The integrated landscape of driver genomic alterations in glioblastoma. - Wikidata - awgldk - TriplyDB

The integrated landscape of driver genomic alterations in glioblastoma.

The integrated landscape of driver genomic alterations in glioblastoma.

http://www.wikidata.org/entity/Q37237987

about

Identifying fusion transcripts using next generation sequencing Oncogenic kinase fusions: an evolving arena with innovative clinical opportunities The Role of Hedgehog Signaling in Tumor Induced Bone Disease NF-κB and STAT3 in glioblastoma: therapeutic targets coming of age Molecular characteristics of pediatric high-grade gliomas Navigating the rapids: the development of regulated next-generation sequencing-based clinical trial assays and companion diagnostics Cooperative integration between HEDGEHOG-GLI signalling and other oncogenic pathways: implications for cancer therapy Mouse models of cancer: Sleeping Beauty transposons for insertional mutagenesis screens and reverse genetic studies Contemporary murine models in preclinical astrocytoma drug development NTRK gene fusions as novel targets of cancer therapy across multiple tumour types Epidermal growth factor signaling in transformed cells TRKing down an old oncogene in a new era of targeted therapy An Oncogenic NTRK Fusion in a Patient with Soft-Tissue Sarcoma with Response to the Tropomyosin-Related Kinase Inhibitor LOXO-101 NTRK1 fusion in glioblastoma multiforme Recurrent chimeric fusion RNAs in non-cancer tissues and cells.Mitochondrial control by DRP1 in brain tumor initiating cells.Mutations in LZTR1 add to the complex heterogeneity of schwannomatosis Exploration of the gene fusion landscape of glioblastoma using transcriptome sequencing and copy number data Assessing CpG island methylator phenotype, 1p/19q codeletion, and MGMT promoter methylation from epigenome-wide data in the biomarker cohort of the NOA-04 trial.Fluorescence in situ hybridization in surgical pathology: principles and applications.Frequency of NFKBIA deletions is low in glioblastomas and skewed in glioblastoma neurospheres.The genetic landscape of anaplastic astrocytoma.The genomic landscape of diffuse intrinsic pontine glioma and pediatric non-brainstem high-grade glioma A novel approach to the discovery of survival biomarkers in glioblastoma using a joint analysis of DNA methylation and gene expression.FBXW7 mutations in melanoma and a new therapeutic paradigm Role of receptor tyrosine kinases and their ligands in glioblastoma.Somatic chromosomal engineering identifies BCAN-NTRK1 as a potent glioma driver and therapeutic target.EphA2 promotes infiltrative invasion of glioma stem cells in vivo through cross-talk with Akt and regulates stem cell properties.Quantitative proteomic analysis reveals effects of epidermal growth factor receptor (EGFR) on invasion-promoting proteins secreted by glioblastoma cells.Identification of causal genetic drivers of human disease through systems-level analysis of regulatory networks.Recurrent LRP1-SNRNP25 and KCNMB4-CCND3 fusion genes promote tumor cell motility in human osteosarcoma.Germline loss-of-function mutations in LZTR1 predispose to an inherited disorder of multiple schwannomas The hidden genetics of epilepsy-a clinically important new paradigm.Nuclear receptor corepressor complexes in cancer: mechanism, function and regulation Deregulated proliferation and differentiation in brain tumors.Neurotrophin signaling via TrkB and TrkC receptors promotes the growth of brain tumor-initiating cells.Sparse expression bases in cancer reveal tumor drivers.Complete clinical regression of a BRAF V600E-mutant pediatric glioblastoma multiforme after BRAF inhibitor therapy.Micro-environment causes reversible changes in DNA methylation and mRNA expression profiles in patient-derived glioma stem cells A unique four-hub protein cluster associates to glioblastoma progression.

P2860

Q26739900-66628670-A1B8-4A80-8138-B5B03ABDF319 Q26768158-BCB4BCF9-5552-42A0-B85D-40BFC03FBA98 Q26783615-EC97FF6B-E990-4CD4-AFA4-BC8DC9E1C2D1 Q26830388-0FD8A831-008E-4A02-8CB1-8CF349209148 Q26860786-B8290A4B-341F-424A-83F0-8DC55F79B0A4 Q26864332-36D1B6B8-FE4F-42C4-8ADE-839BBE0351CD Q26865136-F5D46B56-9409-456E-8E32-0304FA33B3DE Q27008537-EFA750BE-885A-425D-B2BD-A4A88DE567A0 Q27026937-261ED3F2-5641-40C2-B6E7-F825FFE90C3B Q28066821-44C7C781-2EF3-4969-A2D0-AFB7F3B23333 Q28084034-B1763159-ACE7-4A26-9252-02E0F0E32F3F Q28254287-A6B330BC-75DA-4AEF-B0CE-53EDCE6B3A47 Q28265615-5EB9E51E-6728-429F-9EEE-C1E71E006915 Q28541127-EDDBE9F7-5503-4A61-8EFC-D0A26A292439 Q30277623-2216729A-3C30-4BE3-8499-C9AEBA8D6BA6 Q30300490-44CA4A82-C612-4C00-A546-54347E12333F Q30394068-BDA1BE8B-2667-4DAE-92B7-14D18E190FC1 Q30699293-3F32565D-1757-4B1C-9B54-DD8F2B774832 Q30836702-70F15069-9A08-401B-ADFE-9890B9B54D83 Q33593910-4B2CC7E3-8179-470E-A9DE-913EAE7B1D85 Q33643498-46950EA6-9CAB-4FFF-9E66-67E53C56EC6E Q33688888-F055C5B3-A9A2-4857-BF60-189C7B31F5BA Q33751426-220AE2B7-9C10-41F6-8F63-34A10F78006E Q33784612-CC2D2506-47DE-4CF3-818E-CD376E5D2E38 Q33845217-7CC7C106-BC7A-4DCA-91B0-0B4DFDA0209C Q33883849-EB64E071-1619-4301-B32A-E262597FBF77 Q33899971-F039C301-3F8C-4DAD-AA47-803DC5BA1919 Q33993779-2B5D0075-783E-467B-8FEE-2D4B5484250A Q34303359-C0CB5527-787F-4988-8F4F-A61AB5B34C87 Q34324288-7AC66A50-E017-44FE-BD1E-F4021860366A Q34340295-18A0A8E3-AAD1-4F16-A406-DB29E2ED5BBE Q34393793-2015F8F0-58FB-4201-93C3-5E1331344C27 Q34415194-E0FD2D80-3260-4367-A873-572C87C174EC Q34448240-B1283FB1-1106-4202-96FB-216A1804C5FA Q34859989-6211A711-0837-47DC-8D29-5B6A8631229F Q35055652-2309C7F8-FC71-47F5-B7DF-FD851EC6CCD7 Q35088941-405F5151-ABA5-483B-B628-EE94471D72DA Q35146078-082017B9-460A-46BC-BBD8-83E9E702C5EC Q35146816-46F7AEF9-00CC-4011-8C3C-DEE9DD5DD565 Q35210961-FFD1BE5E-F973-41E9-92BD-9C6A9D2F55EF

P2860

The integrated landscape of driver genomic alterations in glioblastoma.

http://www.wikidata.org/entity/Q37237987

description

article científic

@ca

article scientifique

@fr

articolo scientifico

@it

artigo científico

@pt

bilimsel makale

@tr

scientific article published on 05 August 2013

@en

vedecký článok

@sk

vetenskaplig artikel

@sv

videnskabelig artikel

@da

vědecký článek

@cs

name

The integrated landscape of driver genomic alterations in glioblastoma.

@en

The integrated landscape of driver genomic alterations in glioblastoma.

@nl

type

label

The integrated landscape of driver genomic alterations in glioblastoma.

@en

The integrated landscape of driver genomic alterations in glioblastoma.

@nl

prefLabel

The integrated landscape of driver genomic alterations in glioblastoma.

@en

The integrated landscape of driver genomic alterations in glioblastoma.

@nl

P1433

Q37237987-5C405FCC-B015-4BAA-A298-098CFA70CC9A

P1476

Q37237987-BB30C075-C833-4E82-8140-4BB882AA1822

P2093

Q37237987-1CB2920F-DD19-4254-B559-E3605C948F8E

Q37237987-262AD7F7-7EA2-4F05-A36A-8D2D8366C170

Q37237987-321002B8-454D-44D5-BDFA-3E22A582CDBB

Q37237987-48343579-88E2-436B-B856-39CDBBCFFFFF

Q37237987-4D86FBF6-C5C7-426D-B018-00D5D24239BB

Q37237987-6851FC4B-9511-4682-B0FA-FF812FE263DD

Q37237987-6D1C315B-0CB6-4689-A70B-EAEDE8EA81D1

Q37237987-6E1655E9-7144-4AE2-B1DD-2CC8945B8EB2

Q37237987-7DB2421D-9DAF-4184-902D-46E7611231F5

Q37237987-83944CB9-4FC1-4645-9F3A-84517A69C9F4

P2860

Q37237987-00B8B85E-9027-411C-ADD9-F2103FD4BA65

Q37237987-040CA921-3066-48DE-A72F-679093099E0D

Q37237987-09DBBEED-AAE5-44B0-8215-AE173E69E006

Q37237987-0A78D8FB-210D-46AE-9144-92F667115694

Q37237987-165301D4-1D8B-4448-B545-AE4FBE56FDE3

Q37237987-1BF8FFA7-3BF9-4930-832F-D728D03860DC

Q37237987-1D5479CC-D71B-4D5A-A8E9-7D0CCA9586C2

Q37237987-23A65E67-72A9-4279-9E5A-F0D58780D205

Q37237987-267A495F-7945-4850-A7A1-B4FD54E93C66

Q37237987-28DB23B5-245F-4172-A9D8-E1CB510BB161

P2888

Q37237987-A1EB89D3-5A53-4615-8517-83A67F4A385B

P304

Q37237987-207461B5-6A00-40DB-AAE9-E4437B31CCC1

P31

Q37237987-FD7D88C7-0E99-4478-AF0F-433879CFFEEE

P356

Q37237987-628E822D-82E5-465C-BECB-74AD580A450A

P407

Q37237987-53D09114-34C6-4A29-B9FF-E10EBC41608C

P433

Q37237987-20995FE3-0E06-4BDE-B197-A0370BC6B4A4

P478

Q37237987-6013595A-0987-4472-B68B-F7C2D099B9D3

P50

Q37237987-3BC1A17A-D007-4AFA-BB01-620392B3D018

Q37237987-4265E0AB-ED65-448D-8A2C-EAEB5506CDFC

Q37237987-AB85CA2C-CE46-4A40-BEA8-DC4497FAA954

Q37237987-D6BBDB34-BFA1-4BAA-A266-2E6418F48E28

Q37237987-E096227D-A9A2-4CFE-A8B9-F66F0EB8A649

Q37237987-F75CE79F-D38F-43CC-876C-B5ACA4683A3C

Q37237987-F9B3C6DE-2A4D-45B3-BA55-37E8F500B616

P577

Q37237987-E7D14EE5-764D-40CE-8393-47310A09E922

P5875

Q37237987-7487E24C-4D7A-4248-B129-A2B14D636A09

P698

Q37237987-C8EF95C6-5DA5-4B01-995E-DD792392819B

P932

Q37237987-BBA9CD7A-0A4B-4FC4-B2C9-D56F97FBAB95

P356

P1433

Nature Genetics

P1476

The integrated landscape of driver genomic alterations in glioblastoma.

@en

P2093

Adriana Heguy

http://www.w3.org/2001/XMLSchema#string

Alan X Ji

http://www.w3.org/2001/XMLSchema#string

Angelica Castano

http://www.w3.org/2001/XMLSchema#string

Anna Lasorella

http://www.w3.org/2001/XMLSchema#string

Antonio Iavarone

http://www.w3.org/2001/XMLSchema#string

Carla Danussi

http://www.w3.org/2001/XMLSchema#string

David J Pisapia

http://www.w3.org/2001/XMLSchema#string

Francesco Abate

http://www.w3.org/2001/XMLSchema#string

Francesco Niola

http://www.w3.org/2001/XMLSchema#string

Gaetano Finocchiaro

http://www.w3.org/2001/XMLSchema#string

P2860

HERC2 coordinates ubiquitin-dependent assembly of DNA repair factors on damaged chromosomes

Structure of the Keap1:Nrf2 interface provides mechanistic insight into Nrf2 signaling

Ubiquitination of Keap1, a BTB-Kelch substrate adaptor protein for Cul3, targets Keap1 for degradation by a proteasome-independent pathway

KLHL3 mutations cause familial hyperkalemic hypertension by impairing ion transport in the distal nephron

BCOR regulates mesenchymal stem cell function by epigenetic mechanisms

Adaptor protein self-assembly drives the control of a cullin-RING ubiquitin ligase

Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles.

The genetic basis of early T-cell precursor acute lymphoblastic leukaemia.

I-TASSER: a unified platform for automated protein structure and function prediction

BRAF mutations in hairy-cell leukemia

P2888

P304

1141-1149

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1038/NG.2734

http://www.w3.org/2001/XMLSchema#string

P407

P433

10

http://www.w3.org/2001/XMLSchema#string

P478

45

http://www.w3.org/2001/XMLSchema#string

P50

Serena Pellegatta

Gilbert G Privé

Darell D. Bigner

Roger E McLendon

P577

2013-08-05T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

255688982

http://www.w3.org/2001/XMLSchema#string

P698

23917401

http://www.w3.org/2001/XMLSchema#string

P932

3799953

http://www.w3.org/2001/XMLSchema#string