PLC-gamma2 is essential for formation and maintenance of memory B cells
about
Molecular programming of B cell memoryProgramming the magnitude and persistence of antibody responses with innate immunity.Intrinsic differences in the initiation of B cell receptor signaling favor responses of human IgG(+) memory B cells over IgM(+) naive B cells.The CXCR4 mutations in WHIM syndrome impair the stability of the T-cell immunologic synapseB-cell signaling networks reveal a negative prognostic human lymphoma cell subset that emerges during tumor progressionMemory B cells.The immunoglobulin tail tyrosine motif upgrades memory-type BCRs by incorporating a Grb2-Btk signalling module.The hierarchical process of differentiation of long-lived antibody-secreting cells is dependent on integrated signals derived from antigen and IL-17A.Adaptive immunity suppresses formation and progression of diethylnitrosamine-induced liver cancerReactivation of IgG-switched memory B cells by BCR-intrinsic signal amplification promotes IgG antibody production.Rheumatoid factor B cell memory leads to rapid, switched antibody-forming cell responses.Negative control of mast cell degranulation and the anaphylactic response by the phosphatase lipin1Distinction of the memory B cell response to cognate antigen versus bystander inflammatory signals.The discovery of novel experimental therapies for inflammatory arthritis.From vaccines to memory and back.Through a glass less darkly: apoptosis and the germinal center response to antigen.The Memory Function of the B Cell Antigen Receptor.Differing Requirements for MALT1 Function in Peripheral B Cell Survival and Differentiation.Targeting Gene Function in Germinal Center B Cells: A Practical Approach.Critical role of SAP in progression and reactivation but not maintenance of T cell-dependent humoral immunity.CXCL12 Mediates Aberrant Costimulation of B Lymphocytes in Warts, Hypogammaglobulinemia, Infections, Myelokathexis Immunodeficiency.Spermatogenesis arrest caused by conditional deletion of Hsp90α in adult mice.Modulation of Igβ is essential for the B cell selection in germinal centerTyrosine kinase inhibitors impair B-cell immune responses in CML through off-target inhibition of kinases important for cell signaling.PI(4,5)P2 determines the threshold of mechanical force-induced B cell activation.
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P2860
PLC-gamma2 is essential for formation and maintenance of memory B cells
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 09 March 2009
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
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vědecký článek
@cs
name
PLC-gamma2 is essential for formation and maintenance of memory B cells
@en
PLC-gamma2 is essential for formation and maintenance of memory B cells.
@nl
type
label
PLC-gamma2 is essential for formation and maintenance of memory B cells
@en
PLC-gamma2 is essential for formation and maintenance of memory B cells.
@nl
prefLabel
PLC-gamma2 is essential for formation and maintenance of memory B cells
@en
PLC-gamma2 is essential for formation and maintenance of memory B cells.
@nl
P2093
P2860
P356
P1476
PLC-gamma2 is essential for formation and maintenance of memory B cells
@en
P2093
Masaki Hikida
Noriko Takahashi
Stefano Casola
Tomohiro Kaji
Tomohiro Kurosaki
Toshitada Takemori
P2860
P304
P356
10.1084/JEM.20082100
P407
P577
2009-03-09T00:00:00Z