Instability of assembled T-cell receptor complex that is associated with rapid degradation of zeta chains in immature CD4+CD8+ thymocytes.
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Tonic ubiquitylation controls T-cell receptor:CD3 complex expression during T-cell developmentTranscriptional regulation of the T cell antigen receptor zeta subunit: identification of a tissue-restricted promoterEarly molecular events induced by T cell receptor (TCR) signaling in immature CD4+ CD8+ thymocytes: increased synthesis of TCR-alpha protein is an early response to TCR signaling that compensates for TCR-alpha instability, improves TCR assembly, andDevelopmental regulation of alpha beta T cell antigen receptor expression results from differential stability of nascent TCR alpha proteins within the endoplasmic reticulum of immature and mature T cells.A selective defect in IgM antigen receptor synthesis and transport causes loss of cell surface IgM expression on tolerant B lymphocytes.Developmental and functional impairment of T cells in mice lacking CD3 zeta chains.Coexistent T-cell lymphoblastic lymphoma and an atypical myeloproliferative disorder associated with t(8;13)(p21;q14).Do structural changes of T cell receptor complex occur in tumor-bearing state?
P2860
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P2860
Instability of assembled T-cell receptor complex that is associated with rapid degradation of zeta chains in immature CD4+CD8+ thymocytes.
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article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on October 1992
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Instability of assembled T-cel ...... immature CD4+CD8+ thymocytes.
@en
Instability of assembled T-cel ...... immature CD4+CD8+ thymocytes.
@nl
type
label
Instability of assembled T-cel ...... immature CD4+CD8+ thymocytes.
@en
Instability of assembled T-cel ...... immature CD4+CD8+ thymocytes.
@nl
prefLabel
Instability of assembled T-cel ...... immature CD4+CD8+ thymocytes.
@en
Instability of assembled T-cel ...... immature CD4+CD8+ thymocytes.
@nl
P2093
P2860
P356
P1476
Instability of assembled T-cel ...... immature CD4+CD8+ thymocytes.
@en
P2093
P2860
P304
P356
10.1073/PNAS.89.20.9494
P407
P577
1992-10-01T00:00:00Z