Neurotoxic thioether adducts of 3,4-methylenedioxymethamphetamine identified in human urine after ecstasy ingestion - Wikidata - awgldk - TriplyDB

Neurotoxic thioether adducts of 3,4-methylenedioxymethamphetamine identified in human urine after ecstasy ingestion

Neurotoxic thioether adducts of 3,4-methylenedioxymethamphetamine identified in human urine after ecstasy ingestion

http://www.wikidata.org/entity/Q37233828

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3,4-methylenedioxymethamphetamine (MDMA): current perspectives The influence of genetic and environmental factors among MDMA users in cognitive performance Clinical pharmacology of 3,4-methylenedioxymethamphetamine (MDMA, "ecstasy"): the influence of gender and genetics (CYP2D6, COMT, 5-HTT)Catechol-o-methyltransferase and 3,4-({+/-})-methylenedioxymethamphetamine toxicity.In vitro metabolism of 3,4-methylenedioxymethamphetamine in human hepatocytes.Synthesis and neurotoxicity profile of 2,4,5-trihydroxymethamphetamine and its 6-(N-acetylcystein-S-yl) conjugate Studies of (±)-3,4-methylenedioxymethamphetamine (MDMA) metabolism and disposition in rats and mice: relationship to neuroprotection and neurotoxicity profile Further studies on the role of metabolites in (+/-)-3,4-methylenedioxymethamphetamine-induced serotonergic neurotoxicity.Pharmacokinetics and pharmacodynamics of 3,4-methylenedioxymethamphetamine (MDMA): interindividual differences due to polymorphisms and drug-drug interactions.A convenient biomimetic synthesis of optically active putative neurotoxic metabolites of MDMA ("ecstasy") from R-(-)- and S-(+)-N-methyl-α-methyldopamine precursors.MDMA, methamphetamine, and CYP2D6 pharmacogenetics: what is clinically relevant?A one-generation reproductive toxicity study of 3,4-methylenedioxy-n-methamphetamine (MDMA, Ecstasy), an amphetamine derivative, in C57BL/6 mice.Sex differences in 3,4-methylenedioxymethamphetamine (MDMA; ecstasy)-induced cytochrome P450 2D6 inhibition in humans.

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P2860

Neurotoxic thioether adducts of 3,4-methylenedioxymethamphetamine identified in human urine after ecstasy ingestion

http://www.wikidata.org/entity/Q37233828

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article científic

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article scientifique

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articolo scientifico

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artigo científico

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bilimsel makale

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scientific article published on 06 April 2009

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vedecký článok

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vetenskaplig artikel

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videnskabelig artikel

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vědecký článek

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name

Neurotoxic thioether adducts o ...... urine after ecstasy ingestion

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Neurotoxic thioether adducts o ...... urine after ecstasy ingestion

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Neurotoxic thioether adducts o ...... urine after ecstasy ingestion.

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Drug Metabolism and Disposition

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Neurotoxic thioether adducts o ...... urine after ecstasy ingestion

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Brian O'Mathúna

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Bruno Almeida

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Jose Antonio Pascual

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Magí Farré

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Nieves Pizarro

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Serrine S Lau

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Terrence J Monks

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Ximena Perfetti

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P2860

Functional analysis of genetic variation in catechol-O-methyltransferase (COMT): effects on mRNA, protein, and enzyme activity in postmortem human brain

Metabolism of a glutathione conjugate of 2-hydroxyoestradiol-17 in the adult male rat

Toxicokinetics and analytical toxicology of amphetamine-derived designer drugs ('Ecstasy')

(+/-)3,4-Methylenedioxymethamphetamine ('Ecstasy')-induced serotonin neurotoxicity: studies in animals.

Human pharmacology of MDMA: pharmacokinetics, metabolism, and disposition.

The pharmacology and clinical pharmacology of 3,4-methylenedioxymethamphetamine (MDMA, "ecstasy").

2,5-Bis-(glutathion-S-yl)-alpha-methyldopamine, a putative metabolite of (+/-)-3,4-methylenedioxyamphetamine, decreases brain serotonin concentrations.

Recreational Ecstasy/MDMA, the serotonin syndrome, and serotonergic neurotoxicity.

Differences between the mechanism of action of MDMA, MBDB, and the classic hallucinogens. Identification of a new therapeutic class: entactogens.

The influence of sex on pharmacokinetics.

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scholarly article

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10.1124/DMD.108.026393

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7

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Elisabet Cuyàs

Manuela Pellegrini

Rafael de la Torre

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2009-04-06T00:00:00Z

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