Autocatalytic aptazymes enable ligand-dependent exponential amplification of RNA.
about
Evolution in an RNA worldAn isothermal system that couples ligand-dependent catalysis to ligand-independent exponential amplificationHighly efficient self-replicating RNA enzymesRational, modular adaptation of enzyme-free DNA circuits to multiple detection methodsApproaches to the origin of life on Earth.Ligand-dependent exponential amplification of a self-replicating L-RNA enzyme.Synthetic evolving systems that implement a user-specified genetic code of arbitrary designKinetic properties of an RNA enzyme that undergoes self-sustained exponential amplification.Ligand-dependent exponential amplification of self-replicating RNA enzymes.Aptamers for allosteric regulation.Point-of-care nucleic acid detection using nanotechnology.Ligand-dependent ribozymes.A general approach to the design of allosteric, transcription factor-regulated DNAzymes.Real-Time Detection of a Self-Replicating RNA EnzymeNucleic acids: function and potential for abiogenesis.Exploring the emergence of complexity using synthetic replicators.Detection of metal ions (Cu2+, Hg2+) and cocaine by using ligation DNAzyme machinery.An aptazyme-based molecular device that converts a small-molecule input into an RNA output.DNA cross-triggered cascading self-amplification artificial biochemical circuit.
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Autocatalytic aptazymes enable ligand-dependent exponential amplification of RNA.
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article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 22 February 2009
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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Autocatalytic aptazymes enable ligand-dependent exponential amplification of RNA.
@en
Autocatalytic aptazymes enable ligand-dependent exponential amplification of RNA.
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type
label
Autocatalytic aptazymes enable ligand-dependent exponential amplification of RNA.
@en
Autocatalytic aptazymes enable ligand-dependent exponential amplification of RNA.
@nl
prefLabel
Autocatalytic aptazymes enable ligand-dependent exponential amplification of RNA.
@en
Autocatalytic aptazymes enable ligand-dependent exponential amplification of RNA.
@nl
P2860
P356
P1433
P1476
Autocatalytic aptazymes enable ligand-dependent exponential amplification of RNA.
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P2093
Bianca J Lam
Gerald F Joyce
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P2888
P304
P356
10.1038/NBT.1528
P577
2009-02-22T00:00:00Z