Controversial issue: is it safe to employ mesenchymal stem cells in cell-based therapies?
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Sox11 is expressed in early progenitor human multipotent stromal cells and decreases with extensive expansion of the cellsOptimization of pre-transplantation conditions to enhance the efficacy of mesenchymal stem cellsSpheroid Culture of Mesenchymal Stem CellsIsolation of a stable subpopulation of mobilized dental pulp stem cells (MDPSCs) with high proliferation, migration, and regeneration potential is independent of age.Conditioned media from mesenchymal stromal cells restore sodium transport and preserve epithelial permeability in an in vitro model of acute alveolar injury.Hybrid composites of mesenchymal stem cell sheets, hydroxyapatite, and platelet-rich fibrin granules for bone regeneration in a rabbit calvarial critical-size defect model.How to track cellular aging of mesenchymal stromal cells?Airway delivery of soluble factors from plastic-adherent bone marrow cells prevents murine asthma.Concise review: mind the gap: challenges in characterizing and quantifying cell- and tissue-based therapies for clinical translation.Stem cells as therapeutic vehicles for the treatment of high-grade gliomas.Stem cells and regenerative medicine: accomplishments to date and future promise.Uncultured marrow mononuclear cells delivered within fibrin glue hydrogels to porous scaffolds enhance bone regeneration within critical-sized rat cranial defects.Deterministic and stochastic approaches in the clinical application of mesenchymal stromal cells (MSCs).Translating research into clinical scale manufacturing of mesenchymal stromal cells.Risk factors in the development of stem cell therapyIn vivo biofunctional evaluation of hydrogels for disc regeneration.Human adipose stromal cells (ASC) for the regeneration of injured cartilage display genetic stability after in vitro culture expansion.Proof of principle: quality control of therapeutic cell preparations using senescence-associated DNA-methylation changes.Chondrogenesis by chemotactic homing of synovium, bone marrow, and adipose stem cells in vitro.Stem cell conditioned culture media attenuated albumin-induced epithelial-mesenchymal transition in renal tubular cells.Replicative senescence of mesenchymal stem cells causes DNA-methylation changes which correlate with repressive histone marksMesenchymal stem cells for cardiac regeneration: translation to bedside realityAn Evaluation of the Stemness, Paracrine, and Tumorigenic Characteristics of Highly Expanded, Minimally Passaged Adipose-Derived Stem CellsIntercellular cytosolic transfer correlates with mesenchymal stromal cell rescue of umbilical cord blood cell viability during ex vivo expansionToward personalized cell therapies by using stem cells: seven relevant topics for safety and success in stem cell therapy.Stem cell conditioned medium improves acute lung injury in mice: in vivo evidence for stem cell paracrine action.c-Maf regulates pluripotency genes, proliferation/self-renewal, and lineage commitment in ROS-mediated senescence of human mesenchymal stem cells.Upregulation of Adipogenesis and Chondrogenesis in MSC Serum-Free Culture.Pleiotropic effects of cancer cells' secreted factors on human stromal (mesenchymal) stem cells.Inflammation and mesenchymal stem cell agingHuman stromal (mesenchymal) stem cells: basic biology and current clinical use for tissue regeneration.Precision manufacturing for clinical-quality regenerative medicines.Tissue engineering for the oncologic urinary bladder.Insights into bone marrow-derived mesenchymal stem cells safety for cutaneous repair and regeneration.Mesenchymal stem cells for the treatment and prevention of graft-versus-host disease: experiments and practice.Concise review: bridging the gap: bone regeneration using skeletal stem cell-based strategies - where are we now?Platelet lysate as replacement for fetal bovine serum in mesenchymal stromal cell cultures.The challenge of pancreatic cancer therapy and novel treatment strategy using engineered mesenchymal stem cells.An update of human mesenchymal stem cell biology and their clinical uses.The regulatory sciences for stem cell-based medicinal products.
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P2860
Controversial issue: is it safe to employ mesenchymal stem cells in cell-based therapies?
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
@pt
bilimsel makale
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scientific article published on 24 July 2008
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Controversial issue: is it safe to employ mesenchymal stem cells in cell-based therapies?
@en
Controversial issue: is it safe to employ mesenchymal stem cells in cell-based therapies?
@nl
type
label
Controversial issue: is it safe to employ mesenchymal stem cells in cell-based therapies?
@en
Controversial issue: is it safe to employ mesenchymal stem cells in cell-based therapies?
@nl
prefLabel
Controversial issue: is it safe to employ mesenchymal stem cells in cell-based therapies?
@en
Controversial issue: is it safe to employ mesenchymal stem cells in cell-based therapies?
@nl
P2093
P1476
Controversial issue: is it safe to employ mesenchymal stem cells in cell-based therapies?
@en
P2093
Angelika Jamnig
Gerhard Laschober
Günter Lepperdinger
P304
P356
10.1016/J.EXGER.2008.07.004
P577
2008-07-24T00:00:00Z