Transcription-independent functions of MYC: regulation of translation and DNA replication
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MicroRNA-34a modulates c-Myc transcriptional complexes to suppress malignancy in human prostate cancer cellsProteomic profiling of Myc-associated proteinsThe histone deacetylase SIRT2 stabilizes Myc oncoproteinsRegulation of mRNA cap methylationMYC on the path to cancerGlobal MYCN transcription factor binding analysis in neuroblastoma reveals association with distinct E-box motifs and regions of DNA hypermethylation.Functional and gene network analyses of transcriptional signatures characterizing pre-weaned bovine mammary parenchyma or fat pad uncovered novel inter-tissue signaling networks during developmentThe Dual Roles of MYC in Genomic Instability and Cancer ChemoresistanceMyc proteins as therapeutic targets.Promotion of direct reprogramming by transformation-deficient Myc.MYC cofactors: molecular switches controlling diverse biological outcomes.Transcriptional amplification in tumor cells with elevated c-Myc.Epigenetic heredity of human height.Drosophila Myc interacts with host cell factor (dHCF) to activate transcription and control growthTranscriptional Regulation of CRD-BP by c-myc: Implications for c-myc FunctionsThe opposing transcriptional functions of Sin3a and c-Myc are required to maintain tissue homeostasis.MicroRNA-34a suppresses malignant transformation by targeting c-Myc transcriptional complexes in human renal cell carcinoma.Structurally diverse c-Myc inhibitors share a common mechanism of action involving ATP depletion.The epigenetic control of E-box and Myc-dependent chromatin modifications regulate the licensing of lamin B2 origin during cell cycle.Myc coordinates transcription and translation to enhance transformation and suppress invasiveness.c-Myc suppression of DNA double-strand break repair.Repurposing the anti-malarial drug artesunate as a novel therapeutic agent for metastatic renal cell carcinoma due to its attenuation of tumor growth, metastasis, and angiogenesis.MYCN and the epigenomeDirect reprogramming by oncogenic Ras and Myc.Back to the origin: reconsidering replication, transcription, epigenetics, and cell cycle control.Activated α2-Macroglobulin Regulates Transcriptional Activation of c-MYC Target Genes through Cell Surface GRP78 Protein.Characterization of MYC-induced tumorigenesis by in situ lipid profiling.Inactivation of CDK2 is synthetically lethal to MYCN over-expressing cancer cells.Cdc45 is a critical effector of myc-dependent DNA replication stress.MYC and transcription elongation.Key signalling nodes in mammary gland development and cancer: Myc.Translation initiation: a critical signalling node in cancer.Multiple Roles of MYC in Integrating Regulatory Networks of Pluripotent Stem Cells.Enigmatic MYC Conducts an Unfolding Systems Biology Symphony.Defining the molecular basis of tumor metabolism: a continuing challenge since Warburg's discovery.Translational control of cell fate: from integration of environmental signals to breaching anticancer defense.Oxidized low density lipoprotein, stem cells, and atherosclerosis.MYC oncogene in myeloid neoplasias.MYC-associated and double-hit lymphomas: a review of pathobiology, prognosis, and therapeutic approaches.Molecular definition of the pro-tumorigenic phenotype of glioma-activated microglia.
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Transcription-independent functions of MYC: regulation of translation and DNA replication
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
@pt
bilimsel makale
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scientific article published on 13 August 2008
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Transcription-independent functions of MYC: regulation of translation and DNA replication
@en
Transcription-independent func ...... anslation and DNA replication.
@nl
type
label
Transcription-independent functions of MYC: regulation of translation and DNA replication
@en
Transcription-independent func ...... anslation and DNA replication.
@nl
prefLabel
Transcription-independent functions of MYC: regulation of translation and DNA replication
@en
Transcription-independent func ...... anslation and DNA replication.
@nl
P2860
P356
P1476
Transcription-independent functions of MYC: regulation of translation and DNA replication
@en
P2093
Michael D Cole
P2860
P2888
P304
P356
10.1038/NRM2467
P577
2008-08-13T00:00:00Z