A model of peptide triazole entry inhibitor binding to HIV-1 gp120 and the mechanism of bridging sheet disruption
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Covalent conjugation of a peptide triazole to HIV-1 gp120 enables intramolecular binding site occupancyMechanism of multivalent nanoparticle encounter with HIV-1 for potency enhancement of peptide triazole virus inactivation.Peptide Triazole Inactivators of HIV-1 Utilize a Conserved Two-Cavity Binding Site at the Junction of the Inner and Outer Domains of Env gp120.Disulfide Sensitivity in the Env Protein Underlies Lytic Inactivation of HIV-1 by Peptide Triazole Thiols.Peptide triazole inactivators of HIV-1: how do they work and what is their potential?Chemical optimization of macrocyclic HIV-1 inactivators for improving potency and increasing the structural diversity at the triazole ring.Recognition of HIV-inactivating peptide triazoles by the recombinant soluble Env trimer, BG505 SOSIP.664.Interactions of peptide triazole thiols with Env gp120 induce irreversible breakdown and inactivation of HIV-1 virions.
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A model of peptide triazole entry inhibitor binding to HIV-1 gp120 and the mechanism of bridging sheet disruption
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article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 22 March 2013
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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A model of peptide triazole en ...... m of bridging sheet disruption
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A model of peptide triazole en ...... of bridging sheet disruption.
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A model of peptide triazole en ...... m of bridging sheet disruption
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A model of peptide triazole en ...... of bridging sheet disruption.
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A model of peptide triazole en ...... m of bridging sheet disruption
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A model of peptide triazole en ...... of bridging sheet disruption.
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A model of peptide triazole en ...... m of bridging sheet disruption
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P2093
Ali Emileh
Cameron F Abrams
Carole A Bewley
Diogo R M Moreira
Ferit Tuzer
Herman Yeh
Irwin M Chaiken
Judith M Lalonde
Muddegowda Umashankara
P2860
P304
P356
10.1021/BI400166B
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P577
2013-03-22T00:00:00Z