Longer lifespan in male mice treated with a weakly estrogenic agonist, an antioxidant, an α-glucosidase inhibitor or a Nrf2-inducer. - Wikidata - awgldk - TriplyDB

Longer lifespan in male mice treated with a weakly estrogenic agonist, an antioxidant, an α-glucosidase inhibitor or a Nrf2-inducer.

Longer lifespan in male mice treated with a weakly estrogenic agonist, an antioxidant, an α-glucosidase inhibitor or a Nrf2-inducer.

http://www.wikidata.org/entity/Q37235568

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NRF2 deficiency replicates transcriptomic changes in Alzheimer's patients and worsens APP and TAU pathology.Fish oil supplements, longevity and aging Machine learning for predicting lifespan-extending chemical compounds Nutrition, metabolism, and targeting aging in nonhuman primates.Cellular Senescence: A Translational Perspective.Nrf2 as a target for prevention of age-related and diabetic cataracts by against oxidative stress.Meta-Analysis of 29 Experiments Evaluating the Effects of Rapamycin on Life Span in the Laboratory Mouse.Anti-aging drugs reduce hypothalamic inflammation in a sex-specific manner.NIA Interventions Testing Program: Investigating Putative Aging Intervention Agents in a Genetically Heterogeneous Mouse Model The Role of the Nrf2/ARE Antioxidant System in Preventing Cardiovascular Diseases.Targeting neuroinflammation - a potential for anti-aging interventions.Hydralazine induces stress resistance and extends C. elegans lifespan by activating the NRF2/SKN-1 signalling pathway.Sex differences in lifespan extension with acarbose and 17-α estradiol: gonadal hormones underlie male-specific improvements in glucose tolerance and mTORC2 signaling.Health benefits of late-onset metformin treatment every other week in mice.Drug repurposing for the treatment of glioblastoma multiforme.17α-estradiol acts through hypothalamic pro-opiomelanocortin expressing neurons to reduce feeding behavior.Metformin reduces glucose intolerance caused by rapamycin treatment in genetically heterogeneous female mice.Hormone actions controlling sex-specific life-extension.Sex-dependent Differences in Liver and Gut Metabolomic Profiles With Acarbose and Calorie Restriction in C57BL/6 Mice.Geroscience and the trans-NIH Geroscience Interest Group, GSIG.Influence of Nrf2 activators on subcellular skeletal muscle protein and DNA synthesis rates after 6 weeks of milk protein feeding in older adults.Targeting glucose metabolism for healthy aging.Late-life targeting of the IGF-1 receptor improves healthspan and lifespan in female mice.Royal Jelly Delays Motor Functional Impairment During Aging in Genetically Heterogeneous Male Mice Activation of Nrf2 in the liver is associated with stress resistance mediated by suppression of the growth hormone-regulated STAT5b transcription factor Effects of long-term dietary administration of estrogen receptor-beta agonist diarylpropionitrile on ovariectomized female ICR (CD-1) mice

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Longer lifespan in male mice treated with a weakly estrogenic agonist, an antioxidant, an α-glucosidase inhibitor or a Nrf2-inducer.

http://www.wikidata.org/entity/Q37235568

description

article científic

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article scientifique

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articolo scientifico

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artigo científico

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bilimsel makale

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scientific article published on 16 June 2016

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vedecký článok

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vetenskaplig artikel

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videnskabelig artikel

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vědecký článek

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name

Longer lifespan in male mice t ...... e inhibitor or a Nrf2-inducer.

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Longer lifespan in male mice t ...... e inhibitor or a Nrf2-inducer.

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type

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Longer lifespan in male mice t ...... e inhibitor or a Nrf2-inducer.

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Longer lifespan in male mice t ...... e inhibitor or a Nrf2-inducer.

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Longer lifespan in male mice t ...... e inhibitor or a Nrf2-inducer.

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Longer lifespan in male mice t ...... se inhibitor or a Nrf2-inducer

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Adam Antebi

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Adam B Salmon

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Arlan Richardson

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Benjamin F Miller

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Clinton M Astle

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David E Harrison

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Elizabeth Fernandez

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G Ed Rainger

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James F Nelson

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James W Simpkins

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P2860

Protandim, a fundamentally new antioxidant approach in chemoprevention using mouse two-stage skin carcinogenesis as a model

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Role of AMP-activated protein kinase in mechanism of metformin action

Rapamycin, but not resveratrol or simvastatin, extends life span of genetically heterogeneous mice

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Rapamycin fed late in life extends lifespan in genetically heterogeneous mice

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Rapamycin-mediated lifespan increase in mice is dose and sex dependent and metabolically distinct from dietary restriction

Metformin induces a dietary restriction-like state and the oxidative stress response to extend C. elegans Healthspan via AMPK, LKB1, and SKN-1

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872-884

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scholarly article

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10.1111/ACEL.12496

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5

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15

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João Pedro de Magalhães

Michael Müller

Dudley W Lamming

Martin S Denzel

David M Sabatini

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2016-06-16T00:00:00Z

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27312235

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5013015

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