A new hERG allosteric modulator rescues genetic and drug-induced long-QT syndrome phenotypes in cardiomyocytes from isogenic pairs of patient induced pluripotent stem cells.
about
Modeling Inherited Arrhythmia Disorders Using Induced Pluripotent Stem Cell-Derived Cardiomyocytes.Three-dimensional cardiac microtissues composed of cardiomyocytes and endothelial cells co-differentiated from human pluripotent stem cells.From iPSC towards cardiac tissue-a road under construction.Electrophysiological Analysis of human Pluripotent Stem Cell-derived Cardiomyocytes (hPSC-CMs) Using Multi-electrode Arrays (MEAs)A new era of disease modeling and drug discovery using induced pluripotent stem cells.Integrating cardiomyocytes from human pluripotent stem cells in safety pharmacology: has the time come?Perspectives and Challenges of Pluripotent Stem Cells in Cardiac Arrhythmia Research.Human iPSC-Derived Cardiomyocytes for Investigation of Disease Mechanisms and Therapeutic Strategies in Inherited Arrhythmia Syndromes: Strengths and Limitations.Human pluripotent stem cell models of cardiac disease: from mechanisms to therapies.3D Bioprinting and In Vitro Cardiovascular Tissue Modeling.Recent advances in understanding and prevention of sudden cardiac death.Drug-Mediated Shortening of Action Potentials in LQTS2 Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes.Ajmaline blocks INa and IKr without eliciting differences between Brugada syndrome patient and control human pluripotent stem cell-derived cardiac clusters.MUSCLEMOTION: A Versatile Open Software Tool to Quantify Cardiomyocyte and Cardiac Muscle Contraction In Vitro and In Vivo.On-chip spatiotemporal electrophysiological analysis of human stem cell derived cardiomyocytes enables quantitative assessment of proarrhythmia in drug development
P2860
Q33704567-24CC65FF-0FB2-45E6-97E8-039C8007E177Q37711224-EF52C797-4CD4-45E0-B6D2-4FDD7FDF02B0Q38675863-EF2D0FB3-F581-45B5-AB65-C79AF4766CD4Q38750884-64EDB335-3C70-4467-AFE6-1FABBAF47D3EQ38786732-F18A0BE3-1CED-4883-AC3A-3E367D38C3D0Q38819976-C7C51AC7-DCB0-4194-9571-50F9037671CAQ39144910-F7EB6D61-BAA2-45A0-9BD4-2A0D3CC66120Q39443185-D1A62EBB-0DFB-4FD5-874C-019D8C2504EBQ41664792-DA2F18D3-0679-4F01-979C-9D9BF3B97D6EQ41670153-D4FE5CA0-00D2-45A0-BBDE-96A7DC506123Q42353680-B8769E92-1D31-49E4-99A8-0596625F91D7Q47141643-6A935BBA-6EB1-4140-9BEB-606B2BB2E4E4Q47144807-5165F160-2561-462A-AA9F-967462F96D3DQ47241525-171B48D3-9B9B-4544-A12B-BC4E4EDAEC77Q59126210-74AB1151-EAC6-4409-8A7C-54AF3F897BEC
P2860
A new hERG allosteric modulator rescues genetic and drug-induced long-QT syndrome phenotypes in cardiomyocytes from isogenic pairs of patient induced pluripotent stem cells.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 28 July 2016
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
A new hERG allosteric modulato ...... nduced pluripotent stem cells.
@en
A new hERG allosteric modulato ...... nduced pluripotent stem cells.
@nl
type
label
A new hERG allosteric modulato ...... nduced pluripotent stem cells.
@en
A new hERG allosteric modulato ...... nduced pluripotent stem cells.
@nl
prefLabel
A new hERG allosteric modulato ...... nduced pluripotent stem cells.
@en
A new hERG allosteric modulato ...... nduced pluripotent stem cells.
@nl
P2093
P2860
P50
P356
P1476
A new hERG allosteric modulato ...... nduced pluripotent stem cells.
@en
P2093
Dorien Ward-van Oostwaard
Jacobus Pd van Veldhoven
P2860
P304
P356
10.15252/EMMM.201606260
P577
2016-07-28T00:00:00Z