Neurotoxic thioether adducts of 3,4-methylenedioxymethamphetamine identified in human urine after ecstasy ingestion
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3,4-methylenedioxymethamphetamine (MDMA): current perspectivesThe influence of genetic and environmental factors among MDMA users in cognitive performanceClinical pharmacology of 3,4-methylenedioxymethamphetamine (MDMA, "ecstasy"): the influence of gender and genetics (CYP2D6, COMT, 5-HTT)Catechol-o-methyltransferase and 3,4-({+/-})-methylenedioxymethamphetamine toxicity.In vitro metabolism of 3,4-methylenedioxymethamphetamine in human hepatocytes.Synthesis and neurotoxicity profile of 2,4,5-trihydroxymethamphetamine and its 6-(N-acetylcystein-S-yl) conjugateStudies of (±)-3,4-methylenedioxymethamphetamine (MDMA) metabolism and disposition in rats and mice: relationship to neuroprotection and neurotoxicity profileFurther studies on the role of metabolites in (+/-)-3,4-methylenedioxymethamphetamine-induced serotonergic neurotoxicity.Pharmacokinetics and pharmacodynamics of 3,4-methylenedioxymethamphetamine (MDMA): interindividual differences due to polymorphisms and drug-drug interactions.A convenient biomimetic synthesis of optically active putative neurotoxic metabolites of MDMA ("ecstasy") from R-(-)- and S-(+)-N-methyl-α-methyldopamine precursors.MDMA, methamphetamine, and CYP2D6 pharmacogenetics: what is clinically relevant?A one-generation reproductive toxicity study of 3,4-methylenedioxy-n-methamphetamine (MDMA, Ecstasy), an amphetamine derivative, in C57BL/6 mice.Sex differences in 3,4-methylenedioxymethamphetamine (MDMA; ecstasy)-induced cytochrome P450 2D6 inhibition in humans.
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P2860
Neurotoxic thioether adducts of 3,4-methylenedioxymethamphetamine identified in human urine after ecstasy ingestion
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article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 06 April 2009
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Neurotoxic thioether adducts o ...... urine after ecstasy ingestion
@en
Neurotoxic thioether adducts o ...... urine after ecstasy ingestion.
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type
label
Neurotoxic thioether adducts o ...... urine after ecstasy ingestion
@en
Neurotoxic thioether adducts o ...... urine after ecstasy ingestion.
@nl
prefLabel
Neurotoxic thioether adducts o ...... urine after ecstasy ingestion
@en
Neurotoxic thioether adducts o ...... urine after ecstasy ingestion.
@nl
P2093
P2860
P50
P356
P1476
Neurotoxic thioether adducts o ...... urine after ecstasy ingestion
@en
P2093
Brian O'Mathúna
Bruno Almeida
Jose Antonio Pascual
Magí Farré
Nieves Pizarro
Serrine S Lau
Terrence J Monks
Ximena Perfetti
P2860
P304
P356
10.1124/DMD.108.026393
P577
2009-04-06T00:00:00Z