Therapeutic targeting of autophagy in disease: biology and pharmacology.
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Mechanisms of drug resistance in colon cancer and its therapeutic strategiesMitochondria-Associated Endoplasmic Reticulum Membranes Microenvironment: Targeting Autophagic and Apoptotic Pathways in Cancer TherapyDevelopment of autophagy inducers in clinical medicineMolecular switch role of Akt in Polygonatum odoratum lectin-induced apoptosis and autophagy in human non-small cell lung cancer A549 cellsInvestigating regulatory signatures of human autophagy related gene 5 (ATG5) through functional in silico analysisDiversity-Oriented Stapling Yields Intrinsically Cell-Penetrant Inducers of Autophagy.The effect of tetrandrine combined with cisplatin on proliferation and apoptosis of A549/DDP cells and A549 cells.Induction of autophagy contributes to crizotinib resistance in ALK-positive lung cancerThe importance of autophagy regulation in breast cancer development and treatment.MTOR inhibition enhances NVP-AUY922-induced autophagy-mediated KIT degradation and cytotoxicity in imatinib-resistant gastrointestinal stromal tumors.Autophagy: an emerging therapeutic target in vascular diseasesTetrandrine is a potent cell autophagy agonist via activated intracellular reactive oxygen speciesSmall-molecule enhancers of autophagy modulate cellular disease phenotypes suggested by human genetics.Lithium protects dopaminergic cells from rotenone toxicity via autophagy enhancement.A high-content screening platform with fluorescent chemical probes for the discovery of first-in-class therapeutics.Effect of beclin 1 expression on the biological behavior and chemotherapy sensitivity of cervical cancer cells.Novel autophagy inducers lentztrehaloses A, B and CDefective autophagy is a key feature of cerebral cavernous malformations.Autophagy regulation in the development and treatment of breast cancerACTP: A webserver for predicting potential targets and relevant pathways of autophagy-modulating compoundsPotential Therapeutic Benefits of Maintaining Mitochondrial Health in Peripheral Neuropathies.Autophagy and human diseases.Sirt3-mediated mitophagy protects tumor cells against apoptosis under hypoxia.Diosmetin inhibits cell proliferation and induces apoptosis by regulating autophagy via the mammalian target of rapamycin pathway in hepatocellular carcinoma HepG2 cells.The Proline/Arginine Dipeptide from Hexanucleotide Repeat Expanded C9ORF72 Inhibits the ProteasomeAutophagy regulates the survival of cells with chromosomal instability.Long non-coding RNAs act as regulators of cell autophagy in diseases (Review).Oncogenic and tumor suppressive roles of microRNAs in apoptosis and autophagy.Plant lectins, from ancient sugar-binding proteins to emerging anti-cancer drugs in apoptosis and autophagy.Recent advances in autophagy-based neuroprotection.Proteotoxicity and cardiac dysfunction.Temozolomide induces autophagy in primary and established glioblastoma cells in an EGFR independent manner.Adoptive Autophagy Activation: a Much-Needed Remedy Against Chemical Induced Neurotoxicity/Developmental Neurotoxicity.Autophagy and Obesity-Related Lung Disease.Targeting autophagy as a strategy for drug discovery and therapeutic modulation.Sorafenib and lithium chloride combination treatment shows promising synergistic effects in human glioblastoma multiforme cells in vitro but midkine is not implicated.Autophagy-from molecular mechanisms to clinical relevance.Relevance of autophagy to fatty liver diseases and potential therapeutic applications.Salidroside protects cortical neurons against glutamate-induced cytotoxicity by inhibiting autophagy.Ral GTPase and the exocyst regulate autophagy in a tissue-specific manner.
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Therapeutic targeting of autophagy in disease: biology and pharmacology.
description
article científic
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article scientifique
@fr
articolo scientifico
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artigo científico
@pt
bilimsel makale
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scientific article published on 13 August 2013
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Therapeutic targeting of autophagy in disease: biology and pharmacology.
@en
Therapeutic targeting of autophagy in disease: biology and pharmacology.
@nl
type
label
Therapeutic targeting of autophagy in disease: biology and pharmacology.
@en
Therapeutic targeting of autophagy in disease: biology and pharmacology.
@nl
prefLabel
Therapeutic targeting of autophagy in disease: biology and pharmacology.
@en
Therapeutic targeting of autophagy in disease: biology and pharmacology.
@nl
P2093
P2860
P356
P1476
Therapeutic targeting of autophagy in disease: biology and pharmacology.
@en
P2093
Jin-Ming Yang
William N Hait
Xingcong Ren
P2860
P304
P356
10.1124/PR.112.007120
P577
2013-08-13T00:00:00Z