Independent prognostic value of BCR-ABL1-like signature and IKZF1 deletion, but not high CRLF2 expression, in children with B-cell precursor ALL. - Wikidata - awgldk - TriplyDB

Independent prognostic value of BCR-ABL1-like signature and IKZF1 deletion, but not high CRLF2 expression, in children with B-cell precursor ALL.

Independent prognostic value of BCR-ABL1-like signature and IKZF1 deletion, but not high CRLF2 expression, in children with B-cell precursor ALL.

http://www.wikidata.org/entity/Q37226741

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New and emerging prognostic and predictive genetic biomarkers in B-cell precursor acute lymphoblastic leukemia Diagnosis and subclassification of acute lymphoblastic leukemia Redefining ALL classification: toward detecting high-risk ALL and implementing precision medicine Childhood acute lymphoblastic leukemia: Integrating genomics into therapy Childhood Acute Lymphoblastic Leukemia: Progress Through Collaboration Venetoclax responses of pediatric ALL xenografts reveal sensitivity of MLL-rearranged leukemia.Tumor suppressors BTG1 and IKZF1 cooperate during mouse leukemia development and increase relapse risk in B-cell precursor acute lymphoblastic leukemia patients.Childhood B-acute lymphoblastic leukemia: a genetic update.Outcomes of children with BCR-ABL1–like acute lymphoblastic leukemia treated with risk-directed therapy based on the levels of minimal residual disease.Targetable kinase-activating lesions in Ph-like acute lymphoblastic leukemia.Association of ITPA genotype with event-free survival and relapse rates in children with acute lymphoblastic leukemia undergoing maintenance therapy Novel gene targets detected by genomic profiling in a consecutive series of 126 adults with acute lymphoblastic leukemia.Expression of Ik6 and Ik8 Isoforms and Their Association with Relapse and Death in Mexican Children with Acute Lymphoblastic Leukemia Prognostic impact of IKZF1 deletion in adults with common B-cell acute lymphoblastic leukemia.Targeting casein kinase II restores Ikaros tumor suppressor activity and demonstrates therapeutic efficacy in high-risk leukemia.A retrospective analysis of treatment-related hospitalization costs of pediatric, adolescent, and young adult acute lymphoblastic leukemia Identification of ETV6-RUNX1-like and DUX4-rearranged subtypes in paediatric B-cell precursor acute lymphoblastic leukaemia.Characterization of pediatric Philadelphia-negative B-cell precursor acute lymphoblastic leukemia with kinase fusions in Japan.Characterization of leukemias with ETV6-ABL1 fusion COBL is a novel hotspot for IKZF1 deletions in childhood acute lymphoblastic leukemia.Pediatric-like therapy for adults with ALL.Pathogenesis and prognostication in acute lymphoblastic leukemia.Risk factors for relapse in childhood acute lymphoblastic leukemia: prediction and prevention.Genomic and pharmacogenetic studies of childhood acute lymphoblastic leukemia.Ikaros and leukaemia.Genomics in acute lymphoblastic leukaemia: insights and treatment implications.Ikaros deletions in BCR-ABL-negative childhood acute lymphoblastic leukemia are associated with a distinct gene expression signature but do not result in intrinsic chemoresistance.Transcription factor networks in B-cell differentiation link development to acute lymphoid leukemia.Driving Toward Precision Medicine for Acute Leukemias: Are We There Yet?Advances in therapy for Philadelphia-positive acute lymphoblastic leukaemia of childhood and adolescence.Genetic analysis of Ikaros target genes and tumor suppressor function in BCR-ABL1+ pre-B ALL.Conserved IKAROS-regulated genes associated with B-progenitor acute lymphoblastic leukemia outcome.Minimal Residual Disease in Acute Lymphoblastic Leukemia: How to Recognize and Treat It.Oligoclonality and new agent evaluation in acute lymphoblastic leukaemia.Therapeutic targeting of IL-7Rα signaling pathways in ALL treatment.Treatment of Childhood Acute Lymphoblastic Leukemia: Prognostic Factors and Clinical Advances.Effect of IKZF1 deletions on signal transduction pathways in Philadelphia chromosome negative pediatric B-cell precursor acute lymphoblastic leukemia (BCP-ALL).Ikaros: Exploiting and targeting the hematopoietic stem cell niche in B-progenitor acute lymphoblastic leukemia.New cellular markers at diagnosis are associated with isolated central nervous system relapse in paediatric B-cell precursor acute lymphoblastic leukaemia.Adults with Philadelphia chromosome-like acute lymphoblastic leukemia frequently have IGH-CRLF2 and JAK2 mutations, persistence of minimal residual disease and poor prognosis

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Independent prognostic value of BCR-ABL1-like signature and IKZF1 deletion, but not high CRLF2 expression, in children with B-cell precursor ALL.

http://www.wikidata.org/entity/Q37226741

description

article científic

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scientific article published on 23 August 2013

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vedecký článok

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vetenskaplig artikel

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vědecký článek

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name

Independent prognostic value o ...... ren with B-cell precursor ALL.

@en

Independent prognostic value o ...... ren with B-cell precursor ALL.

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type

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Independent prognostic value o ...... ren with B-cell precursor ALL.

@en

Independent prognostic value o ...... ren with B-cell precursor ALL.

@nl

prefLabel

Independent prognostic value o ...... ren with B-cell precursor ALL.

@en

Independent prognostic value o ...... ren with B-cell precursor ALL.

@nl

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BLOOD-2012-10-462358

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Independent prognostic value o ...... ren with B-cell precursor ALL.

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Arian van der Veer

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Dimitris Rizopoulos

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Edwin Sonneveld

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Esmé Waanders

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Frank Van Leeuwen

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Hester A De Groot-Kruseman

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Leila Mohammadi Khankahdani

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Lisa J Russell

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Marieke E Willemse

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Martin A Horstmann

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P2860

A subtype of childhood acute lymphoblastic leukaemia with poor treatment outcome: a genome-wide classification study

IKZF1 deletions predict relapse in uniformly treated pediatric precursor B-ALL.

c-Myb and its target Bmi1 are required for p190BCR/ABL leukemogenesis in mouse and human cells

Functional screening identifies CRLF2 in precursor B-cell acute lymphoblastic leukemia.

Rearrangement of CRLF2 is associated with mutation of JAK kinases, alteration of IKZF1, Hispanic/Latino ethnicity, and a poor outcome in pediatric B-progenitor acute lymphoblastic leukemia

IKAROS deletions dictate a unique gene expression signature in patients with adult B-cell acute lymphoblastic leukemia

Stage-specific expression of two neighboring Crlz1 and IgJ genes during B cell development is regulated by their chromatin accessibility and histone acetylation.

Biology, risk stratification, and therapy of pediatric acute leukemias: an update.

Gain-of-function mutations in interleukin-7 receptor-α (IL7R) in childhood acute lymphoblastic leukemias.

Key pathways are frequently mutated in high-risk childhood acute lymphoblastic leukemia: a report from the Children's Oncology Group.

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2622-2629

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scholarly article

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10.1182/BLOOD-2012-10-462358

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Christine J Harrison

Gabriele Escherich

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2013-08-23T00:00:00Z

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