Novel oncogenic PDGFRA mutations in pediatric high-grade gliomas. - Wikidata - awgldk - TriplyDB

Novel oncogenic PDGFRA mutations in pediatric high-grade gliomas.

Novel oncogenic PDGFRA mutations in pediatric high-grade gliomas.

http://www.wikidata.org/entity/Q37238690

about

Molecular Biology in Pediatric High-Grade Glioma: Impact on Prognosis and Treatment Pathology, Molecular Genetics, and Epigenetics of Diffuse Intrinsic Pontine Glioma Molecular characteristics of pediatric high-grade gliomas Spatial genomic heterogeneity in diffuse intrinsic pontine and midline high-grade glioma: implications for diagnostic biopsy and targeted therapeutics Regorafenib: Antitumor Activity upon Mono and Combination Therapy in Preclinical Pediatric Malignancy Models The therapeutic potential of targeting the PI3K pathway in pediatric brain tumors A high-throughput in vitro drug screen in a genetically engineered mouse model of diffuse intrinsic pontine glioma identifies BMS-754807 as a promising therapeutic agent Diffuse Intrinsic Pontine Glioma: New Pathophysiological Insights and Emerging Therapeutic Targets Cell of origin for malignant gliomas and its implication in therapeutic development A phase I study of perifosine with temsirolimus for recurrent pediatric solid tumors.Pediatric high-grade glioma: biologically and clinically in need of new thinking Targeting the PDGF signaling pathway in tumor treatment Pax3 expression enhances PDGF-B-induced brainstem gliomagenesis and characterizes a subset of brainstem glioma.Increased 5-hydroxymethylcytosine and decreased 5-methylcytosine are indicators of global epigenetic dysregulation in diffuse intrinsic pontine glioma Array-based comparative genomic hybridization analysis reveals chromosomal copy number aberrations associated with clinical outcome in canine diffuse large B-cell lymphoma.Identification of a novel MET mutation in high-grade glioma resulting in an auto-active intracellular protein Single-cell sequencing maps gene expression to mutational phylogenies in PDGF- and EGF-driven gliomas Repurposing the anti-epileptic drug sodium valproate as an adjuvant treatment for diffuse intrinsic pontine glioma.A Novel Mouse Model of Diffuse Intrinsic Pontine Glioma Initiated in Pax3-Expressing Cells.Unique genetic and epigenetic mechanisms driving paediatric diffuse high-grade glioma.Pediatric gliomas as neurodevelopmental disorders Genetic alterations in uncommon low-grade neuroepithelial tumors: BRAF, FGFR1, and MYB mutations occur at high frequency and align with morphology.Pediatric Brain Tumors: Current Knowledge and Therapeutic Opportunities Glioma: experimental models and reality.The prognostic role of intragenic copy number breakpoints and identification of novel fusion genes in paediatric high grade glioma.Nanotechnology Applications for Diffuse Intrinsic Pontine Glioma.Genomic Insights into Diffuse Intrinsic Pontine Glioma.Paediatric and adult glioblastoma: multiform (epi)genomic culprits emerge.The genetic signatures of pediatric high-grade glioma: no longer a one-act play.Molecular insights into pediatric brain tumors have the potential to transform therapy.Management of diffuse intrinsic pontine glioma in children: current and future strategies for improving prognosis.Target and Agent Prioritization for the Children's Oncology Group-National Cancer Institute Pediatric MATCH Trial.Histone Variant H3.3: A versatile H3 variant in health and in disease.Histone H3.3K27M Represses p16 to Accelerate Gliomagenesis in a Murine Model of DIPG.Targeting the VEGF and PDGF signaling pathway in glioblastoma treatment.Recent Advances on the Molecular Pathology of Glial Neoplasms in Children and Adults.Preclinical evaluation of dasatinib alone and in combination with cabozantinib for the treatment of diffuse intrinsic pontine glioma.Molecular pathology of paediatric central nervous system tumours.Characterization of gliomas: from morphology to molecules.Biopsy in a series of 130 pediatric diffuse intrinsic Pontine gliomas.

P2860

Q26785952-736B2866-1799-4E0E-9B7C-D657C3B29B76 Q26801528-C555FB39-12D2-4A5B-8132-68CBAEC884E7 Q26860786-42FD2CEC-7E64-46FB-A102-2A262A21FCD6 Q27317083-3FE6AFE4-81E1-4244-A045-E7E5503CAE81 Q27345024-D7A4634C-CB5B-4DD2-A194-DBCF60ABBDB7 Q28070264-DB77022A-4A71-4E8A-92D2-796BDB8F75E5 Q28543923-7D97BF2A-D453-4DEE-B7E9-687135306F44 Q30251385-C5DEC91E-EC18-402C-B024-D313492C43A7 Q30300877-FB105F72-AE88-4F4A-8EFF-9AFB7214486B Q33438006-81607415-8545-4759-816B-223181710273 Q33777868-F5418C69-A57F-4C9E-A524-380E616BD0E2 Q34393461-747AB75D-D1C1-4849-BD22-666985C2E4E7 Q34410560-456B9684-EDBF-4DA9-94D3-4F01EC8A7842 Q34500349-22C6E02C-448F-4D5D-BC94-53A867E7E7C6 Q35396525-03A1A738-B296-4A21-840A-AAF7923DE4A8 Q35747784-16A4E9C0-D84F-4EDA-A10D-4BCB4986EFE5 Q36204396-010C124A-9D9A-4285-9AA5-B0E02B11481D Q36380213-53347339-06B6-4C98-9445-5A6C54719088 Q36527913-A488D19B-23E8-4ED1-B6F9-B885DAC0B8BB Q36561184-FA0A3A14-1864-438C-B71E-A9754D9649B0 Q36803476-23FCEC73-A94D-4981-AB1E-F84C1A331CE0 Q36900873-D90B7293-5424-4DC3-B3E0-185367DAC143 Q37213305-7A153A0D-F63E-4EC9-AA22-0ABC12E5FF04 Q37596796-C8F55679-CFB8-4D31-98EB-ABAAB6B7A06E Q37609740-C69D50B6-C7C3-4765-A6C6-5C09707AC235 Q37668050-9FFB332D-DF23-4804-AAA3-3D92C45F53D0 Q37723508-BFDA9673-BC24-4BFA-B999-79C9645509BE Q37729676-52D4B006-A320-4C68-BD3F-FFD69C9E0ECB Q38248990-2B5E6F34-2165-435E-BACF-3B6EA72C11F7 Q38268366-8DC8A5B9-7E97-47A5-900B-E504D10ED39C Q38273428-86A7EFE2-2328-4C96-BEFB-AD3B73D44488 Q38371672-80A63CB0-9F81-4C5D-9ABD-D56AC5896411 Q38716435-8C5289E7-50B9-4363-9319-F7A9C33DA5A6 Q38776008-C14A3C83-1187-4A55-9A15-74FD8F6E6F62 Q38838030-072DC922-247E-4741-9B7C-9C1D794FD394 Q38905187-B78E22EB-BC6A-476A-ACE7-49A95F6F5F74 Q38926034-FF37F19C-E2F3-4502-A891-155D2E90C00E Q38971961-7908FBD3-25E8-4909-AD3C-3C56319FF199 Q39412967-B97D8B25-9D75-4B43-9B66-0C7E87E5B572 Q40560681-3D03B968-83AA-468A-A620-DA30009FD943

P2860

Novel oncogenic PDGFRA mutations in pediatric high-grade gliomas.

http://www.wikidata.org/entity/Q37238690

description

article científic

@ca

article scientifique

@fr

articolo scientifico

@it

artigo científico

@pt

bilimsel makale

@tr

scientific article published on 22 August 2013

@en

vedecký článok

@sk

vetenskaplig artikel

@sv

videnskabelig artikel

@da

vědecký článek

@cs

name

Novel oncogenic PDGFRA mutations in pediatric high-grade gliomas.

@en

Novel oncogenic PDGFRA mutations in pediatric high-grade gliomas.

@nl

type

label

Novel oncogenic PDGFRA mutations in pediatric high-grade gliomas.

@en

Novel oncogenic PDGFRA mutations in pediatric high-grade gliomas.

@nl

prefLabel

Novel oncogenic PDGFRA mutations in pediatric high-grade gliomas.

@en

Novel oncogenic PDGFRA mutations in pediatric high-grade gliomas.

@nl

P1433

Q37238690-E822944A-878F-42CF-81FC-C7F09FB71999

P1476

Q37238690-C076A949-E92B-489C-9137-88FD6B12E2C9

P2093

Q37238690-05350944-6066-4613-BE2B-AFDD4A8EA82B

Q37238690-5BE807E9-07E7-4C44-960D-DD44FFA5B78C

Q37238690-85FF2C92-7C7E-450A-9A29-8C4AE16F48C0

Q37238690-88CF2C83-324A-46F3-802B-3292A757220E

Q37238690-94CE3A18-2A52-4460-A6DF-8AFC5DA984C6

Q37238690-9CD3A935-F115-4204-BDAC-AA29F9987570

Q37238690-B0B83BC3-9BE4-4FCD-81C0-D0894B4560BA

Q37238690-BDF8A5C2-FC81-4D4B-89DD-C20AB6DAF92F

Q37238690-C6E58881-F780-47FA-8B76-F54FA3C772A7

Q37238690-D004C444-F70E-4E9D-B777-9EC98309C0CC

P2860

Q37238690-00AF94D1-4CAD-45A2-BF58-EEDC13D1EC3A

Q37238690-082AB46D-6FD5-49BD-B41C-30128F04B62C

Q37238690-0C1E230D-38A5-4C53-B6C2-4A37C77A3E76

Q37238690-0C37889F-C029-46C8-8AF1-6D26E9FF2FA0

Q37238690-141E9E4B-3C13-46F1-A6FA-7AFA5960A953

Q37238690-154F7EDF-1C30-4B6A-847F-269D80BE5ED5

Q37238690-1CDF6A97-8DCE-48B3-B6BB-F4E0485E47E3

Q37238690-26D55EA4-2194-4F0F-AF29-671C36B5DC4C

Q37238690-27004229-F83A-4413-8DAF-99141F125DB1

Q37238690-27B0D0EC-36B8-4CAA-9319-F480DC5F0C15

P304

Q37238690-361D6830-B5E7-4085-A718-5A6D30749215

P31

Q37238690-25A726C5-22AD-46AB-BF11-A58B66F74C59

P356

Q37238690-ED8217A5-36AA-423A-A2AE-E0358362345A

P407

Q37238690-95108204-E7DC-4D03-B913-924771D8A766

P433

Q37238690-3C6783AF-E138-4021-A04A-EFBC1D1CA442

P478

Q37238690-A83AFC69-8FAA-49AD-9912-7893506F13C1

P50

Q37238690-1F376C84-25AC-49E9-AC21-C865BB03E914

Q37238690-76C5AEE8-0925-4186-B9B4-B9ABAF465D89

Q37238690-C84E9B37-75A1-4B24-8721-2312E5A15720

Q37238690-E602B8E7-AF1B-4EB6-8DC7-72EC7E5E1F8F

P577

Q37238690-E8BD730B-6857-444A-BA19-6EC99C2FFB37

P698

Q37238690-76010038-BFE2-4E48-86F5-ECA4F7070411

P932

Q37238690-A086EDC5-14FE-46AF-BE06-B002D8703AFA

P356

0008-5472.CAN-13-1491

P1433

Cancer Research

P1476

Novel oncogenic PDGFRA mutations in pediatric high-grade gliomas.

@en

P2093

Alexander K Diaz

http://www.w3.org/2001/XMLSchema#string

Arzu Onar-Thomas

http://www.w3.org/2001/XMLSchema#string

Barbara S Paugh

http://www.w3.org/2001/XMLSchema#string

Chunxu Qu

http://www.w3.org/2001/XMLSchema#string

Cynthia Wetmore

http://www.w3.org/2001/XMLSchema#string

David W Ellison

http://www.w3.org/2001/XMLSchema#string

Diana Carvalho

http://www.w3.org/2001/XMLSchema#string

Dorine A Bax

http://www.w3.org/2001/XMLSchema#string

Jinghui Zhang

http://www.w3.org/2001/XMLSchema#string

Junyuan Zhang

http://www.w3.org/2001/XMLSchema#string

P2860

Tyrosine mutations within the alpha platelet-derived growth factor receptor kinase insert domain abrogate receptor-associated phosphatidylinositol-3 kinase activity without affecting mitogenic or chemotactic signal transduction

Somatic histone H3 alterations in pediatric diffuse intrinsic pontine gliomas and non-brainstem glioblastomas

Phase I study of the safety, tolerability, and pharmacokinetics of oral CP-868,596, a highly specific platelet-derived growth factor receptor tyrosine kinase inhibitor in patients with advanced cancers

An integrated genomic analysis of human glioblastoma multiforme

Integrated genomic analysis identifies clinically relevant subtypes of glioblastoma characterized by abnormalities in PDGFRA, IDH1, EGFR, and NF1

Comprehensive genomic characterization defines human glioblastoma genes and core pathways

The 2007 WHO classification of tumours of the central nervous system

PDGFRA mutations in gastrointestinal stromal tumors: frequency, spectrum and in vitro sensitivity to imatinib.

Crenolanib inhibits the drug-resistant PDGFRA D842V mutation associated with imatinib-resistant gastrointestinal stromal tumors.

Gain-of-function mutations of c-kit in human gastrointestinal stromal tumors

P304

6219-6229

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1158/0008-5472.CAN-13-1491

http://www.w3.org/2001/XMLSchema#string

P407

P433

20

http://www.w3.org/2001/XMLSchema#string

P478

73

http://www.w3.org/2001/XMLSchema#string

P50

Alberto Broniscer

Rui Manuel Reis

Raelene Endersby

P577

2013-08-22T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P698

23970477

http://www.w3.org/2001/XMLSchema#string

P932

3800209

http://www.w3.org/2001/XMLSchema#string