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Centrosomal localization of the psoriasis candidate gene product, CCHCR1, supports a role in cytoskeletal organizationMacro histone H2A1.2 (macroH2A1) protein suppresses mitotic kinase VRK1 during interphaseAction mechanisms of histone deacetylase inhibitors in the treatment of hematological malignanciesNon-centrosomal TPX2-Dependent Regulation of the Aurora A Kinase: Functional Implications for Healthy and Pathological Cell DivisionAurora-A Kinase as a Promising Therapeutic Target in CancerMelanoma: oncogenic drivers and the immune systemPreclinical Childhood Sarcoma Models: Drug Efficacy Biomarker Identification and ValidationMultiple Molecular Pathways in Melanomagenesis: Characterization of Therapeutic TargetsCell division: control of the chromosomal passenger complex in time and spaceAurora at the pole and equator: overlapping functions of Aurora kinases in the mitotic spindleCurrent and future trials of targeted therapies in cutaneous melanomaJoint modeling of cell and nuclear shape variationAurora A Kinase Inhibition Selectively Synergizes with Histone Deacetylase Inhibitor through Cytokinesis Failure in T-cell Lymphoma.Two TPX2-dependent switches control the activity of Aurora AContext-Dependent Cell Cycle Checkpoint Abrogation by a Novel Kinase InhibitorDevelopment of o -Chlorophenyl Substituted Pyrimidines as Exceptionally Potent Aurora Kinase InhibitorsCrystal Structure of Human Aurora B in Complex with INCENP and VX-680Alisertib induces cell cycle arrest and autophagy and suppresses epithelial-to-mesenchymal transition involving PI3K/Akt/mTOR and sirtuin 1-mediated signaling pathways in human pancreatic cancer cellsPro-apoptotic and pro-autophagic effects of the Aurora kinase A inhibitor alisertib (MLN8237) on human osteosarcoma U-2 OS and MG-63 cells through the activation of mitochondria-mediated pathway and inhibition of p38 MAPK/PI3K/Akt/mTOR signaling patInhibition of Aurora kinase B is important for biologic activity of the dual inhibitors of BCR-ABL and Aurora kinases R763/AS703569 and PHA-739358 in BCR-ABL transformed cellsAurora kinase-A deficiency during skin development impairs cell division and stratificationCdk5rap2 regulates centrosome function and chromosome segregation in neuronal progenitorsWidespread genomic instability mediated by a pathway involving glycoprotein Ib alpha and Aurora B kinase.Zwint-1 is a novel Aurora B substrate required for the assembly of a dynein-binding platform on kinetochores.Unsupervised feature construction and knowledge extraction from genome-wide assays of breast cancer with denoising autoencodersDeregulated ERK1/2 MAP kinase signaling promotes aneuploidy by a Fbxw7β-Aurora A pathwayMeta-analysis of Aurora Kinase A (AURKA) Expression Data Reveals a Significant Correlation Between Increased AURKA Expression and Distant Metastases in Human ER-positive Breast Cancers.Benzo[e]pyridoindoles, novel inhibitors of the aurora kinases.Phase I study of the aurora A kinase inhibitor alisertib with induction chemotherapy in patients with acute myeloid leukemia.A phase 2 study of alisertib (MLN8237) in recurrent or persistent uterine leiomyosarcoma: An NRG Oncology/Gynecologic Oncology Group study 0231D.Safeguarding entry into mitosis: the antephase checkpoint.Arsenic treatment increase Aurora-A overexpression through E2F1 activation in bladder cells.Characterization of the genomic features and expressed fusion genes in micropapillary carcinomas of the breast.Coordinating cellular events during spermatogenesis: a biochemical modelVisualizing histone modifications in living cells: spatiotemporal dynamics of H3 phosphorylation during interphase.Bone-in-culture array as a platform to model early-stage bone metastases and discover anti-metastasis therapiesAnalysis of genetic copy number changes in cervical disease progression.Aurora A orchestrates entosis by regulating a dynamic MCAK-TIP150 interactionMaternal embryonic leucine zipper kinase: key kinase for stem cell phenotype in glioma and other cancers.AURKA mRNA expression is an independent predictor of poor prognosis in patients with non-small cell lung cancer
P2860
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P2860
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 23 July 2008
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
The Aurora kinase family in cell division and cancer.
@en
The Aurora kinase family in cell division and cancer.
@nl
type
label
The Aurora kinase family in cell division and cancer.
@en
The Aurora kinase family in cell division and cancer.
@nl
prefLabel
The Aurora kinase family in cell division and cancer.
@en
The Aurora kinase family in cell division and cancer.
@nl
P1476
The Aurora kinase family in cell division and cancer
@en
P2093
Susanne M A Lens
P356
10.1016/J.BBCAN.2008.07.003
P407
P50
P577
2008-07-23T00:00:00Z