Steap4 plays a critical role in osteoclastogenesis in vitro by regulating cellular iron/reactive oxygen species (ROS) levels and cAMP response element-binding protein (CREB) activation.
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Iron overload induced death of osteoblasts in vitro: involvement of the mitochondrial apoptotic pathway.Transcriptome analysis illuminates the nature of the intracellular interaction in a vertebrate-algal symbiosis.Downregulation of Notch modulators, tetraspanin 5 and 10, inhibits osteoclastogenesis in vitro.Characterisation of Transcriptional Changes in the Spinal Cord of the Progressive Experimental Autoimmune Encephalomyelitis Biozzi ABH Mouse Model by RNA Sequencing.Sirtuin1 Suppresses Osteoclastogenesis by Deacetylating FoxOs.Genetics of glucocorticoid-associated osteonecrosis in children with acute lymphoblastic leukemiaNRROS Negatively Regulates Osteoclast Differentiation by Inhibiting RANKL-Mediated NF-N:B and Reactive Oxygen Species Pathways.Alternative NF-κB Regulates RANKL-Induced Osteoclast Differentiation and Mitochondrial Biogenesis via Independent MechanismsPLEKHM1/DEF8/RAB7 complex regulates lysosome positioning and bone homeostasis.LIS1 Regulates Osteoclastogenesis through Modulation of M-SCF and RANKL Signaling Pathways and CDC42.STAMPing into Mitochondria."Pumping iron"-how macrophages handle iron at the systemic, microenvironmental, and cellular levelsMacrophages: central regulators of iron balance.NADPH oxidases in bone homeostasis and osteoporosis.Reactive oxygen species and oxidative stress in osteoclastogenesis, skeletal aging and bone diseases.Insights in the etiopathology of galactosyltransferase II (GalT-II) deficiency from transcriptome-wide expression profiling of skin fibroblasts of two sisters with compound heterozygosity for two novel B3GALT6 mutations.Molecular regulation of cellular iron balance.Bone Cell Bioenergetics and Skeletal Energy Homeostasis.Hungry ironyRANKL (Receptor Activator of NFκB Ligand) Produced by Osteocytes Is Required for the Increase in B Cells and Bone Loss Caused by Estrogen Deficiency in Mice.Cryo-EM structures of human STEAP4 reveal mechanism of iron(III) reduction
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Steap4 plays a critical role in osteoclastogenesis in vitro by regulating cellular iron/reactive oxygen species (ROS) levels and cAMP response element-binding protein (CREB) activation.
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 29 August 2013
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Steap4 plays a critical role i ...... ing protein (CREB) activation.
@en
Steap4 plays a critical role i ...... r iron/reactive oxygen species
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type
label
Steap4 plays a critical role i ...... ing protein (CREB) activation.
@en
Steap4 plays a critical role i ...... r iron/reactive oxygen species
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prefLabel
Steap4 plays a critical role i ...... ing protein (CREB) activation.
@en
Steap4 plays a critical role i ...... r iron/reactive oxygen species
@nl
P2093
P2860
P356
P1476
Steap4 plays a critical role i ...... ing protein (CREB) activation.
@en
P2093
Haibo Zhao
Shiqiao Ye
Stavros C Manolagas
Toshifumi Fujiwara
P2860
P304
30064-30074
P356
10.1074/JBC.M113.478750
P407
P577
2013-08-29T00:00:00Z