MicroRNA-100/99a, deregulated in acute lymphoblastic leukaemia, suppress proliferation and promote apoptosis by regulating the FKBP51 and IGF1R/mTOR signalling pathways
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The functional role of microRNA in acute lymphoblastic leukemia: relevance for diagnosis, differential diagnosis, prognosis, and therapySteroid Receptor-Associated Immunophilins: A Gateway to Steroid SignallingEctopic microRNA-150-5p transcription sensitizes glucocorticoid therapy response in MM1S multiple myeloma cells but fails to overcome hormone therapy resistance in MM1R cellsDeep RNA sequencing reveals that microRNAs play a key role in lactation in rats.Understanding thrombocytopenia: physiological role of microRNA in survival of neonatal megakaryocytes.Integrative Analysis of MicroRNA-Mediated Gene Signatures and Pathways Modulating White Blood Cell Count in Childhood Acute Lymphoblastic Leukemia.Long noncoding RNA ANRIL indicates a poor prognosis of gastric cancer and promotes tumor growth by epigenetically silencing of miR-99a/miR-449aA novel small-molecule compound diaporine A inhibits non-small cell lung cancer growth by regulating miR-99a/mTOR signaling.MicroRNA-100 promotes the autophagy of hepatocellular carcinoma cells by inhibiting the expression of mTOR and IGF-1R.Profiling the microRNA Expression in Human iPS and iPS-derived Retinal Pigment Epithelium.Downregulation of microRNA-100 enhances the ICMT-Rac1 signaling and promotes metastasis of hepatocellular carcinoma cells.MicroRNA-139-5p inhibits cell proliferation and invasion by targeting insulin-like growth factor 1 receptor in human non-small cell lung cancer.Sarcoma Cell Line Screen of Oncology Drugs and Investigational Agents Identifies Patterns Associated with Gene and microRNA ExpressionChanges in apoptotic microRNA and mRNA expression profiling in Caenorhabditis elegans during the Shenzhou-8 missionMicroRNAs 99b-5p/100-5p Regulated by Endoplasmic Reticulum Stress are Involved in Abeta-Induced Pathologies.Genome-wide screen identified let-7c/miR-99a/miR-125b regulating tumor progression and stem-like properties in cholangiocarcinomaPrognostic significance of microRNA-100 in solid tumors: an updated meta-analysis.Type I insulin-like growth factor receptor signaling in hematological malignancies.Pharmacogenetics of childhood acute lymphoblastic leukemia.MicroRNAs in adrenal tumors: relevance for pathogenesis, diagnosis, and therapy.Potential role of miR-100 in cancer diagnosis, prognosis, and therapy.FK506 binding protein 51 integrates pathways of adaptation: FKBP51 shapes the reactivity to environmental change.The microRNA-99 family modulates hepatitis B virus replication by promoting IGF-1R/PI3K/Akt/mTOR/ULK1 signaling-induced autophagy.Co-targeting of IGF1R/mTOR pathway by miR-497 and miR-99a impairs hepatocellular carcinoma developmentA Perturbed MicroRNA Expression Pattern Characterizes Embryonic Neural Stem Cells Derived from a Severe Mouse Model of Spinal Muscular Atrophy (SMA).Altered expression and editing of miRNA-100 regulates iTreg differentiation.miR-590 promotes cell proliferation and invasion in T-cell acute lymphoblastic leukaemia by inhibiting RB1.Pooling-analysis for diagnostic and prognostic value of MiRNA-100 in various cancers.MiR-99a suppresses proliferation, migration and invasion of esophageal squamous cell carcinoma cells through inhibiting the IGF1R signaling pathway.High miR-100 expression is associated with aggressive features and modulates TORC1 complex activation in lung carcinoids.Biological Aspects of mTOR in Leukemia
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MicroRNA-100/99a, deregulated in acute lymphoblastic leukaemia, suppress proliferation and promote apoptosis by regulating the FKBP51 and IGF1R/mTOR signalling pathways
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 12 September 2013
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
MicroRNA-100/99a, deregulated ...... IGF1R/mTOR signalling pathways
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MicroRNA-100/99a, deregulated ...... GF1R/mTOR signalling pathways.
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type
label
MicroRNA-100/99a, deregulated ...... IGF1R/mTOR signalling pathways
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MicroRNA-100/99a, deregulated ...... GF1R/mTOR signalling pathways.
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prefLabel
MicroRNA-100/99a, deregulated ...... IGF1R/mTOR signalling pathways
@en
MicroRNA-100/99a, deregulated ...... GF1R/mTOR signalling pathways.
@nl
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P2860
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MicroRNA-100/99a, deregulated ...... IGF1R/mTOR signalling pathways
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10.1038/BJC.2013.562
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2013-09-12T00:00:00Z