Simultaneous PET imaging of P-glycoprotein inhibition in multiple tissues in the pregnant nonhuman primate
about
Optimized approaches for quantification of drug transporters in tissues and cells by MRM proteomicsDisrupting P-glycoprotein function in clinical settings: what can we learn from the fundamental aspects of this transporter?Role of (drug) transporters in imaging in health and disease.Positron emission tomography imaging of tissue P-glycoprotein activity during pregnancy in the non-human primateXenobiotic, bile acid, and cholesterol transporters: function and regulation.Regional P-glycoprotein activity and inhibition at the human blood-brain barrier as imaged by positron emission tomography.ATP-binding cassette efflux transporters in human placenta.Molecular Imaging of Membrane Transporters' Activity in Cancer: a Picture is Worth a Thousand Tubes.Drug Interactions at the Human Placenta: What is the Evidence?Modulation of P-glycoprotein at the Human Blood-Brain Barrier by Quinidine or Rifampin Treatment: A Positron Emission Tomography Imaging Study.Modeling cyclosporine A inhibition of the distribution of a P-glycoprotein PET ligand, 11C-verapamil, into the maternal brain and fetal liver of the pregnant nonhuman primate: impact of tissue blood flow and site of inhibition.Bioluminescent imaging of ABCG2 efflux activity at the blood-placenta barrierPET and SPECT radiotracers to assess function and expression of ABC transporters in vivoDrug interactions at the blood-brain barrier: fact or fantasy?P-glycoprotein related drug interactions: clinical importance and a consideration of disease states.Functional characterization of drug uptake and metabolism in the heart.Using positron emission tomography to study transporter-mediated drug-drug interactions in tissues.Antiepileptic drugs alter the expression of placental carriers: An in vitro study in a human placental cell line.Imaging transporters: Transforming diagnostic and therapeutic development.Placental ABC Transporters: Biological Impact and Pharmaceutical Significance.TOTAL-BODY PET: MAXIMIZING SENSITIVITY TO CREATE NEW OPPORTUNITIES FOR CLINICAL RESEARCH AND PATIENT CARE.P-gp/ABCB1 exerts differential impacts on brain and fetal exposure to norbuprenorphine.Discrepancies in the P-glycoprotein-mediated transport of (18)F-MPPF: a pharmacokinetic study in mice and non-human primates.Mechanisms and the clinical relevance of complex drug-drug interactionsInterleukin-2 induces the in vitro maturation of human pluripotent stem cell-derived intestinal organoids
P2860
Q26851693-28575C7A-FA74-467B-AF60-F273A8C57F18Q28069761-B1C9A73D-7E9E-4B1F-8179-C3CFD7BBEE48Q30854787-81F1B2E0-1E82-4F9C-87F8-87197B367681Q33673118-FBEB52C9-C3F0-4EC4-BAB3-9BE959D7ECB7Q33714593-3408BABA-540A-40E9-AC1A-FF989112E3CFQ34125735-60F3E9EB-6843-4BF5-8BB9-B572FEC8776FQ34843023-FC40F09F-18CB-4C58-A2F3-259382AAD19FQ35768413-9B9DA6DB-9262-4060-925F-75467862DDA3Q36081992-CF17B45B-3DA7-46A6-8F4B-D412281C7688Q36186141-97CEB4D0-C0BB-44A8-970C-BC9487207CD5Q36525662-72459144-1DE5-4AFE-8C2E-1A3C3EC00AA5Q36555565-5277611E-B935-4740-9158-2D567C47CCECQ36953090-BD112606-1DFA-4B6A-A96F-5A994EC05CB7Q37362486-90B11045-1F1C-4EC1-8F2C-8AA6E81E9814Q37732337-3F0DCCD2-55EB-4575-B664-EAD0213C3D00Q37922773-EDBAB7DE-1C2C-44F6-81AF-09F23168D482Q38200490-866737B3-5D07-4CF0-8661-F06680F84041Q38868683-3482A61D-52DB-4659-AB0F-1E191C013E2EQ38871905-CBD63221-EEFB-4C97-8936-CEFB53ADE5C7Q38958745-4D5402C7-4BB7-4E3F-AB76-4767CB337D5BQ46035229-2AB8EE6B-A208-45DC-8C28-6AFE6B40390CQ47988249-4A469BE0-035F-46C9-9162-5A8E152FFFAAQ48490305-665DF571-102B-42E4-8607-662C258D85E3Q57490721-F066A1CE-E3D2-4161-A880-3B4AB5B3FE2CQ58803626-AA997DAC-9995-4835-A57E-D908FD8D574C
P2860
Simultaneous PET imaging of P-glycoprotein inhibition in multiple tissues in the pregnant nonhuman primate
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on May 2009
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Simultaneous PET imaging of P- ...... the pregnant nonhuman primate
@en
Simultaneous PET imaging of P- ...... the pregnant nonhuman primate.
@nl
type
label
Simultaneous PET imaging of P- ...... the pregnant nonhuman primate
@en
Simultaneous PET imaging of P- ...... the pregnant nonhuman primate.
@nl
prefLabel
Simultaneous PET imaging of P- ...... the pregnant nonhuman primate
@en
Simultaneous PET imaging of P- ...... the pregnant nonhuman primate.
@nl
P2093
P2860
P1476
Simultaneous PET imaging of P- ...... the pregnant nonhuman primate
@en
P2093
Amal Kaddoumi
David A Mankoff
Finbarr O'Sullivan
Francisco S Chung
Jashvant D Unadkat
Jeanne M Link
Mary F Hebert
P2860
P304
P356
10.2967/JNUMED.108.059360
P407
P50
P577
2009-05-01T00:00:00Z