930FBAAE

Q37224133-0C45CBE7-F839-4FA8-851D-6D0705897E3E

Q37224133-2044097D-63CB-4831-BE10-155F8A207D09

Q37224133-2167D3BD-5A48-4510-A08E-200FE4191C43

Q37224133-5D341CEA-62A1-400A-ADC1-EA18426C2487

Q37224133-63F80BC7-F125-4444-9A84-EF44304DCC0E

Q37224133-686F4B1B-EFC0-46E4-8A25-0BE49F501B0E

Q37224133-7AFE0C5F-A123-4E62-9B6C-C7EC3DB8A662

Q37224133-7CD26AEA-3885-4A15-BCE1-54BA5F235073

P2860

Q37224133-1956A5C8-4593-4D4F-B072-8B68584A8783

Q37224133-20BCF9AE-B11E-4D95-B3BC-98FC9FF1295D

Q37224133-2C699402-1095-4646-817E-D4F1E7B3BFD2

Q37224133-58D419F1-16F1-4D4A-BCF2-A6D937C9B58E

Q37224133-71276E21-9CEA-4DFD-8E9A-856522545B86

Q37224133-7E3922C8-A12F-47DC-9C59-985E4D30822F

Q37224133-9AA5C39F-9609-456C-9E47-5D035CAA8893

Q37224133-AA370564-5CA8-4235-827A-B68ABFF9C654

Q37224133-B835DF6E-70DF-49B6-A237-2E0BC4920065

Q37224133-C10BA0F5-C33C-4427-911E-A234D0046C81

P304

Q37224133-1F7DC486-5314-46A8-B462-59AB73327844

P31

Q37224133-5031B873-9828-4894-B67A-4793DECE2BA8

P356

Q37224133-EDCAF769-1380-4AA6-A9BC-B20CA726F9A5

P407

Q37224133-DCFE7259-0172-4771-9DB4-BD63084E86BE

P433

Q37224133-B7723912-90CC-4743-B4ED-0DBDC25E8753

P478

Q37224133-CD6C24CB-33F1-4850-968F-B9A5CE2BA324

P50

Q37224133-C5319AE0-5FE6-49CA-9753-507FCC3393BF

Q37224133-EFCD0138-F45B-4FA7-B815-9FBE7EE7A1C8

P577

Q37224133-A3493064-FE2C-4499-82F2-E4CD2D00CC6E

P5875

Q37224133-17C7DD45-5D1E-43B3-9D36-D31F50EB4957

P698

Q37224133-96071D26-ECEE-4AE8-ABF1-170C9D2A2D08

P932

Q37224133-62C48E94-7C96-4BE9-8BBB-E9C3715A34C7

P356

PNAS.0902367106

P1433

Proceedings of the National Academy of Sciences of the United States of America

P1476

15-Hydroxyprostaglandin dehydr ...... hemoprevention of colon tumors

@en

P2093

Danielle Liu

http://www.w3.org/2001/XMLSchema#string

Dawn Dawson

http://www.w3.org/2001/XMLSchema#string

Earl Lawrence

http://www.w3.org/2001/XMLSchema#string

Hsin-Hsiung Tai

http://www.w3.org/2001/XMLSchema#string

James Lutterbaugh

http://www.w3.org/2001/XMLSchema#string

Joseph Willis

http://www.w3.org/2001/XMLSchema#string

Min Yan

http://www.w3.org/2001/XMLSchema#string

Monica M Bertagnolli

http://www.w3.org/2001/XMLSchema#string

Peiying Yang

http://www.w3.org/2001/XMLSchema#string

Robert A Newman

http://www.w3.org/2001/XMLSchema#string

P2860

15-Hydroxyprostaglandin dehydrogenase, a COX-2 oncogene antagonist, is a TGF-beta-induced suppressor of human gastrointestinal cancers

Celecoxib for the prevention of sporadic colorectal adenomas

Celecoxib for the prevention of colorectal adenomatous polyps

Aspirin and colon cancer--targeting prevention?

Metabolism of PGE2 by prostaglandin dehydrogenase is essential for remodeling the ductus arteriosus

15-Hydroxyprostaglandin dehydrogenase is down-regulated in colorectal cancer

The effect of celecoxib, a cyclooxygenase-2 inhibitor, in familial adenomatous polyposis

15-Hydroxyprostaglandin dehydrogenase is an in vivo suppressor of colon tumorigenesis.

NSAIDs and cancer prevention: targets downstream of COX-2.

Simultaneous quantification of arachidonic acid metabolites in cultured tumor cells using high-performance liquid chromatography/electrospray ionization tandem mass spectrometry.

P304

9409-9413

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1073/PNAS.0902367106

http://www.w3.org/2001/XMLSchema#string

P407

P433

23

http://www.w3.org/2001/XMLSchema#string

P478

106

http://www.w3.org/2001/XMLSchema#string

P50

Seung-Jae Myung

Jill S Barnholtz-Sloan

P577

2009-05-22T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

26241923

http://www.w3.org/2001/XMLSchema#string

P698

19470469

http://www.w3.org/2001/XMLSchema#string

P932

2695050

http://www.w3.org/2001/XMLSchema#string